Results 111 to 120 of about 3,785,189 (191)

Colistin resistance in ESBL- and Carbapenemase-producing Escherichia coli and Klebsiella pneumoniae clinical isolates in Cambodia

Journal of Global Antimicrobial Resistance
: Objectives: Despite the critical importance of colistin as a last-resort antibiotic, limited studies have investigated colistin resistance in human infections in Cambodia.
Mallorie Hide, Soda Meng, Sokleaph Cheng, Anne-Laure Bañuls, Santy KY, Chantana YAY, Denis Laurent, Gauthier Delvallez   +7 more
doaj   +1 more source

Triazole Derivatives as Potential MCR-1 Inhibitors: A Promising Approach to Overcome Colistin Resistance [PDF]

BACKGROUND/AIMS: Colistin, a last-resort antibiotic, is crucial in treating multidrug-resistant Gram-negative infections. However, the rise of colistin resistance, particularly due to plasmid-mediated MCR-1 genes, poses a significant challenge.
Emine Erdağ, Cenk Serhan Özverel, Cemile Bağkur   +2 more
core   +1 more source

Resistance to Colistin Mediated by mcr-1 among Multidrug Resistant Gram Negative Pathogens at a Tertiary Care Hospital, Egypt

, 2020
Colistin is considered the last option for treatment of infections caused by Multidrug Resistant (MDR) Gram negative pathogens. The mcr-1 gene could transfer the resistance to colistin between different species.
Noha Alaa Eldin Fahim, Nagwa M Abo El Magd, Nagwa M. Abo El Magd, Marwa Shabban, Karim Montasser   +4 more
core   +1 more source

Frequency of colistin and fosfomycin resistance in carbapenem-resistant Enterobacteriaceae from a tertiary care hospital in Karachi

, 2017
Salima Qamar, Najma Shaheen, Sadia Shakoor, Joveria Farooqi, Kauser Jabeen, Rumina Hasan Clinical Microbiology, Department of Pathology And Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan Introduction ...
Farooqi J, Hasan R, Jabeen K, Shakoor S, Qamar S, Shaheen N   +5 more
core  

Plasmid-mediated colistin resistance in animals: current status and future directions

, 2017
Colistin, a peptide antibiotic belonging to the polymyxin family, is one of the last effective drugs for the treatment of multidrug resistant Gram-negative infections.
Jian Sun, Ximin Zeng, Jun Lin, Xiao-Ping Liao, Ya-Hong Liu, Xing-Ping Li   +5 more
core   +1 more source

Dissemination and Mechanism for the MCR-1 Colistin Resistance.

PLoS Pathogens, 2016
Polymyxins are the last line of defense against lethal infections caused by multidrug resistant Gram-negative pathogens. Very recently, the use of polymyxins has been greatly challenged by the emergence of the plasmid-borne mobile colistin resistance ...
Rongsui Gao, Yongfei Hu, Zhencui Li, Jian Sun, Qingjing Wang, Jingxia Lin, Huiyan Ye, Fei Liu, Swaminath Srinivas, Defeng Li, Baoli Zhu, Ya-Hong Liu, Guo-Bao Tian, Youjun Feng   +13 more
doaj   +1 more source

Induction of colistin resistance and environmental toxicity assessment in Escherichia coli.

PLoS ONE
The rise of Antimicrobial Resistance (AMR) among diverse microbial groups presents a growing threat to global public health. Colistin has become a last-line therapeutic option against multidrug-resistant Enterobacteriaceae.
Thalita Hellen Nunes Lima, Mariana de Souza, Jennifer Machado Soares, Kate Cristina Blanco, E Vanderlei Salvador Bagnato   +4 more
doaj   +1 more source

Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015

, 2020
Antimicrobial resistance of pathogenic microorganisms is an emerging public health concern. Intensive use of antibiotics in food animals might increase antimicrobial resistance in foodborne pathogens. Colistin is a last resort antibiotic for treatment of
Güzel, Mustafa, Avşaroğlu, M Dilek, Soyer, Yeşim   +2 more
core  

Determination of Colistin Resistance in Clinical Isolates from Healthcare Facilities in Mthatha and Surrounding Areas

Antibiotics
Background: Antimicrobial resistance (AMR) is a global threat in the public healthcare sector. The emergence of carbapenem-resistant Enterobacterales (CRE) has become a serious public health threat in South Africa. The spread of CRE has led to the use of
Silindokuhle Ndlela, Ravesh Singh, Sandeep Vasaikar   +2 more
doaj   +1 more source

The clue is in the lipid A: Rapid detection of colistin resistance - Fig 1

, 2020
(Left column) Structures of the native (top) and modified (middle and bottom) lipid A portion of the Escherichia coli LPS. L-Ara4N (marked in red) and PEtN (marked in blue) modifications to lipid A cause resistance to polymyxin antibiotics.
Markus Kostrzewa (271157), Gerald Larrouy-Maumus (4395031), R. Christopher D. Furniss (2809279), Despoina A. I. Mavridou (8693736)   +3 more
core   +1 more source