Results 101 to 110 of about 2,942 (230)

Drogas legales emergentes: marihuana sintética, kratom, salvia divinorum, metoxetamina y los derivados de la piperazina [PDF]

, 2015
A pesar de su amplia oferta y disponibilidad a través de internet, muchas de las drogas de abuso emergentes siguen siendo desconocidas para un gran número de médicos y profesionales sanitarios.
Aliño, Marta, Espert Tortajada, Raúl, Gadea Domenech, Marien, Oltra Cucarella, Javier, Pérez San Miguel, Joana   +4 more
core  

Kratom (Mitragyna speciosa): ¿droga emergente o bala mágica? [PDF]

, 2013
En los últimos años, un número indeterminado y creciente de sustancias con actividad psicotrópica están siendo introducidas en contextos recreativos a través del mercado tecnológico que suponen internet y las nuevas tecnologías, tratando de franquear ...
Giner García, Ricardo, López Briz, Eduardo   +1 more
core  

MITRAGYNINE PERCENTAGES OF VARIOUS KRATOM VARIANTS SEIZED IN INDONESIA: A QUANTITATIVE ANALYSIS USING LIQUID CHROMATOGRAPHY-PHOTO DIODE ARRAY DETECTOR [PDF]

, 2021
Objective: This study details the determination of mitragynine in various kratom samples using the thin-layer chromatography (TLC) technique and validation of analytical methods for quantifying the concentration of mitragynine in various kratom samples ...
ARFIYANI, ERI, LALANGI, CHRISTIEN ANDRIYANI, MAULIDA, ERLANA NINDYA, NINGTIAS, WIDIANTI, TANTI   +4 more
core   +1 more source

An In Vitro Examination of Whether Kratom Extracts Enhance the Cytotoxicity of Low-Dose Doxorubicin against A549 Human Lung Cancer Cells

Molecules
Doxorubicin is an effective chemotherapeutic agent in the treatment of solid hematological and non-hematological carcinoma. However, its long-term usage could result in side effects, such as cardiomyopathy, chronic heart failure, neurotoxicity and cancer
Asep Bayu, Siti Irma Rahmawati, Firmansyah Karim, Jonathan Ardhianto Panggabean, Dasilva Primarindu Nuswantari, Dwi Wahyu Indriani, Peni Ahmadi, Rendi Witular, Ni Luh Putu Indi Dharmayanti, Masteria Yunovilsa Putra   +9 more
doaj   +1 more source

Adverse Events Related to Kratom Discontinuation and the Utilization of Prescribed Medications During Hospitalization: A 4-year Retrospective Study in Thanyarak Songkhla Hospital, Thailand

Journal of Health Science and Medical Research (JHSMR)
Objective: The purpose of this study was to investigate adverse events related to kratom cessation and the utilization of prescribed medications during hospitalization.
Sirima Sitaruno, Juraithip Wungsintaweekul, Tanatape Wanishayakorn, Tharin Kanjanasintou, Nattrawee Srisai, Chanocknun Kongruen, Chawisa Chaimongkon, Saodaro Sodadis, Thanurat Putthachat   +8 more
doaj   +1 more source

Drug Vaping: From the Dangers of Misuse to New Therapeutic Devices. [PDF]

, 2016
Users of e-cigarettes are unwitting volunteers participating in a worldwide epidemiological study. Because of the obvious benefits of e-cigarettes compared with traditional cigarette smoking, these electronic devices have been introduced all around the ...
Varlet, V.
core   +2 more sources

Kratom safety and toxicology in the public health context: research needs to better inform regulation

Frontiers in Pharmacology
Although kratom use has been part of life for centuries in Southeast Asia, the availability and use of kratom in the United States (US) increased substantially since the early 2000s when there was little information on kratom pharmacology, use patterns ...
Jack E. Henningfield, Jack E. Henningfield, Oliver Grundmann, Marilyn A. Huestis, Kirsten E. Smith   +4 more
doaj   +1 more source

Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents

Molecules, 2018
The co-use of conventional drug and herbal medicines may lead to herb-drug interaction via modulation of drug-metabolizing enzymes (DMEs) by herbal constituents.
Nurul Huda Abdullah, Sabariah Ismail
doaj   +1 more source

Kratom: a dangerous player in the opioid crisis

Journal of Community Hospital Internal Medicine Perspectives, 2018
Kratom use as a herbal supplement is on the rise in the United States, with reported medical outcomes and lethal effects suggesting a public health threat.
Khadija Tayabali, Colin Bolzon, Paul Foster, Janki Patel, Mohammad Omar Kalim   +4 more
doaj   +1 more source

Effects of Itraconazole on Pharmacokinetics of Mitragynine and 7-Hydroxymitragynine in Healthy Volunteers.

ACS Pharmacology & Translational Science
CYP3A4-mediated metabolic conversion of mitragynine to 7-hydroxymitragynine (7OH) has been demonstrated in human liver microsomes, and in rodents. Pharmacokinetics (PK) of mitragynine and 7OH in humans is still limited.
Pooja Mongar, Amit Jaisi, Thammasin Inkviya, J. Wungsintaweekul, K. Wiwattanawongsa   +4 more
semanticscholar   +1 more source