Results 231 to 240 of about 198,084 (294)

The mitotic spindle kinase MSK co-ordinates segregation of the nucleus and kinetoplast in Leishmania mexicana

Carnielli JBT, Geoghegan V, Brannigan JA, Saldivia M, Hughes C, Lima APCA, Motta MCM, Dowle A, Wilkinson AJ, Mottram JC.   +9 more
europepmc   +1 more source

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

Advanced Science, Volume 13, Issue 50, 7 September 2026.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble, Wiktor Zywicki, Enrico Lucarelli, Ania Naila Guerrieri, Francesca Taraballi, Gianluca Cidonio, Claudia Di Bella, Carmine Onofrillo, Andrea J. O'Connor, Serena Duchi   +9 more
wiley   +1 more source

Kinesin-5/Cut7 C-terminal tail phosphorylation is essential for microtubule sliding force and bipolar mitotic spindle assembly. [PDF]

Curr Biol
Jones MH, Gergely ZR, Steckhahn D, Zhou B, Betterton MD.   +4 more
europepmc   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, Volume 13, Issue 51, 14 September 2026.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

Mechanisms underlying Myosin 10's contribution to the maintenance of mitotic spindle bipolarity. [PDF]

Mol Biol Cell
Yim YI, Pedrosa A, Wu X, Chinthalapudi K, Cheney RE, Hammer JA.   +5 more
europepmc   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu, Yalin Liu, Rongyi Wang, Wenwen Xu, Hao Shi, Ning Huang, Junlin Teng, Jin Meng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

CTCF is essential for proper mitotic spindle structure and anaphase segregation. [PDF]

Chromosoma
Chiu K, Berrada Y, Eskndir N, Song D, Fong C, Naughton S, Chen T, Moy S, Gyurmey S, James L, Ezeiruaku C, Capistran C, Lowey D, Diwanji V, Peterson S, Parakh H, Burgess AR, Probert C, Zhu A, Anderson B, Levi N, Gerlitz G, Packard MC, Dorfman KA, Bahiru MS, Stephens AD.   +25 more
europepmc   +1 more source

The Small but Versatile Cyclin‐Dependent Kinase Subunit CKS

BioEssays, Volume 48, Issue 9, September 2026.
The cyclin‐dependent kinase subunit, CKS, is required for anaphase onset during both meiosis I and II in Caenorhabditis elegans oocytes. One model for how CKS promotes meiosis II anaphase onset involves phosphorylation of a Cullin 2 E3 ligase by CDK/CKS/CYB‐3, followed by the CKS anion pocket binding to the phosphorylated E3, recruiting CDK/CKS/CYB‐1 ...
Jie Yang, Bruce Bowerman
wiley   +1 more source

Giant Primary Ovarian Leiomyoma Mimicking Ovarian Malignancy in an Elderly Postmenopausal Woman: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Ovarian leiomyomas, either primary or parasitic in origin, are exceptionally rare and account for about 0.5% to 1% of all benign ovarian tumors. They often pose a diagnostic challenge, particularly in postmenopausal women, as they can clinically and radiologically mimic ovarian malignancy.
John Lugata, Nasra Batchu, Onesmo Mrosso, Jaynes Kabuhaya, Esther Pinches, Glory Maringo, Eusebious Maro, Bariki Mchome, Alex Mremi   +8 more
wiley   +1 more source

A missense SNP in the tumor suppressor SETD2 reduces H3K36me3 and mitotic spindle integrity in Drosophila. [PDF]

Genetics
Brockett JS, Manalo T, Zein-Sabatto H, Lee J, Fang J, Chu P, Feng H, Patil D, Davidson P, Ogan K, Master VA, Pattaras JG, Roberts DL, Bergquist SH, Reyna MA, Petros JA, Lerit DA, Arnold RS.   +17 more
europepmc   +1 more source