Results 71 to 80 of about 3,600,199 (198)

Diversified mcr-1-Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota

mBio, 2016
Colistin is an ultimate line of refuge against multidrug-resistant Gram-negative pathogens. Very recently, the emergence of plasmid-mediated mcr-1 colistin resistance has become a great challenge to global public health, raising the possibility that ...
Huiyan Ye, Yihui Li, Zhencui Li, Rongsui Gao, Han Zhang, Ronghui Wen, George F. Gao, Qinghua Hu, Youjun Feng   +8 more
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Colistin-resistance gene mcr in clinical carbapenem-resistant Enterobacteriaceae strains in China, 2014–2019

, 2020
To investigate whether introduction of colistin into the clinical settings selected colistin-resistant CRE, we performed molecular epidemiological study of 1868 CRE strains collected from different geographical locales in China during the period 2014 ...
Rong Zhang (44942), Edward Wai-Chi Chan (4356652), Qiaoling Sun (738882), Jiayue Lu (8376588), Sheng Chen (21971), Ning Dong (340660), Hong Huang (119275), Lingbin Shu (8376585)   +7 more
core   +1 more source

Induction of proteome changes involved in the cloning of mcr-1 and mcr-2 genes in Escherichia coli DH5-α strain to evaluate colistin resistance

Journal of Global Antimicrobial Resistance
: Objectives: Plasmid genes, termed mobile colistin resistance-1 (mcr-1) and mobile colistin resistance-2 (mcr-2), are associated with resistance to colistin in Escherichia coli (E. coli).
Hadi Feizi, Maryam Alizadeh, Hadi Azimi, Ehsaneh Khodadadi, Fadhil S. Kamounah, Khudaverdi Ganbarov, Reza Ghotaslou, Mohammad Ahangarzadeh Rezaee, Hossein Samadi Kafil   +8 more
doaj   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Detection of Plasmid-Mediated Resistance against Colistin in Multi-Drug-Resistant Gram-Negative Bacilli Isolated from a Tertiary Hospital

, 2023
The aim of this study was to determine the prevalence of plasmid-mediated colistin resistance mcr-1 to mcr-5 genes among colistin and multi-drug-resistant Gram-negative bacilli strains isolated from patients in a tertiary hospital in Toluca, Mexico.
Laura Guadarrama-Monroy, José David Santiago-Luna, Reinaldo Pacheco-Vásquez, Humberto Navarrete-Salazar, Isabel Baltazar-Jiménez, Mario Galindo-Méndez, Devanhí Quintas-de la Paz   +6 more
core   +1 more source

Nonclonal Emergence of Colistin Resistance Associated with Mutations in the BasRS Two-Component System in Escherichia coli Bloodstream Isolates

mSphere, 2020
Infections by multidrug-resistant Gram-negative bacteria are increasingly common, prompting the renewed interest in the use of colistin. Colistin specifically targets Gram-negative bacteria by interacting with the anionic lipid A moieties of ...
Axel B. Janssen, Toby L. Bartholomew, Natalia P. Marciszewska, Marc J. M. Bonten, Rob J. L. Willems, Jose A. Bengoechea, Willem van Schaik   +6 more
doaj   +1 more source

Molecular Mechanisms of Colistin Resistance in Klebsiella pneumoniae in a Tertiary Care Teaching Hospital

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundOver the last two decades, the prevalence of colistin resistance among the members of Enterobacteriaceae has been increasing, particularly among Klebsiella pneumoniae isolates; this limits the potential use of colistin and leads to worsened ...
Yanling Liu, Yiqing Lin, Ziwen Wang, Niya Hu, Qiong Liu, Wenkai Zhou, Xiuzhen Li, Longhua Hu, Jian Guo, Xiaotian Huang, Lingbing Zeng   +10 more
doaj   +1 more source

Carriage of antimicrobial‐resistant E. coli in urban stray cats (Felis catus)

Australian Veterinary Journal, EarlyView.
Antimicrobial resistance (AMR) in Escherichia coli is a growing concern in both human and veterinary medicine, driven by the inappropriate use of antimicrobials. Companion animals may act as community reservoirs and sentinels for antimicrobial‐resistant bacteria due to their close contact with humans and other animals.
JS Kuan, S Mukerji, D Hampson, S Abraham
wiley   +1 more source

Colistin Resistance in Environmental Isolates ofAcinetobacter baumannii

, 2020
Although the molecular mechanisms of carbapenem resistance of environmental isolates ofAcinetobacter baumanniiare well described, data on the mechanisms of colistin resistance are scarce.
Jovčić, Branko, Hrenović, Jasna, Dekić, Svjetlana, Novović, Katarina   +3 more
core   +1 more source