Results 81 to 90 of about 246,934 (340)
Frontiers in Molecular Biosciences, 2022 Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate the turnover of extracellular matrix (ECM) components. Gross and La Piere discovered MMPs in 1962 during an experiment on tissue samples from a tadpole’s tail.
Sabeena Mustafa +2 more
doaj +1 more source
Hierarchical Clustering of Serum MMPs.
, 2013 Clustering of MMPs in the cohort, N = 193 showed that MMP3 and MMP-12 clustered together.
Ghislaine C. Echevarria (471367) +7 more
core +1 more source
One‐Step Curcumin‐Mediated Multiphoton Lithography for Bioactive 3D Scaffolds
Advanced Functional Materials, EarlyView.Curcumin‐mediated multiphoton lithography enables one‐step fabrication of highly architected complex gelatin methacryloyl scaffolds by exploiting curcumin as a multifunctional bioactive photoinitiator. The resulting 3D structures support mesenchymal stem cell adhesion, proliferation, and migration, while exhibiting dual antibacterial activity through ...
Myrto Charitaki +7 more
wiley +1 more source
Metalloproteinases and Hypertrophic Cardiomyopathy: A Systematic Review
Biomolecules, 2023 Hypertrophic cardiomyopathy (HCM) is a genetic condition determined by an altered collagen turnover of the extracellular matrix. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are abnormally released in patients with HCM.
Giuseppe Filiberto Serraino +8 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira +8 more
wiley +1 more source
Effect of simvastatin on the SIRT2/NF-κB pathway in rats with acute pulmonary embolism
Pharmaceutical Biology, 2018 Context: Statins have been widely used in acute pulmonary embolism (APE), while simvastatin has been well-established for the prevention of pulmonary hypertension, which was supposed to be an attractive recommendation for APE treatment.
Zhi-Yao Wu, Hui Li, Yong-Jun Tang
doaj +1 more source
Frontiers in Microbiology, 2018 While multicellular magnetotactic prokaryotes (MMPs) are ubiquitous in marine environments, the diversity of MMPs in sediments of coral reef ecosystems has rarely been reported. In this study, we made an investigation on the diversity and characteristics
Zhaojie Teng +20 more
doaj +1 more source
Marine Drugs, 2015 Fucoidan, a heparin-like sulfated polysaccharide, is rich in brown algae. It has a wide assortment of protective activities against cancer, for example, induction of hepatocellular carcinoma senescence, induction of human breast and colon carcinoma ...
Tse-Hung Huang +8 more
semanticscholar +1 more source
Combined Effects of MMP-7, MMP-8 and MMP-26 on the Risk of Ischemic Stroke [PDF]
Journal of Clinical Medicine, 2019 Ischemic stroke (IS) is multifactorial causation combining with traditional cardiovascular disease (CVD) and genetic risk factors. Combined effects of MMP-7, MMP-8 and MMP-26 on the risk of IS remain incompletely understood. We aimed to assess individual and joint effects for IS risk by weighted genetic risk score (wGRS) from these three genes and ...
Hsieh, Fang-I +6 more
openaire +2 more sources
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
Advanced Healthcare Materials, EarlyView.The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source