Results 21 to 30 of about 3,104 (182)

An overview of Monascus fermentation processes for monacolin K production

Open Chemistry, 2020
In Asia, Monascus has been used in food fermentation for nearly a thousand years. It has attracted increasing attention in recent years due to its ability to produce a variety of important active substances such as monacolin K (MK) and pigments. MK is an
Wen Qinyou, Cao Xiaohua, Chen Zhiting, Xiong Zixiao, Liu Jianghong, Cheng Zuxin, Zheng Zhenghuai, Long Chuannan, Zheng Baodong, Huang Zhiwei   +9 more
doaj   +3 more sources

NaCl Inhibits Citrinin and Stimulates Monascus Pigments and Monacolin K Production [PDF]

Toxins, 2019
Applications of beneficial secondary metabolites produced by Monascus purpureus (M. purpureus) could be greatly limited for citrinin, a kidney toxin. The link of NaCl with cell growth and secondary metabolites in M.
Zhixin Zhen, Xiaoqian Xiong, Yingbao Liu, Jialan Zhang, Shaojin Wang, Li Li, Mengxiang Gao   +6 more
doaj   +5 more sources

Identification of the high-yield monacolin K strain from Monascus spp. and its submerged fermentation using different medicinal plants [PDF]

Botanical Studies, 2022
Background Medical plants confer various benefits to human health and their bioconversion through microbial fermentation can increase efficacy, reduce toxicity, conserve resources and produce new chemical components.
Yu-Pei Chen, Hong-Tan Wu, Ing-Er Hwang, Fang-Fang Chen, Jeng-Yuan Yao, Yiling Yin, Meng-Yun Chen, Li-Ling Liaw, Yang-Cheng Kuo   +8 more
doaj   +2 more sources

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]

J Basic Microbiol
ABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Yang C, Yajing Y, Housheng H.
europepmc   +2 more sources

Impact of Monacolin K‐Containing Supplements on Lipid Profile: A Meta‐Analysis of Randomised Controlled Trials [PDF]

Endocrinology, Diabetes & Metabolism
Background Natural products have gained attention as alternative strategies for managing dyslipidemia, particularly in individuals who are resistant or unwilling to use conventional pharmacotherapies. Monacolin K, a compound derived from natural sources,
Tannaz Jamialahmadi, Elaheh Mirhadi, Sercan Karav, Prashant Kesharwani, Amirhossein Sahebkar   +4 more
doaj   +2 more sources

Repurposing of monacolin K decorated BN nanoparticle on inhibition of HMG-CoA reductase: In silico approach

Chemical Physics Impact, 2023
To identify a novel inhibitor of 3‑hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the current perspective has shifted toward a B12N12 nanocage that also has cardioprotective properties.
Vahid Khori, Mahdi Zahedi, Hassan Mirzaei, Ali Jabbari, seyedbabak Mojaveraghili, Seyed Ghadir Hosseini   +5 more
doaj   +2 more sources

Scientific Opinion on the substantiation of a health claim related to monacolin K in SYLVAN BIO red yeast rice and maintenance of normal blood LDL-cholesterol concentrations pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2013
Following an application from Sylvan Bio Europe BV, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the Netherlands, the Panel on Dietetic Products, Nutrition and ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +3 more sources

Monacolin and atorvastatin in cardiovascular prevention – an attempt at positioning

Pediatria i Medycyna Rodzinna, 2017
Cardiovascular diseases are the leading cause of premature death worldwide. Dyslipidemia, in turn, is the most common modifiable cardiovascular risk factor. According to NATPOL 2011, hypercholesterolaemia defined as total cholesterol of at least 190 mg/
Marcin Barylski
doaj   +2 more sources

Determination of Monacolin K and Citrinin in the Presence of Other Active Ingredients Found in Selected Food Supplements by HPLC-DAD [PDF]

Molecules
A universal HPLC method with diode array detection was developed for the separation and determination of the lactone and acid forms of monacolin K in the presence of other active ingredients (vitamins B1, B6, B12, and folic acid) found in selected ...
Urszula Hubicka, Barbara Żuromska-Witek, Marek Szlósarczyk, Ewelina Sołtys, Martyna Rusak, Izabela Gacal   +5 more
doaj   +2 more sources

Effect of γ-Heptalactone on the Morphology and Production of Monascus Pigments and Monacolin K in Monascus purpureus. [PDF]

J Fungi (Basel), 2022
Monascus is used widely in Asian countries and produces various biologically active metabolites, such as Monascus pigments (MPs) and monacolin K (MK). In this study, the effect of γ-heptalactone on secondary metabolites and mycelial growth during Monascus purpureus M1 fermentation was investigated. After the addition of 50 μM γ-heptalactone, the yields
Shi R, Luo Q, Liu Y, Chen W, Wang C.
europepmc   +5 more sources