An overview of Monascus fermentation processes for monacolin K production
Open Chemistry, 2020 In Asia, Monascus has been used in food fermentation for nearly a thousand years. It has attracted increasing attention in recent years due to its ability to produce a variety of important active substances such as monacolin K (MK) and pigments. MK is an
Yafeng Zheng, Zhiwei Huang
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Chemical Physics Impact, 2023 To identify a novel inhibitor of 3‑hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the current perspective has shifted toward a B12N12 nanocage that also has cardioprotective properties.
Vahid Khori +5 more
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Monacolin and atorvastatin in cardiovascular prevention – an attempt at positioning [PDF]
Pediatria i Medycyna Rodzinna, 2017 Cardiovascular diseases are the leading cause of premature death worldwide. Dyslipidemia, in turn, is the most common modifiable cardiovascular risk factor. According to NATPOL 2011, hypercholesterolaemia defined as total cholesterol of at least 190 mg/
Marcin Barylski
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Scientific Opinion on the substantiation of a health claim related to monacolin K in SYLVAN BIO red yeast rice and maintenance of normal blood LDL-cholesterol concentrations pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
EFSA Journal, 2013 Following an application from Sylvan Bio Europe BV, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the Netherlands, the Panel on Dietetic Products, Nutrition and ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
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Optimization of fermentation conditions for acidic Monacolin K production by Monascus purpureus with response surface method [PDF]
Zhongguo niangzaoAcidic Monacolin K is a physiologically active substance with multiple functions such as lipid-lowering, anti-fatigue, anti-microbial, anti-tumor and neuroprotective, and is considered to be a good hypolipidemic drug.
CHEN Yang, HONG Housheng
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Monacolin K in the treatment of hypercholesterolemia - chance or threat? [PDF]
Journal of Education, Health and SportIntroduction Hypercholesterolemia is a primary element leading to the occurrence of cardiovascular diseases, which are the most common cause of death worldwide. One of the most effective drugs used in the treatment of hypercholesterolemia are statins.
Katarzyna Krotowska
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Effects of Monacolin K in Nondiabetic Patients with NAFLD: A Pilot Study. [PDF]
Nutrients, 2023 Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver condition with significant risk of progression to steatohepatitis and cirrhosis. Therapeutic strategies in NAFLD include lifestyle changes mainly related to dietary interventions and use
Da Porto A +10 more
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Biological Research, 2011 In China, Monascus spp., a traditional fungus used in fermentation, is used as a natural food additive. Monascus spp. can produce a secondary metabolite, monacolin K namely, which is proven to be a cholesterol-lowering and hypotensive agent.
Jia-Long Sun +3 more
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NaCl Inhibits Citrinin and Stimulates Monascus Pigments and Monacolin K Production [PDF]
Toxins, 2019 Applications of beneficial secondary metabolites produced by Monascus purpureus (M. purpureus) could be greatly limited for citrinin, a kidney toxin. The link of NaCl with cell growth and secondary metabolites in M.
Zhixin Zhen +6 more
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Utilization of soybean residue to produce monacolin K -cholesterol lowering agent [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2009 Soybean residue is a byproduct from the manufacture of soybean milk and tofu which are popular foods in Thailand. Soybean residue was used as substrate in solid state fermentation by Monascus purpureus IFRPD 4046 to produce monacolin K, a cholesterol ...
Jantima Japakaset1, Chakamas Wongkhalaung1 and Vichien Leelawatcharamas2 +2 more
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