Results 111 to 120 of about 3,600,199 (198)

NMCR-6, a novel nonmobile colistin resistance gene in Vibrio bacteria: full characterization and global perspective

Decoding Infection and Transmission
Objective: Amid rising bacterial resistance, polymyxins are a critical last resort against multidrug-resistant Gram-negative infections. Understanding and predicting the emergence of novel, nonmobile colistin resistance (NMCR) genes are essential to ...
Xinkun Zhu, Junyang Ma, Renge Hu, Qing Yang, Lei Yang, Shu Li, Yuanhuan Kang, Zhenlin Liang, Hany M. Elsheikha, Wei Cong   +9 more
doaj   +1 more source

Frequency of colistin and fosfomycin resistance in carbapenem-resistant Enterobacteriaceae from a tertiary care hospital in Karachi

, 2017
Salima Qamar, Najma Shaheen, Sadia Shakoor, Joveria Farooqi, Kauser Jabeen, Rumina Hasan Clinical Microbiology, Department of Pathology And Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan Introduction ...
Farooqi J, Hasan R, Jabeen K, Shakoor S, Qamar S, Shaheen N   +5 more
core  

Colistin Resistance in Aeromonas spp.

, 2021
The increase in the use of antimicrobials such as colistin for the treatment of infectious diseases has led to the appearance of Aeromonas strains resistant to this drug.
Cecilia Hernández-Cortez, Luis Uriel Gonzalez-Avila, Miguel Angel Loyola-Cruz, Juan Manuel Bello-López, Graciela Castro-Escarpulli   +4 more
core   +1 more source

Colistin-stimulated ROS production is significantly impaired by the presence of colistin resistance-conferring proteins (EptA/MCR-1/ICR-Mo).

, 2018
A & B Accumulation of hydrogen peroxide is boosted by colistin stress in E. coli. C & D The presence of plasmid-borne EptA inhibits colistin-induced production of hydrogen peroxide in E. coli.
Swaminath Srinivas (450675), Jingxia Lin (3365054), Youjun Feng (16133), Vishnu Goutham Kota (5216144), Wenhui Wei (176525), Zichen Tang (3602876), Shihua Wang (219946), Saif Ullah (2360377)   +7 more
core   +1 more source

First report of the plasmid-borne colistin resistance gene (mcr-1) in Proteus mirabilis isolated from a toddler in non-clinical settings

IDCases, 2019
We report the detection of a plasmid-borne mobile colistin-resistance-gene, mcr-1, in Proteus mirabilis, a known community and hospital pathogen, that was isolated from a toddler (2 years old) in the community in Lebanon.
Zaynab Hmede, Issmat I. Kassem
doaj   +1 more source

Resistance to Colistin Mediated by mcr-1 among Multidrug Resistant Gram Negative Pathogens at a Tertiary Care Hospital, Egypt

, 2020
Colistin is considered the last option for treatment of infections caused by Multidrug Resistant (MDR) Gram negative pathogens. The mcr-1 gene could transfer the resistance to colistin between different species.
Noha Alaa Eldin Fahim, Nagwa M Abo El Magd, Nagwa M. Abo El Magd, Marwa Shabban, Karim Montasser   +4 more
core   +1 more source

Colistin Resistance Mechanisms and Molecular Epidemiology of Enterobacter cloacae Complex Isolated from a Tertiary Hospital in Shandong, China [PDF]

Zaifeng Si,1,2,* Shengmei Zhao,3,* Yingying Hao,3 Qian Wang,3 Yanfa Zhong,2 Yue Liu,3 Ran Chen,3 Yan Jin,3 Zhiming Lu1,3 1Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan ...
Liu Y, Zhao S, Wang Q, Si Z, Lu Z, Hao Y, Zhong Y, Jin Y, Chen R   +8 more
core  

Involvement of hpap2 and dgkA Genes in Colistin Resistance Mediated by mcr Determinants

, 2020
Plasmid-mediated colistin resistance (mcr) determinants are challenging the efficacy of polymyxins against Gram-negative pathogens. Among 10 mcr genes described so far, the major determinants mcr-1 and mcr-3 are found closely linked to hpap2 or dgkA ...
Alberto Quesada, María Ugarte-Ruiz, Marta Hernández, Pedro Miguela-Villoldo, Lucas Domínguez, David Rodríguez-Lázaro, Alejandro Gallardo   +6 more
core   +1 more source

Colistin Resistance in Gram-Negative Bacteria: Mechanisms, Transmission, and Novel Intervention Strategies

Multidrug resistance (MDR) in Gram-negative bacteria is a global issue and needs to be addressed urgently. MDR can emerge through genetic mutations and horizontal gene transfer and deteriorate under antibiotic selective pressure.
Zeb, Shah, Hameed, Muhammad Fazal, Muhammad Fazal Hameed, Li, Ruichao, Patrick Butaye, Xiaoyu Lu, Shah Zeb, Butaye, Patrick, Haider Naqvi, Syed Zeeshan, Wang, Zhiqiang, Zhiqiang Wang, Shoaib, Muhammad, Nazir, Arzoo, Ikram, Sadia, Arzoo Nazir, Sadia Ikram, Ruichao Li, Lu, Xiaoyu, Muhammad Shoaib, Syed Zeeshan Haider Naqvi   +19 more
core   +1 more source

Identification of Genetic Alterations Associated with Acquired Colistin Resistance in Klebsiella pneumoniae Isogenic Strains by Whole-Genome Sequencing

, 2020
The present study was undertaken to find novel genes associated with colistin resistance in Klebsiella pneumoniae. Five colistin-resistant mutants were derived from four colistin-susceptible parental K.
Myeongjin Choi, Kwan Soo Ko
core   +1 more source