Results 11 to 20 of about 3,038,058 (339)

Molecular identification of pathogenic fungi [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2008
Systemic fungal infections represent a major cause of morbidity and mortality in immunocompromised patients. The ever-increasing number of yeast species associated with human infections that are not covered by conventional identification kits, and the fact that moulds isolated from deep infections are frequently impossible to identify using classical ...
Andrew M, Borman   +3 more
openaire   +2 more sources

Molecular Formula Identification with SIRIUS [PDF]

open access: yesMetabolites, 2013
We present results of the SIRIUS2 submission to the 2012 CASMI contest. Only results for Category 1 (molecular formula identification) were submitted. The SIRIUS method and the parameters used are briefly described, followed by detailed analysis of the results and a discussion of cases where SIRIUS2 was unable to come up with the correct molecular ...
Kai Dührkop   +2 more
openaire   +3 more sources

Metabolomics Changes of Serum and Tissues in Mice Died of Acute Tetracaine Poisoning [PDF]

open access: yesFayixue Zazhi, 2021
Objective To study the changes of metabolites in serum and tissues (kidney, liver and heart) of mice died of acute tetracaine poisoning by metabolomics, to search for potential biomarkers and related metabolic pathways, and to provide new ideas for the ...
LIU Wen-qiao, BAI Rui, MA Chun-ling, et al.
doaj   +1 more source

From mass to structure: An aromaticity index for high-resolution mass data of natural organic matter [PDF]

open access: yes, 2006
Recent progress in Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS) provided extensive molecular mass data for complex natural organic matter (NOM). Structural information can be deduced solely from the molecular masses for ions with
Benecke   +16 more
core   +1 more source

Control effects of metabolites of endophytic fungus Alternaria sp. GHX-P17 on bacterial wilt and changes of protective enzymes in Pogostemon cablin

open access: yesGuangxi Zhiwu, 2023
There is a long history to cultivate the Pogostemon cablin in Guangdong Province, and it is a famous medicinal material. The bacterial wilt is the important disease that impacts the production and quality of P. cablin.
Xiaoqing CHENG   +4 more
doaj   +1 more source

Berberine Facilitates Extinction of Drug-Associated Behavior and Inhibits Reinstatement of Drug Seeking

open access: yesFrontiers in Pharmacology, 2020
A high rate of relapse is a major clinical problem among drug-addicted individuals. Persistent traces of drug-associated reward memories contribute to intense craving and often trigger relapse.
Xi Shen   +10 more
doaj   +1 more source

A Systematic Approach to Identifying Protein-Ligand Binding Profiles on a Proteome Scale [PDF]

open access: yes, 2008
Identification of protein-ligand interaction networks on a proteome scale is crucial to address a wide range of biological problems such as correlating molecular functions to physiological processes and designing safe and efficient therapeutics.
Lei Xie   +3 more
core   +2 more sources

Determination of barbiturates in hair samples by using a validated UHPLC-HRMS method: application in investigation of drug-facilitated sexual assault

open access: yesForensic Sciences Research, 2019
In recent years, benzodiazepines and benzodiazepine-like drugs are the most common substances associated with drug-facilitated sexual assaults (DFSA); however, barbiturates are also detected occasionally.
Di Wen   +8 more
doaj   +1 more source

Endoplasmic Reticulum Stress Is Associated with the Mesencephalic Dopaminergic Neuron Injury in Stressed Rats

open access: yesAnalytical Cellular Pathology, 2021
An increasing number of people are in a state of stress due to social and psychological pressures, which may result in mental disorders. Previous studies indicated that mesencephalic dopaminergic neurons are associated with not only reward-related ...
Shiba Niu   +7 more
doaj   +1 more source

Comparative Analysis of Molecular Clouds in M31, M33 and the Milky Way [PDF]

open access: yes, 2007
We present BIMA observations of a 2$\arcmin$ field in the northeastern spiral arm of M31. In this region we find six giant molecular clouds that have a mean diameter of 57$\pm$13 pc, a mean velocity width of 6.5$\pm$1.2 \kms, and a mean molecular mass of
Christine D. Wilson   +7 more
core   +2 more sources

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