Results 91 to 100 of about 3,785,189 (191)

Phage-mediated colistin resistance in Acinetobacter baumannii

Aims: Antimicrobial resistance is a global threat to human health, and Acinetobacter baumannii is a paradigmatic example of how rapidly bacteria become resistant to clinically relevant antimicrobials. The emergence of multidrug-resistant A.
Lucidi, Massimiliano, Rampioni, Giordano, Artuso, Irene, Visaggio, Daniela, Leoni, Livia, Visca, Paolo, Imperi, Francesco, Capecchi, Giulia, Spagnoli, Cinzia   +8 more
core   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Mobile Colistin Resistance (MCR) Gene, Antimicrobial Resistance: A Global Public Health Threat

Bangladesh Journal of Medical Science, 2019
Abstract not available Bangladesh Journal of Medical Science Vol.19(1) 2020 p.5 ...
Tanzina Nusrat, Mainul Haque
openaire   +2 more sources

Antibacterial and Antibiofilm Activity of a Chemically Characterized Cinnamomum verum Bark Methanolic Extract Against Multidrug‐Resistant Bacteria: Preliminary Antibiotic–Interaction Screening and Exploratory Molecular Docking

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri, Sarra Elmsehli, Assia kenich, Mabrouk Horchani, Hanen Najjaa, Naima Najah, Hasan Aljohi, Mohammad Nasser Alkhrayef, Roberta Ascrizzi, Guido Flamini, Ibrahim O. Alanazi, Mozaniel Santana de Oliveira   +11 more
wiley   +1 more source

Antimicrobial resistance to colistin in neonates: epidemiological insights and public health implications in Nigeria – a mini review

Annals of Medicine
Introduction/Background Antimicrobial resistance (AMR) remains a critical global health issue, particularly in low- and middle-income countries like Nigeria.
Adewunmi Akingbola, Abiodun Christopher Adegbesan, Olaoluwa Olorunfemi, Kolade Adegoke, Kehinde Abereoje, Olajumoke Adewole, Victor Olamide Oluwasola, Somadila Igboanugo, Ademola Aiyenuro   +8 more
doaj   +1 more source

mcr‐Mediated Colistin Resistance in Escherichia coli: A One Health Review of Reported Prevalence Across Human, Animal, Food, and Environmental Sectors

Public Health Challenges, Volume 5, Issue 3, September 2026.
This One Health review maps the global prevalence of mcr‐mediated colistin resistance in Escherichia coli across human, animal, food, and environmental sectors. By tracking datasets across diverse geographic regions, the study highlights critical resistance hotspots, emphasizing the urgent need for integrated cross‐sectoral surveillance to limit global
Ferdous‐Ul‐Haque Joy, Tashfiya Zaman Mouree, Munny Das, Asma Kabir   +3 more
wiley   +1 more source

Colistin-resistance gene mcr in clinical carbapenem-resistant Enterobacteriaceae strains in China, 2014–2019

, 2020
To investigate whether introduction of colistin into the clinical settings selected colistin-resistant CRE, we performed molecular epidemiological study of 1868 CRE strains collected from different geographical locales in China during the period 2014 ...
Rong Zhang (44942), Edward Wai-Chi Chan (4356652), Qiaoling Sun (738882), Jiayue Lu (8376588), Sheng Chen (21971), Ning Dong (340660), Hong Huang (119275), Lingbin Shu (8376585)   +7 more
core   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, Volume 26, Issue 9, September 2026.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Antibacterial Efficacy of 6‐Gingerol Alone and in Combination With Enrofloxacin Against Multidrug‐Resistant Staphylococcus aureus Isolated From Goats

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Integrated mastitis screening effectively identified MRSA‐associated Staphylococcus aureus in goats, with the Surf Field Mastitis Test proving a reliable rapid diagnostic tool. Combination therapy of enrofloxacin and 6‐gingerol showed superior antibacterial activity, highlighting 6‐gingerol as a promising adjunct to combat antimicrobial‐resistant ...
Maria Khan, Arshad Zahoor, Shabana Naz, Caterina Losacco, Sohail Ahmad, Ibrahim A. Alhidary, Luciana Rossi, Rifat Ullah Khan, Huda A. Alqahtani   +8 more
wiley   +1 more source

Acinetobacter baumannii under Acidic Conditions Induces Colistin Resistance through PmrAB Activation and Lipid A Modification

, 2023
Colistin is a last-resort antimicrobial agent for treating carbapenem-resistant Acinetobacter baumannii infections. The activation of PmrAB by several environmental signals induces colistin resistance in Gram-negative bacteria.
Minsang Shin, Je-Chul Lee, Seong-Yong Park, Seong-Yeop Kim, Seo-Yeon Ko, Nayeong Kim   +5 more
core   +1 more source