Results 51 to 60 of about 3,600,199 (198)
, 2021 Multidrug-resistant bacterial infections are becoming increasingly common, with only few last-resort antibiotics such as colistin available for clinical therapy.
Xiaoting Hua (435699) +5 more
core +1 more source
MCR-1 Confers Cross-Resistance to Bacitracin, a Widely Used In-Feed Antibiotic
mSphere, 2018 Extensive use of colistin in food animals is deemed a major driving force for the emergence and transmission of mcr-1. However, a non-colistin usage factor(s) contributing to mobile colistin resistance may also exist in animal production systems.
Fuzhou Xu +3 more
doaj +1 more source
Scientific Reports, 2023 AbstractS. 4,[5],12:i:-, a monophasic variant of S. enterica serovar Typhimurium, is an important multidrug resistant serovar. Strains of colistin-resistant S. 4,[5],12:i:- have been reported in several countries with patients occasionally had recent histories of travels to Southeast Asia. In the study herein, we investigated the genomes of S. 4,[5],12:
Sirirak Supa-amornkul +4 more
openaire +3 more sources
Evolutionary drivers of mobile colistin resistance
, 2022 Antibiotics are our strongest defence against disease causing bacteria. This makes the threat of widespread antibiotic resistance all the more concerning. Last-resort antibiotics such as colistin are especially important as they are effective against multiple-drug resistant pathogens.
openaire +1 more source
Mobile Plasmid Mediated Transition From Colistin-Sensitive to Resistant Phenotype in Klebsiella pneumoniae [PDF]
Frontiers in Microbiology, 2021 Multidrug-resistant bacteria, including carbapenem-resistant Klebsiella pneumoniae (CRKP), are becoming an increasing health crisis worldwide. For CRKP, colistin is regarded as “the last treatment option.” In this study, we isolated a clinical CRKP strain named as K. pneumoniae R10-341.
Baoyue Zhang +10 more
openaire +3 more sources
Colistin: A mainstay antibiotic for treatment of fatal Gram negative bacterial infections [PDF]
ERU Research JournalOur world is facing an enormous disaster due to spreading of the life-threatening bacterial infections, especially after the spread of multidrug-resistant Gram-negative bacteria (MDR-GNB), including those resistant to known antibiotics such as ...
Ahmed El-Khatib, Ahmed Basyony
doaj +1 more source
Global Challenges, 2021 Horizontal gene transfer facilitates the spread of antibiotic resistance genes, which constitutes a global challenge. However, the evolutionary trajectory of the mobile colistin resistome in bacteria is largely unknown. To investigate the coevolution and
Ruichao Li +7 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionWithin the 2007–2014 programme for the surveillance of antimicrobial resistance (AMR) in livestock in France, mcr-1 prevalence average in commensal Escherichia coli was found to be 5.9% in turkeys and 1.8% in broilers, indicating that mobile ...
Agnès Perrin-Guyomard +6 more
doaj +1 more source
eLife, 2022 Bacterial pathogens show high levels of chromosomal genetic diversity, but the influence of this diversity on the evolution of antibiotic resistance by plasmid acquisition remains unclear. Here, we address this problem in the context of colistin, a ‘last
Pramod K Jangir +7 more
doaj +1 more source
Silent spread of mobile colistin resistance gene mcr-9.1 on IncHI2 ‘superplasmids’ in clinical carbapenem-resistant Enterobacterales [PDF]
Clinical Microbiology and Infection, 2021 mcr-9.1 is a newly described mobile colistin resistance gene. We have noted its presence in multiple species of carbapenem-resistant Enterobacterales (CRE) from our institution. We aimed to determine the clinical features, genomic context and phenotypic impact of mcr-9.1 carriage in a series of patients between 2010 and 2019.We identified 32 patients ...
Nenad, Macesic +9 more
openaire +2 more sources