Results 251 to 260 of about 198,084 (294)
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Nature, 1971
I PREVIOUSLY suggested that the shape of the metaphase spindle cannot be maintained if there is tension in the component microtubules1. Spindle tension has been detected2,3 and could be due to some other component pulling the chromosomes over the rigid microtubular framework.
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I PREVIOUSLY suggested that the shape of the metaphase spindle cannot be maintained if there is tension in the component microtubules1. Spindle tension has been detected2,3 and could be due to some other component pulling the chromosomes over the rigid microtubular framework.
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Mitotic Spindle Assembly In Vitro
Current Protocols in Cell Biology, 2001AbstractThe protocols in this unit describe the preparation of materials for an in vitro assay of mitotic spindle assembly in Xenopus egg extracts. Fluorochrome‐labeled tubulin is used to visualize microtubule asters and spindles.
J, Merlie, R, Heald
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Control of Mitotic Spindle Length
Annual Review of Cell and Developmental Biology, 2010The mitotic spindle accurately segregates genetic instructions by moving chromosomes to spindle poles (anaphase A) and separating the poles (anaphase B) so that, in general, the chromosomes and poles are positioned near the centers of the nascent daughter cell products of each cell division.
Gohta, Goshima, Jonathan M, Scholey
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1984
Publisher Summary This chapter focuses on one aspect of the biochemistry of mitotic spindles—the presence of adenosine triphosphate (ATP) hydrolyzing enzymes. ATPase in the mitotic spindle is discussed. There is a physiological evidence for dynein ATPase in mitotic spindles.
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Publisher Summary This chapter focuses on one aspect of the biochemistry of mitotic spindles—the presence of adenosine triphosphate (ATP) hydrolyzing enzymes. ATPase in the mitotic spindle is discussed. There is a physiological evidence for dynein ATPase in mitotic spindles.
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Biochemistry of the Mitotic Spindle
1979Publisher Summary The mitotic spindle consists of the chromatic and the achromatic figure. The chromatic figure consists of the chromosomes and includes their attachment points to the spindle, the kinetochores. The achromatic figure is more difficult to define.
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The Evolution of the Mitotic Spindle
1976Publisher Summary This chapter discusses the evolution of the mitotic spindle. The recounting of the evolutionary past of the mitotic processes of chromosome movement would entail tracing a gradual shift from membranes to micros as the primary producer of forces for chromosome movement.
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Mescaline as a mitotic spindle inhibitor
Nature, 1976COLCHICINE and its methyl derivative colcemid not only inhibit microtubule self-assembly1 but also affect fast transport in nerve2. A report that mescaline likewise inhibits the rapid component of axoplasmic transport in nerve3, led us to investigate the effects of this drug on mitosis, and on purified microtubule protein (tubulin4).
C M, Harrisson, B M, Page, H M, Keir
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Molecular components of the mitotic spindle
BioEssays, 1992AbstractMitotic spindles constitute the machinery responsible for equidistribution of the genetic material into each daughter cell during cell division. They are transient and hence quite labile structures, changing their morphology even while performing their function. Biochemical, immunological and genetic analyses of mitotic cells have allowed us to
R, Kuriyama, C, Nislow
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Polarity of microtubules of the mitotic spindle
Journal of Molecular Biology, 1978Abstract Microtubules are polar structures that grow preferentially at one end. Measurement of their rate of directional growth can be used as a polarity indicator to determine their orientation with respect to a nucleation site. The results are interpreted to signify that the microtubules originating from the centrosomes and chromosomes of the ...
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The regulation of mitotic spindle function
Biochemistry and Cell Biology, 1988The process of mitosis includes a series of morphological changes in the cell in which the directional movements of chromosomes are the most prominent. The presence of a microtubular array, known as the spindle or mitotic apparatus, provides at least a scaffold upon which these movements take place.
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