Chemical Profiling and In Vitro Cytotoxicity Assessment of Commercial Red Yeast Rice Ingredients [PDF]
FoodsRed yeast rice (RYR) food supplements are widely used for cholesterol management due to their monacolin content, particularly monacolin K (MK), which shares the same chemical structure as lovastatin, a compound associated with several side effects.
Paola Nezi +8 more
doaj +2 more sources
Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial. [PDF]
Nutrients, 2023 Certain nutraceuticals, mainly containing red yeast rice, might be considered as an alternative therapy to statins in patients with dyslipidemia, although there is still insufficient evidence available with respect to long-term safety and effectiveness ...
Angelopoulos N +5 more
europepmc +2 more sources
Optimization of red yeast rice fermentation for enhanced Monacolin K accumulation and assessment of α-amylase inhibitory activity for antihyperglycemic potential [PDF]
Ho Chi Minh City Open University Journal of Science - Engineering and TechnologyMonascus sp. can break down starch-based substrates into bioactive metabolites with antibacterial, anticancer, antidiabetic, and anti-obesity effects.
Nu Dieu Hong Dao +3 more
doaj +3 more sources
Effects of Arginine and Other Substances on Synthesis of Monacolin K and Monascus Pigment of Monascus purpureus(精氨酸等物质对紫色红曲菌产Monacolin K及红曲色素的影响) [PDF]
Shipin kexue jishu xuebao, 2021 Based on the preliminary results of the untargeted metabonomics in Monascus purpureus, differential metabolites such as arginine, L-malic acid, D-glucose, niacinamide, α-oxoglutaric acid, phenylalanine, lysine, thiamine pyrophosphate,flavin ...
ZHU Qianqian(朱倩倩) +7 more
doaj +1 more source
Effects of Nicotinamide on Growth and Secondary Metabolite Synthesis of Monascus purpureus(烟酰胺对紫色红曲菌生长和次级代谢产物合成的影响) [PDF]
Shipin kexue jishu xuebao, 2021 Monascus purpureus M1 with stable yield of Monacolin K preserved in the Beijing Engineering and Technology Research Center of Food Additive, was used as the starting strain, the effects of nicotinamide addition on the secondary metabolites of Monascus ...
ZHANG Han(张函) +6 more
doaj +1 more source
Glutamic acid promotes monacolin K production and monacolin K biosynthetic gene cluster expression in Monascus. [PDF]
AMB Express, 2017 This study investigated the effects of glutamic acid on production of monacolin K and expression of the monacolin K biosynthetic gene cluster. When Monascus M1 was grown in glutamic medium instead of in the original medium, monacolin K production ...
Zhang C +6 more
europepmc +2 more sources
Research Progress of Monacolin K Synthesis in Monascus(红曲霉合成莫纳克林K的研究进展) [PDF]
Shipin kexue jishu xuebao, 2023 i>Monascus is a kind of medicinal and edible filamentous fungus, which is widely used in food, medicine, biocatalysis and other fields. Monacolin K is the main metabolic functional active product of Monascus, with biological activities such as lipid ...
ZHANG Chan(张婵) +7 more
doaj +1 more source
Journal of Pure and Applied Microbiology, 2023 This study aims to reconcile industrially suitable strains of higher red pigment producing Monascus purpureus MPA5 and higher Monacolin K producing Monascus ruber MRA7, were tried to fuse for development of increased efficacy of targeted secondary ...
Anindita Sinha, Keka Sarkar
doaj +1 more source
Czech Journal of Food Sciences, 2019 Inorganic salts are important factors in the growth and secondary metabolites production of microorganisms. This study investigated the influences of divalent metal cations, Mn2+, Zn2+, and Mg2+ on the cell growth and Monacolin K production in Monascus ...
Lin Lin +4 more
doaj +1 more source
Effect of Four Kind of Medium on Monascus M1 with Monacolin K Production and Real-time Quantitative Analysis(4种培养基对红曲霉M1莫纳可林K产量影响及基因差异表达分析) [PDF]
Shipin kexue jishu xuebao, 2016 Monacolin K is one of the important secondary metabolites of Monascus sp. The influence of Monacolin K production for Monascus M1 on four kinds of fermentation substrate were studied.And the mRNA expression of Monacolin K biosynthesis gene cluster was ...
LIN Lin(林琳) +5 more
doaj +1 more source