Results 31 to 40 of about 24,579 (198)

Cannabidiol affects MK-801-induced changes in the PPI Learned Response of Capuchin Monkeys (Sapajus spp.) [PDF]

open access: yes, 2017
There are several lines of evidence indicating a possible therapeutic action of cannabidiol (CBD) in schizophrenia treatment. Studies with rodents have demonstrated that CBD reverses MK-801 effects in prepulse inhibition (PPI) disruption, which may ...
Barros, Marília   +4 more
core   +1 more source

Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex [PDF]

open access: yes, 2013
El pdf del artículo es la versión post-print.The systemic administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists has been considered as a pharmacological model of schizophrenia.
Adell, Albert   +2 more
core   +2 more sources

Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801.

open access: yesPLoS ONE, 2015
MK-801, also known as dizocilpine, is a noncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms.
Wenjuan Yu   +5 more
doaj   +1 more source

FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801 [PDF]

open access: yes, 2013
BACKGROUND: Accumulating evidence has suggested the importance of glutamate signaling in cancer growth, yet the signaling pathway has not been fully elucidated.
Fuminori Yamaguchi   +6 more
core   +1 more source

Agmatine-attenuated cognitive and social deficits in subchronic MK-801 model of schizophrenia in rats

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
INTRODUCTION: Schizophrenia is one of the most severe psychiatric disorders with about 1% prevalence. It has been proved that glutamatergic N-methyl-d-aspartate (NMDA) receptor antagonists such as MK-801 and phencyclidine cause schizophrenia-like ...
Gokhan Unal, Alpay Ates, Feyza Aricioglu
doaj   +1 more source

Data on analysis of MK-801 bioavailability in mouse plasma and brain tissue by ultra-performance liquid chromatography-tandem mass spectrometry

open access: yesData in Brief, 2019
MK-801, a N-methyl-d-aspartate receptor antagonist, is widely used in animal preclinical experiments to induce memory and learning impairments and schizophrenia-like behavior.
Baiba Svalbe   +7 more
doaj   +1 more source

Interactions of Cholecystokinin and Glutamatergic Systems in Feeding Behavior of Neonatal Chickens [PDF]

open access: yesArchives of Razi Institute, 2022
This study aimed to assess the possible feeding behavior alterations by central interactions of cholecystokinin (CCK) and glutamatergic systems in neonatal chickens.
M Jelokhani   +3 more
doaj   +1 more source

MARKETING ACTIVITIES DURING THE INNOVATION PROCESS: INTERACTION OF RESEARCH AND DEVELOPMENT [PDF]

open access: yes, 2012
According to the aberrant-salience hypothesis, attribution of motivational salience is severely disrupted in patients with schizophrenia. To provide a translational approach for investigating underlying mechanisms, neural correlates of salience ...
Habel, Ute   +3 more
core   +1 more source

An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine [PDF]

open access: yes, 2010
Rationale—Research using a drug discriminated goal-tracking (DGT) task showed that the Nmethyl- D-aspartate (NMDA) channel blocker MK-801 (dizocilpine) reduced the nicotine-evoked conditioned response (CR).
Bevins, Rick A.   +3 more
core   +4 more sources

Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats

open access: yesFrontiers in Behavioral Neuroscience, 2019
MK-801, also known as dizocilpine, is a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms. Our previous study showed that brain-derived neurotrophic factor (BDNF) signaling was upregulated in ...
Wenjuan Yu   +12 more
doaj   +1 more source

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