Results 91 to 100 of about 25,416 (201)

Nurses' Pain Assessment and Attitudes: A Qualitative Study in a Neurointensive Care Unit

Nursing in Critical Care, Volume 31, Issue 2, March 2026.
ABSTRACT Background As analgo‐sedation gains prominence, a significant portion of adult ICU patients—including those in neurointensive care units (neuro‐ICUs)—remain awake and conscious throughout their stay. Despite this, neuro‐ICU patients frequently experience moderate to severe pain, highlighting the critical need for enhanced pain assessment.
Janni Kristina Voldbjerg, Suzanne Forsyth Herling, Birgitte Nørgaard   +2 more
wiley   +1 more source

The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats

Frontiers in Pharmacology
The ability of morphine to decrease cysteine transport into neurons by inhibition of excitatory amino acid transporter 3 (EAA3) may be a key molecular mechanism underlying the acquisition of physical and psychological dependence to morphine.
Paulina M. Getsy, Gregory A. Coffee, James N. Bates, Theodore Parran, Lee Hoffer, Santhosh M. Baby, Peter M. MacFarlane, Zackery T. Knauss, Derek S. Damron, Yee-Hsee Hsieh, Jason A. Bubier, Devin Mueller, Stephen J. Lewis, Stephen J. Lewis, Stephen J. Lewis   +14 more
doaj   +1 more source

Evaluation of the Enhanced Recovery After Surgery (ERAS) Guidance for Patients With Spinal Metastasis

Orthopaedic Surgery, Volume 18, Issue 3, Page 385-401, March 2026.
The flow diagram of study. ABSTRACT Surgery continues to remain the most effective treatment for spinal metastasis (SM). As the number of surgeries continues to grow, the need for consensus guidelines for optimal perioperative care is imperative. Enhanced recovery after surgery (ERAS) protocols were created for this purpose. The objective of this study
Fanjie Li, Wenlong Yu, Changchang Shen, Jinxin Luo, Zhibin Li, Qiang Gao, Chengchun Jin, Tao Li, Quan Huang, Shuqiang Wang, Peilin Chu, Mengchen Yin   +11 more
wiley   +1 more source

Mitigating morphine dependence and withdrawal: The role of venlafaxine and calcium channel blockers in mitochondrial damage and oxidative stress in the brain

Brain Research Bulletin
Background: The reasons for morphine dependence and withdrawal symptoms are oxidative stress and dysfunction of cell mitochondria in the brain. Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), mitigates oxidative stress, while calcium ...
Radman Amiri, Faezeh Fallah, Behnam Ghorbanzadeh, Ali Akbar Oroojan, Mohammad Amin Behmanesh, Soheila Alboghobeish   +5 more
doaj   +1 more source

Caring in Ambulance Encounters With Older Patients With Complex Care Needs: A Phenomenographic Study

Scandinavian Journal of Caring Sciences, Volume 40, Issue 1, March 2026.
ABSTRACT Background Although caring is a core concept in nursing, its meaning is not uniform, and perceptions may vary across care settings. In ambulance care, encounters with older patients with complex care needs present challenges that may shape how caring is understood and practiced. Guided by a lifeworld‐led caring perspective, this study explores
Ann‐Therese Hedqvist, Mats Holmberg
wiley   +1 more source

Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice. [PDF]

iScience, 2023
Zhang J, Lu Y, Jia M, Bai Y, Sun L, Dong Z, Tian W, Yin F, Wei S, Wang Y.   +9 more
europepmc   +1 more source

Loss of Astrocytic µ Opioid Receptors Exacerbates Aversion Associated with Morphine Withdrawal in Mice: Role of Mitochondrial Respiration. [PDF]

Cells, 2023
Murlanova K, Jouroukhin Y, Novototskaya-Vlasova K, Huseynov S, Pletnikova O, Morales MJ, Guan Y, Kamiya A, Bergles DE, Dietz DM, Pletnikov MV.   +10 more
europepmc   +1 more source

Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice. [PDF]

Behav Brain Res, 2023
Bedard ML, Lord JS, Perez PJ, Bravo IM, Teklezghi AT, Tarantino LM, Diering GH, McElligott ZA.   +7 more
europepmc   +1 more source

Effect of Hydro-alcoholic extract of Jasminum sambac on morphine withdrawal symptoms in rats

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: The exact mechanisms of morphine dependence and withdrawal syndrome remain unclear. Many studies have been performed to find agents with low dependency in order to decrease withdrawal symptoms. On the other hand studies have shown the
Mohammad Raman Moloudi, Hila Moqbel, Dara Dastan, Katayoon Hasanzadeh, Bijan Noori, Esmael Izadpanah   +5 more
doaj  

Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice. [PDF]

Nat Commun, 2023
Sheng H, Lei C, Yuan Y, Fu Y, Cui D, Yang L, Shao D, Cao Z, Yang H, Guo X, Chu C, Wen Y, Cai Z, Chen M, Lai B, Zheng P.   +15 more
europepmc   +1 more source