Results 81 to 90 of about 2,942 (230)

Seasonal and Geographic Variation in Alkaloid Content of Kratom (Mitragyna speciosa (Korth.) Havil.) from Thailand

open access: yesPlants, 2023
The objective of this study was to obtain data on the distribution of alkaloids in kratom plants grown in Thailand. Two collections were performed, covering the southern, central, and northern regions of Thailand and different seasons.
Narumon Sengnon   +9 more
doaj   +1 more source

Novel psychoactive substances of interest for psychiatry [PDF]

open access: yes, 2015
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John   +3 more
core   +1 more source

Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models

open access: yesJournal of Applied Toxicology, Volume 44, Issue 8, Page 1236-1245, August 2024.
Abstract Botanicals contain complex mixtures of chemicals most of which lack pharmacokinetic data in humans. Since physicochemical and pharmacokinetic properties dictate the in vivo exposure of botanical constituents, these parameters greatly impact the pharmacological and toxicological effects of botanicals in consumer products.
Yitong Liu   +5 more
wiley   +1 more source

Variations in mitragynine content in the naturally growing Kratom (Mitragyna speciosa) population of Thailand

open access: yesFrontiers in Plant Science, 2022
We analyzed the content of mitragynine (MG) found in kratom leaves (Mitragyna speciosa) and the influence of different environmental conditions (air and soil variables) on the yield in various regions of Thailand.
Nisa Leksungnoen   +11 more
doaj   +1 more source

Broad evidence of xylazine in the UK illicit drug market beyond heroin supplies: Triangulating from toxicology, drug‐testing and law enforcement

open access: yesAddiction, Volume 119, Issue 7, Page 1301-1309, July 2024.
Abstract Background and aims Xylazine is a non‐opioid sedative which has spread rapidly throughout the US illicit drug supply. This study aimed to describe the spread of xylazine throughout the UK illicit drug supply. Methods Xylazine detections in human biological samples were collated from toxicology laboratories operating in the United Kingdom with ...
Caroline S. Copeland   +8 more
wiley   +1 more source

Mitragyna speciosa: Opioid Addiction Treatment and Risk of Use

open access: yesJPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022
Kratom (Mitragyna speciosa (Korth.) Havil.) is a plant that originated from the rainforest in Southeast Asia, mainly grows in Thailand, Malaysia, and Indonesia. Kratom has been used traditionally as an herbal remedy for the treatment of various illnesses.
Azka Muhammad Rusydan   +2 more
doaj   +1 more source

Uji Efek Sedatif Fraksi Etanol Daun Kratom (Mitragyna Speciosa Korth.) Pada Mencit Jantan Galur Balb/c [PDF]

open access: yes, 2013
Kratom (Mitragyna speciosa Korth.) is one of traditional medical plant that canproduces both stimulant effects (in low doses) and sedative effects (in high doses).
Ridayani, Y. (Yeni)
core   +1 more source

User Experiences of Development of Dependence on the Synthetic Cannabinoids, 5f-AKB48 and 5F-PB-22, and Subsequent Withdrawal Syndromes [PDF]

open access: yes, 2017
Emergence of synthetic cannabinoids (SCBs) in herbal smoking mixtures is a public health concern. New SCB’s such as 5f-AKB48 and 5F-PB-22 have been detected in French seizures and in sudden death post mortems in the US.
A Grigoryev   +83 more
core   +1 more source

Neurobiology of Kratom and its main alkaloid mitragynine

open access: yesBrain Research Bulletin, 2016
Kratom or its main alkaloid, mitragynine is derived from the plant Mitragyna speciosa Korth which is indigenous to Southeast Asian countries. This substance has become widely available in other countries like Europe and United States due to its opium- and coca-like effects. In this article, we have reviewed available reports on mitragynine and other M.
Farah W, Suhaimi   +6 more
openaire   +2 more sources

Trends and challenges in the use of drugs as forensic evidence: A scientometric approach to map the current literature

open access: yesWIREs Forensic Science, Volume 6, Issue 2, March/April 2024.
Common keywords listed in the references cited in the INTERPOL IFSMS reports (1991–2022). Abstract The rapid increase in the production and distribution of illicit drugs has led to vast amounts of data being generated through research and other publications, making it difficult to effectively distill and analyze current and emerging trends. The present
Caitlyn Norman   +6 more
wiley   +1 more source

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