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Colistin is a last-resort antibiotic for multidrug-resistant Gram-negative infections. Recently, the ninth allele of the mobile colistin resistance (mcr) gene family, designated mcr-9, was reported.
Ahmed Babiker +11 more
doaj +1 more source
An Overview of Mobile Colistin Resistance (mcr) Genes in Gram-Negative Bacilli. [PDF]
Yadav MV, Pawar S, Patil S.
europepmc +2 more sources
Due to the wide use of antibiotics, intensive aquaculture farms have been recognized as a significant reservoir of antibiotic resistomes. Although the prevalence of colistin resistance genes and multidrug-resistant bacteria (MDRB) has been documented ...
Zhao, Huijun +6 more
core +1 more source
Phenotypic and Genotypic Characterization of Colistin Resistance in Escherichia coli Isolated from Bovine Mastitis [PDF]
Mastitis is a global disease occurring in dairy cows, causing notable economic losses. Extensive use of antibiotics could allow the emergence of mobile antimicrobial resistance genes in mastitis-causing pathogens.
Mohamadhadi Zarei +5 more
doaj +1 more source
VIM-1-producing Enterobacter asburiae with mobile colistin resistance genes from wastewaters. [PDF]
Wastewaters are considered as important players in the spread of antimicrobial resistance, thus affecting the health of humans and animals. Here, we focused on wastewaters as a possible source of carbapenemase-producing Enterobacterales for the environment.A total of 180 presumptive coliforms from hospital and municipal wastewaters, and a river in the ...
Sukkar I, Valcek A, Dolejska M.
europepmc +5 more sources
Novel Plasmid-Mediated Colistin Resistance Gene
The mobile colistin resistance gene mcr-1 has attracted global attention, as it heralds the breach of polymyxins, one of the last-resort antibiotics for the treatment of severe clinical infections caused by multidrug-resistant Gram-negative bacteria.
Wenjuan Yin +9 more
doaj +1 more source
: Objectives: The continuing rise in infections caused by multidrug-resistant (MDR) bacteria is one of the most serious public-health issues in society today.
Masoud Dadashi +8 more
doaj +1 more source
The prevalence, diagnosis, and dissemination of mcr-1 in colistin resistance: Progress and challenge
Considered as the last defense line against Gram-negative bacteria, colistin is particularly effective against multiple drug-resistant bacteria such as multi-drug resistance (MDR) and carbapenem-resistant Enterobacteriaceae (CRE).
Jun Feng +7 more
doaj +1 more source
The global distribution and spread of the mobilized colistin resistance gene mcr-1 [PDF]
Abstract Colistin represents one of the very few available drugs for treating infections caused by carbapenem resistant Enterobacteriaceae (CRE). As such, the recent plasmid-mediated spread of the mobilized colistin resistance gene mcr-1 poses a significant public health threat ...
Wang, R +15 more
openaire +8 more sources
Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Zhuoren, Ling +5 more
openaire +2 more sources

