Results 11 to 20 of about 4,204 (164)

GC–MS and FTIR Characterization of Bioactive Compounds in Aqueous Extracts of Terminalia laxiflora Root and Mitragyna inermis Stem Bark

Journal of Chemistry
The contribution of medicinal plants in healthcare delivery has been acknowledged due to the numerous plant chemicals with health-promoting properties.
Sylvenus Aguree, Samson Abah Abagale, Isaac Sackey   +2 more
doaj   +2 more sources

The 730 nm Picosecond Titanium Sapphire Laser for Treatment of Kratom-Induced Hyperpigmentation. [PDF]

Lasers Surg Med
ABSTRACT Objectives This case series reports the use of the 730‐nm picosecond titanium‐sapphire laser in the treatment of kratom‐induced hyperpigmentation, a dermatological side effect associated with the use of Mitragyna speciosa, which remains poorly understood. Methods A series of patients with kratom‐induced hyperpigmentation were treated using the
Alhadyani AA, Samaan C, Munavalli GS.
europepmc   +2 more sources

The cellular toxicology of mitragynine, the dominant alkaloid of the narcotic-like herb, Mitragyna speciosa Korth [PDF]

, 2015
Mitragyna speciosa Korth (Kratom), a herb of the Rubiaceae family is indigenous in southeast Asia mainly in Malaysia and Thailand. It is used as an opium substitute and has been increasingly abused by drug addicts in Malaysia.
Gooderham, NJ, Holmes, E, Saidin, NA, Takayama, H   +3 more
core   +5 more sources

Kratom use disorder as a gateway to an opioid use disorder

European Psychiatry, 2023
Introduction Kratom (Mitragyna speciosa) is a psychoactive substance native to Thailand and Southeast Asia with stimulant-like effects at lower doses and opioid-like effects at higher doses.
A. C. Borges, D. Machado
doaj   +1 more source

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S, Orsolini, L, Pichini, S., Rotolo, Mc, Schifano, F, Tittarelli, R   +5 more
core   +1 more source

Sedative, cognitive impairment and anxiolytic effects of acute Mitragyna speciosa in rodents [PDF]

, 2013
Mitragyna speciosa, a plant from Rubiaceae family, was reported to have an opium-like effect and their coca-like stimulative ability to combat fatigue and enhance tolerance to hard work.
Adzhar, Muhammad Farhan, Amom, Zulkhairi, Baharuldin, Mohamad Taufik Hidayat, Fakurazi, Sharida, Mat Taib, Che Norma, Md Akim, Abdah, Md Rasul, Mohd Saifuddin, Mohd Moklas, Mohamad Aris, Muhamamd Yusof, Muhammad Khairulasraf, Suliman, Noor Azuin, Zakaria, Fatin Nadzirah   +10 more
core   +1 more source

7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]

, 2019
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael, Gassaway, Madalee M., Grinnell, Steven G., Javitch, Jonathan A., Kruegel, Andrew C., Langreck, Cory, Le Rouzic, Valerie, Majumdar, Susruta, Pasternak, Gavril W., Pekarskaya, Elizabeth A., Pintar, John E., Sames, Dalibor, Uprety, Rajendra   +12 more
core   +3 more sources

Agro-waste: a potential fermentation substrate for Penicillium chrysogenum [PDF]

, 2009
Common agro-wastes found in Lagos, Nigeria (cassava shavings, corncob, sawdust, and sugarcane pulp) were compared with glucose and lactose as fermentation substrates for Penicillium chrysogenum PCL501.
Chinedu, S. N., Okafor, U. A., Okochi, V. I., Onyegeme-Okerenta, B. M.   +3 more
core   +2 more sources

In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs)

Molecules, 2010
In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in
Sharif Mahsufi Mansor, Mohd Ikram Mohd Said, Surash Ramanathan, Mohd Nizam Mordi, Sabariah Ismail, Juzaili Azizi   +5 more
doaj   +1 more source

Association between kratom (Mitragyna speciosa) use and metabolic syndrome

Heliyon, 2022
Background and aims: There are evidence about effects of kratom (Mitragyna speciosa) use on parameters related to metabolic syndrome (MetS). The present study aimed to determine the association between kratom use and MetS.
Aroon La-up, Paleeratana Wongrith, Wiraphon Chaichan, Apinun Aramrattana, Udomsak Saengow   +4 more
doaj   +1 more source