Results 61 to 70 of about 3,104 (182)
Journal of Future Foods, 2023 Hypercholesterolemia is a risk factor of cardiovascular diseases, which have been managed using statin drugs. Red yeast rice (RYR) as a traditional food in the Eastern Asia countries has anti-hyperlipidemia activity.
Gong Chen +5 more
doaj +1 more source
Production of the secondary metabolites γ-aminobutyric acid and monacolin K by Monascus [PDF]
Journal of Industrial Microbiology & Biotechnology, 2003 gamma-Aminobutyric acid (GABA), a hypotensive agent, and monacolin K, a cholesterol-lowering drug, can be produced by Monascus spp. Under optimal culture conditions, the products of fermentation using Monascus spp. may serve as a multi-functional dietary supplement and can prevent heart disease.
Yuan-Chi, Su +3 more
openaire +2 more sources
Foods, 2017 Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for a long time in Asian cuisine and traditional medicine.
Thu Nguyen +2 more
doaj +1 more source
Effects of Glycerol on Monascus CG-6 Monacolin K Synthesis and Related Gene Expression(甘油对红曲霉CG-6莫纳可林K合成及相关基因表达的影响) [PDF]
Shipin kexue jishu xuebao, 2018 In this paper, effects of glycerol on the synthesis and related genes expression of Monascus CG-6 Monacolin K were studied. The yields of Monacolin K and related genes expression were determined by high performance liquid chromatography and real-time PCR.
XUE Yibin(薛意斌) +7 more
doaj +1 more source
Optimization of Monacolin K Production by Monascus purpureus MTTC 410 in Submerged Fermentation
, 2012 Monascus purpureus, a traditional Chinese fermentation fungus, is used as a natural dietary supplement. Among the metabolites of M. purpureus, monacolin K (lovastatin) is found to be very important and have been proven to be cholesterol-lowering drug ...
Mohan, A. Dhale +2 more
core +1 more source
Food Safety and Health, Volume 4, Issue 1, Page 138-146, January 2026.A graphical abstract showing lovastatin extraction from Monascus purpureus fermented finger millet. ABSTRACT Red yeast rice (RYR), a traditional fermented food product derived from Monascus purpureus cultivation on rice, has been utilized as both food and food additive throughout East Asian countries for centuries.
Monu Kumar +2 more
wiley +1 more source
, 2020 A positive prognosis of triple-negative breast cancer can be considered as one of the major challenges in clinical studies; accordingly, scientific research has the mission to find out novel chemotherapeutics to make it curable.
Riccio R. +3 more
core +1 more source
Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies
ChemBioChem, Volume 26, Issue 21, November 8, 2025.The yield and turnover of in vitro natural product biosynthesis, and even its feasibility, are determined by intermolecular interactions. Reaction engineering allows to improve the performance of such complex biocatalytic systems. Natural products are widely used as pharmaceuticals and agrochemicals, or as active ingredients in food and cosmetics ...
Elsa Sánchez‐García +2 more
wiley +1 more source
Monacolin K affects lipid metabolism through SIRT1/AMPK pathway in HepG2 cells
, 2014 Monacolin K is the secondary metabolite isolated from Monascus spp. It is the natural form of lovastatin, which is clinically used to reduce the synthesis of cholesterol by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase. In the present study,
Wang, Shyang-Guang +5 more
core +1 more source
Molecular Nutrition &Food Research, Volume 69, Issue 21, November 2025.This retrospective study evaluated the effects of nutraceutical supplementation (NS) and a Mediterranean hypocaloric diet (MHD) in NAFLD patients. Forty‐five overweight/obese subjects followed MHD with or without NS. After 3 months, only the MHD + NS group showed significant improvements in liver steatosis indices and inflammation.
Mariana Di Lorenzo +11 more
wiley +1 more source