Results 21 to 30 of about 26,051 (190)
Effects of aging on morphine withdrawal in the rat
Experimental Gerontology, 1994 Little is known about the effects of aging on the process of opiate dependence and withdrawal in the rat. The present study was undertaken to quantitate naloxone-precipitated opiate withdrawal in young (3-4 months old) and aged (24 month old) Long-Evan female rats.
Department of Pharmacodynamics and The Center for the Neurobiology of Aging, University of Florida, Gainesville, Florida 32610, USA ( host institution ) +1 more
openaire +3 more sources
Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain
Advanced Science, EarlyView.Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh +7 more
wiley +1 more source
The Effects of Hydroalcoholic Extract of Satureja khuzestanica on Naloxone-Induced Morphine Withdrawal Symptoms in Wistar Rats [PDF]
International Journal of Basic Science in Medicine, 2020 Introduction: The inflammatory system, oxidative stress, and cholinergic pathways are some important factors in long-term opioid dependence withdrawal.
Bahareh Ebrahimi, Saeed Esmaeili-Mahani
doaj +1 more source
Veterinary Record, EarlyView.Abstract Background Managing open wounds in birds is challenging. This study compared leukocyte‐ and thrombocyte‐rich fibrin (L‐TRF) and autologous grafts for treating wounds in the tarsometatarsus of chickens. Methods Full‐thickness wounds were experimentally induced in the tarsometatarsus of 23 healthy adult chickens.
Vivian Ferreira Rech +6 more
wiley +1 more source
Differential Changes in Expression of Stress- and Metabolic-Related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal. [PDF]
PLoS ONE, 2013 Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Bernadett Pintér-Kübler +6 more
doaj +1 more source
Addiction, EarlyView.Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson +13 more
wiley +1 more source
The Effect of Resistance Training on Some Markers of Apoptosis Caused by Diabetic Cardiomyopathy and Morphine withdrawal Syndrome in Diabetic Male Rats [PDF]
مجله دانشگاه علوم پزشکی جیرفت, 2023 Introduction: Morphine withdrawal syndrome is one of the aggravating factors of apoptosis in diabetic cardiomyopathy. The purpose of this research was to investigate the effect of resistance training on some markers of apoptosis caused by diabetic ...
Maryam Sadegh Joola +2 more
doaj
Addiction, EarlyView.Abstract Aims To examine the comparative effects of slow‐release oral morphine (SROM) vs. methadone for the treatment of opioid use disorder (OUD) on healthcare use. Design This retrospective cohort study emulated a target trial using electronic medical record data from Vancouver Coastal Health Authority linked with population‐based administrative ...
Vivienne Y. Zhou +5 more
wiley +1 more source
Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.
PLoS ONE, 2011 A major obstacle in treating drug addiction is the severity of opiate withdrawal syndrome, which can lead to unwanted relapse. Mitragynine is the major alkaloid compound found in leaves of Mitragyna speciosa, a plant widely used by opiate addicts to ...
Beng-Siang Khor +3 more
doaj +1 more source
The American Journal on Addictions, EarlyView.Abstract Background and Objectives Readmission to residential treatment increases healthcare costs, strains publicly funded systems, and may not adequately meet clients' needs. This study examined rates and predictors of readmission to residential treatment among clients transitioned from detoxification services.
Abreham Mekonnen
wiley +1 more source