Results 121 to 130 of about 3,600,199 (198)

Performances of the rapid polymyxin Acinetobacter and Pseudomonas tests for colistin susceptibility testing [PDF]

, 2019
Owing to the emergence of colistin resistance in nonfermenting Gram negative bacteria, reliable and rapid techniques for testing colistin susceptibility are needed.
Lescat, Mathilde, Poirel, L., Nordmann, P., Lescat, M., Jayol, A., Jayol, Aurélie, Nordmann, Patrice, Poirel, Laurent   +7 more
core   +1 more source

Development and validation of a high-performance liquid chromatography-fluorescence detection method for the accurate quantification of colistin in human plasma

, 2017
Recently, colistin has become one of the most important drugs for treating infections caused by multidrug-resistant Gram-negative bacteria. Therapeutic drug monitoring is recommended to ensure the safety and efficacy of colistin and to improve clinical ...
郭錦樺;孫幸筠;林淑文, Chepyala, Divyabharathi;Tsai, I-Lin;Sun, Hsin-Yun;Lin, Shu-Wen;Kuo, Ching-Hua   +1 more
core   +1 more source

Combination of Colistin and Azidothymidine Demonstrates Synergistic Activity against Colistin-Resistant, Carbapenem-Resistant Klebsiella pneumoniae

, 2020
Carbapenem-resistant Enterobacteriaceae (CRE) is listed as an urgent threat by the World Health Organization because of the limited therapeutic options, rapid evolution of resistance mechanisms, and worldwide dissemination.
Ya-Ting Chang, Ya-Ju Hsieh, Sheng-Fan Wang, Po-Liang Lu, Liang-Chun Wang, Sung-Pin Tseng, Tsung-Ying Yang, Shang-Yi Lin   +7 more
core   +1 more source

Dissemination and Mechanism for the MCR-1 Colistin Resistance.

PLoS Pathogens, 2016
Polymyxins are the last line of defense against lethal infections caused by multidrug resistant Gram-negative pathogens. Very recently, the use of polymyxins has been greatly challenged by the emergence of the plasmid-borne mobile colistin resistance ...
Rongsui Gao, Yongfei Hu, Zhencui Li, Jian Sun, Qingjing Wang, Jingxia Lin, Huiyan Ye, Fei Liu, Swaminath Srinivas, Defeng Li, Baoli Zhu, Ya-Hong Liu, Guo-Bao Tian, Youjun Feng   +13 more
doaj   +1 more source

Induction of colistin resistance and environmental toxicity assessment in Escherichia coli.

PLoS ONE
The rise of Antimicrobial Resistance (AMR) among diverse microbial groups presents a growing threat to global public health. Colistin has become a last-line therapeutic option against multidrug-resistant Enterobacteriaceae.
Thalita Hellen Nunes Lima, Mariana de Souza, Jennifer Machado Soares, Kate Cristina Blanco, E Vanderlei Salvador Bagnato   +4 more
doaj   +1 more source

Determination of Colistin Resistance in Clinical Isolates from Healthcare Facilities in Mthatha and Surrounding Areas

Antibiotics
Background: Antimicrobial resistance (AMR) is a global threat in the public healthcare sector. The emergence of carbapenem-resistant Enterobacterales (CRE) has become a serious public health threat in South Africa. The spread of CRE has led to the use of
Silindokuhle Ndlela, Ravesh Singh, Sandeep Vasaikar   +2 more
doaj   +1 more source

Multicenter prospective study on the prevalence of colistin resistance in Escherichia coli: relevance of mcr-1-positive clinical isolates in Lombardy, Northern Italy

, 2018
Luigi Principe,1 Aurora Piazza,2,3 Carola Mauri,1 Adriano Anesi,4 Silvia Bracco,5 Gioconda Brigante,6 Erminia Casari,7 Carlo Agrappi,8 Mariasofia Caltagirone,2 Federica Novazzi,2 Roberta Migliavacca,2 Laura Pagani,2 Francesco Luzzaro1 1Microbiology and ...
Anesi A, Migliavacca R, Brigante G, Bracco S, Principe L, Novazzi F, Agrappi C, Caltagirone M, Luzzaro F, Mauri C, Piazza A, Pagani L, Casari E   +12 more
core  

Triazole Derivatives as Potential MCR-1 Inhibitors: A Promising Approach to Overcome Colistin Resistance [PDF]

BACKGROUND/AIMS: Colistin, a last-resort antibiotic, is crucial in treating multidrug-resistant Gram-negative infections. However, the rise of colistin resistance, particularly due to plasmid-mediated MCR-1 genes, poses a significant challenge.
Emine Erdağ, Cenk Serhan Özverel, Cemile Bağkur   +2 more
core   +1 more source

Mobile colistin resistance mcr-4.3- and mcr-4.6-harbouring plasmids in livestock- and human-retrieved Enterobacterales in the Netherlands. [PDF]

JAC Antimicrob Resist, 2023
Jamin C, Brouwer MSM, Veldman KT, Beuken E, Witteveen S, Landman F, Heddema E, Savelkoul PHM, van Alphen L, Hendrickx APA, Dutch CPE Surveillance Study Group .   +10 more
europepmc   +1 more source

First report of the mcr-1 gene in colistin-resistant Klebsiella pneumoniae in a tertiary care hospital in Tunisia

BMC Infectious Diseases
Background Colistin resistance mediated by mcr genes poses a critical threat to antimicrobial therapy, particularly in multidrug-resistant Klebsiella pneumoniae. While mcr-1 has been previously identified in clinical Escherichia coli in Tunisia, no human
Manel Ennaceur, Hamza Ben Mesbeh, Othman Bacha, Imene Ouzari, Farouk Barguellil, Sonia Chouaieb   +5 more
doaj   +1 more source