Results 51 to 60 of about 9,020,555 (147)

Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies

ChemBioChem, Volume 26, Issue 21, November 8, 2025.
The yield and turnover of in vitro natural product biosynthesis, and even its feasibility, are determined by intermolecular interactions. Reaction engineering allows to improve the performance of such complex biocatalytic systems. Natural products are widely used as pharmaceuticals and agrochemicals, or as active ingredients in food and cosmetics ...
Elsa Sánchez‐García, Stephan Lütz, Markus Nett   +2 more
wiley   +1 more source

Overexpression of Monacolin K Biosynthesis Genes in the Monascus purpureus Azaphilone Polyketide Pathway

, 2019
Monascus purpureus is an important food and drug microbial resource through the production of a variety of secondary metabolites, including monacolin K, a well-recognized cholesterol-lowering agent.
Shuai Hao (3367121), Han Zhang (110653), Chan Zhang (752696), Qianqian Zhu (48100), Baoguo Sun (1639966), Jian Liang (79113), Anan Zhang (6384251), Chengtao Wang (2835524)   +7 more
core   +1 more source

Antioxidant properties and production of monacolin k, citrinin, and red pigments during solid state fermentation of purple rice (Oryzae sativa) varieties by Monascus purpureus

Czech Journal of Food Sciences, 2017
This study aims to evaluate the effects of various purple rice varieties on the production of monacolin K, citrinin, and red pigments by Monascus purpureus CMU002U (UV-mutant strain) and their antioxidant properties.
Prodpran Pengnoi, Rapeepun Mahawan, Chartchai Khanongnuch, Saisamorn Lumyong   +3 more
doaj   +1 more source

An overview on the therapeutic potential and anticancer mechanism of Monacolin K / Lovastatin

Pharmacological Research - Modern Chinese Medicine, 2022
Rising pollution levels, altered lifestyles, and poor diets are contributing to a dramatic increase in the prevalence of cancer worldwide. When it comes to threats to human health, cancer is among the top concerns.
Monu Monu, Krishan D Sehrawat, Anoop Singh, Gaurav Chaudhary, Deepak Bamal, Anita R Sehrawat   +5 more
doaj   +1 more source

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

Molecular Nutrition &Food Research, Volume 69, Issue 21, November 2025.
This retrospective study evaluated the effects of nutraceutical supplementation (NS) and a Mediterranean hypocaloric diet (MHD) in NAFLD patients. Forty‐five overweight/obese subjects followed MHD with or without NS. After 3 months, only the MHD + NS group showed significant improvements in liver steatosis indices and inflammation.
Mariana Di Lorenzo, Luca Pipicelli, Laura Aurino, Concetta Sozio, Anna Palmiero, Domenico Palmieri, Marta Lombardi, Bruna Guida, Mariarosaria Santillo, Maria Serena Lonardo, Giuliana La Rosa, Simona Damiano   +11 more
wiley   +1 more source

Red Yeast Rice as a natural source of Monacolin K – the efficacy among patients with dyslipidemia. A literature review

Journal of Education, Health and Sport
Background: Dyslipidemia is a common disease worldwide associated with increased cardiovascular risk. It is associated with many possible health consequences. An important issue in the treatment of dyslipidemia is lifestyle modification.
Aleksandra Simlat, Aleksandra Sado, Bartłomiej Lisik, Filip Skowierzak, Klaudia Kozyra, Sylwia Kozieł-Kwit, Wiktoria Rogowska, Krzysztof Szada-Borzyszkowski, Mariusz Wręczycki, Kacper Sawczuk   +9 more
doaj   +1 more source

The Production of Nata Colored by Monascus purpureus J1 Pigments as Functional Food

Microbiology Indonesia, 2010
Pigments from Monascus sp. may color nata. The mold also produces monacolin K that inhibits HMG-CoA reductase affecting the reduction of blood cholesterol. The aim of this study was to produce the colored nata containing monacolin K.
TRESNAWATI PURWADARIA, LISRINA GUNAWAN, AGUSTIN WYDIA GUNAWAN   +2 more
doaj   +1 more source

Optimization of Mixed Fermentation Conditions of Oat Bran and Red Yeast Rice Powder

Liang you shipin ke-ji, 2021
Oat bran was used as a substrate, and red yeast rice powder was added to provide fermented bacteria for mixed fermentation.The effective lipid-lowering ingredients in the mixture were used as evaluation index, and the fermentation process conditions ...
GAO Yu-qi, ZHANG Xiu-jin, LI Zai-gui
doaj   +1 more source

Revisiting Cholesterol‐Lowering Nutraceuticals and Functional Foods: Mechanistic Insights Into Cholesterol Homeostasis and Gut Microbiota

Food Chemistry International, Volume 1, Issue 3, Page 265-293, September 2025.
Mechanistic Insights into Cholesterol Homeostasis and Gut Microbiota. ABSTRACT The gut microbiota acts as a crucial intermediary between diets and human health. The accumulating evidence suggests that gut microbiota may play a significant role in cholesterol metabolism.
Xiaoxuan Zhang, Huafang Ding, Wensen He, Shouhe Huang, Lin Lei   +4 more
wiley   +1 more source

Screening of Azaphilone Derivatives From -Fermented Rice (Red Yeast Rice) and Their Evaluation as Nonsteroidal Androgen Receptor Antagonists

Natural Product Communications, 2019
Monascus pilosus BCRC 38093 is a mutant strain of M. pilosus BCRC 38072. The 95% ethanol extract of red yeast rice fermented by M. pilosus BCRC 38093 showed 4 major signals on high performance liquid chromatography (HPLC) examination.
Ming-Der Wu, Ming-Jen Cheng, Yen-Lin Chen, Tai-Wei D. Liu, Kai-Ping Chen   +4 more
doaj   +1 more source