Results 61 to 70 of about 3,785,189 (191)

Characteristics and genomic epidemiology of colistin-resistant Enterobacterales from farmers, swine, and hospitalized patients in Thailand, 2014–2017

BMC Infectious Diseases, 2023
Background Colistin is one of the last resort therapeutic options for treating carbapenemase-producing Enterobacterales, which are resistant to a broad range of beta-lactam antibiotics.
Adhiratha Boonyasiri, Lauren M. Brinkac, Elita Jauneikaite, Richard C. White, Chris Greco, Chakkraphong Seenama, Teerawit Tangkoskul, Kevin Nguyen, Derrick E. Fouts, Visanu Thamlikitkul   +9 more
doaj   +1 more source

Prevalence of colistin-resistant Escherichia coli in foods and food-producing animals through the food chain: A worldwide systematic review and meta-analysis

Heliyon
The purpose of this systematic review and meta-analysis was to summarize the available scientific evidence on the prevalence of colistin-resistant Escherichia coli strains isolated from foods and food-producing animals, the mobile colistin-resistant ...
Florencia Aylen Lencina, Matías Bertona, María Angeles Stegmayer, Carolina Raquel Olivero, Laureano Sebastián Frizzo, Jorge Alberto Zimmermann, Marcelo Lisandro Signorini, Lorena Paola Soto, María Virginia Zbrun   +8 more
doaj   +1 more source

The MCR-3 inside linker appears as a facilitator of colistin resistance

Cell Reports, 2021
Summary: An evolving family of mobile colistin resistance (MCR) enzymes is threatening public health. However, the molecular mechanism by which the MCR enzyme as a rare member of lipid A-phosphoethanolamine (PEA) transferases gains the ability to confer ...
Yongchang Xu, Haiyi Chen, Huimin Zhang, Saif Ullah, Tingjun Hou, Youjun Feng   +5 more
doaj   +1 more source

Colistin Resistance in Environmental Isolates of Acinetobacter baumannii

, 2020
Although the molecular mechanisms of carbapenem resistance of environmental isolates ofAcinetobacter baumanniiare well described, data on the mechanisms of colistin resistance are scarce.
Jovčić, Branko, Hrenovic, Jasna, Novovic, Katarina, Dekic, Svjetlana   +3 more
core   +1 more source

Definition of a Family of Nonmobile Colistin Resistance (NMCR‐1) Determinants Suggests Aquatic Reservoirs for MCR‐4

Advanced Science, 2019
Polymyxins, a family of cationic antimicrobial peptides, are recognized as a last‐resort clinical option used in the treatment of lethal infections with carbapenem‐resistant pathogens.
Huimin Zhang, Wenhui Wei, Man Huang, Zeeshan Umar, Youjun Feng   +4 more
doaj   +1 more source

Surveillance and Genomic Characterisation of Colistin-Resistant Gram-Negative Bacteria in the Drains of High-Risk Hospital Units

Journal of Global Antimicrobial Resistance
: Objective: The health care water environment, including sinks and drainage systems, can be a long-term reservoir of nosocomial pathogens. In this study, we aimed to investigate the presence of colistin-resistant Gram-negative (ColR-GN) bacteria in ...
Giuseppe Fleres, Alessia Mirabile, Mariëtte Lokate, John W.A. Rossen, Natacha Couto, Alexander W. Friedrich, Silvia García-Cobos   +6 more
doaj   +1 more source

The sRNA vvrr1 Modulates the VarS/VarA‐Csr System via LeuO to Regulate Biofilm Formation and Virulence in Vibrio alginolyticus

Animal Research and One Health, EarlyView.
vvrr1, a small RNA, post‐transcriptionally represses the transcriptional regulator LeuO, which directly inhibits the VarS/VarA two‐component system. This triggers a Csr cascade that relieves LuxO repression, ultimately modulating exopolysaccharide production to control biofilm formation and virulence in Vibrio alginolyticus.
Theerakamol Pengsakul, Lei Wen, Lingmin Zhao, Bei Huang, Jiang Zheng, Binfu Xu, Lixing Huang   +6 more
wiley   +1 more source

Diversified mcr-1-Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota

mBio, 2016
Colistin is an ultimate line of refuge against multidrug-resistant Gram-negative pathogens. Very recently, the emergence of plasmid-mediated mcr-1 colistin resistance has become a great challenge to global public health, raising the possibility that ...
Huiyan Ye, Yihui Li, Zhencui Li, Rongsui Gao, Han Zhang, Ronghui Wen, George F. Gao, Qinghua Hu, Youjun Feng   +8 more
doaj   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Induction of proteome changes involved in the cloning of mcr-1 and mcr-2 genes in Escherichia coli DH5-α strain to evaluate colistin resistance

Journal of Global Antimicrobial Resistance
: Objectives: Plasmid genes, termed mobile colistin resistance-1 (mcr-1) and mobile colistin resistance-2 (mcr-2), are associated with resistance to colistin in Escherichia coli (E. coli).
Hadi Feizi, Maryam Alizadeh, Hadi Azimi, Ehsaneh Khodadadi, Fadhil S. Kamounah, Khudaverdi Ganbarov, Reza Ghotaslou, Mohammad Ahangarzadeh Rezaee, Hossein Samadi Kafil   +8 more
doaj   +1 more source