Results 31 to 40 of about 55,011 (233)

The effect of an incremental resistance training program on some apoptotic markers in the heart tissue of rats with morphine withdrawal syndrome [PDF]

مجله علوم پزشکی فیض (پیوسته), 2023
Background and Aim: The use of different drugs in withdrawal syndrome usually has little effectiveness and causes the person to become dependent on new substances.
Maryam Sadegh joola, Abas Saremi, Mojtaba Khansooz   +2 more
doaj   +2 more sources

Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]

, 1998
The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Biersack, H. J., Broich, K., Danos, P., Grunwald, F., Hoflich, G., Kasper, S., Klemm, E., Krappel, C., Möller, Hans-Jürgen, Overbeck, B.   +9 more
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Maternal methadone use in pregnancy : factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources [PDF]

, 2009
The objectives of this study were to investigate factors associated with the development of neonatal abstinence syndrome (NAS) and to assess the implications for healthcare resources of infants born to drug-misusing women. Design.
Dryden, C., Hepburn, M., Mactier, H., Young, D.   +3 more
core   +1 more source

Flavonoids Reduce Morphine Withdrawal In-vitro

Journal of Pharmacy and Pharmacology, 1998
AbstractThe effects of quercetin, flavone, catechin and chrysin on the naloxone-precipitated withdrawal contracture of the acute morphine-dependent guinea-pig ileum have been investigated in-vitro.After 4 min in-vitro exposure to morphine a strong contracture of guinea-pig isolated ileum was observed after the addition of naloxone.
CAPASSO, Anna, PIACENTE, Sonia, PIZZA, Cosimo, SORRENTINO L.   +3 more
openaire   +3 more sources

The (–)-Borneol Effect on Addiction/Abstinence by Morphine in Mice

Drugs and Drug Candidates, 2023
Opioids such as morphine are the first choice in acute and chronic pain treatment. However, they lead to addiction. Several studies have searched (i) to find a molecule that can replace morphine use or (ii) to reduce its adverse effects.
Maurício Pires de Moura do Amaral, Melquisedeque da Rocha Viana, Altamiro Teixeira Osório, Luciano da Silva Lopes, Fabrício Pires de Moura do Amaral, Massimo Lucarini, Alessandra Durazzo, Daniel Dias Rufino Arcanjo, Rita de Cássia Meneses Oliveira   +8 more
doaj   +1 more source

Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. [PDF]

, 2020
Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the ...
Carrette, Lieselot LG, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Kononoff, Jenni, Palmer, Abraham A, Schweitzer, Paul, Solberg Woods, Leah C   +7 more
core  

Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice [PDF]

, 2014
Aim: To investigate the effects of ATPM-ET [(−)-3-N-Ethylaminothiazolo [5,4-b]-N-cyclopropylmethylmorphinan hydrochloride] on physical dependence and behavioral sensitization to morphine in mice.
Chen, Jie, Cheng, Yun, Chi, Zhi-qiang, Li, Fu-ying, Liu, Jing-gen, Lu, Gang, Neumeyer, John L, Sun, Jian-feng, Tao, Yi-min, Wang, Yu-hua, Xu, Xue-jun, Zhang, Ao   +11 more
core   +1 more source

Effects of glucosamine against morphine-induced antinociceptive tolerance and dependence in mice

Journal of Biomedical Science, 2019
Background The most important limitations of morphine in pain therapy are its tolerance and dependence. In this study, we evaluated the protective effect of glucosamine against morphine-induced tolerance and dependence in mice.
Faezeh Basiri, Abolfazl Rad, Davood Mahdian, Mehdi Molavi, Bahareh Amin   +4 more
doaj   +1 more source

Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]

, 1991
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
core  

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]

, 2015
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli, A Cippitelli, A Cippitelli, A Ettenberg, A Ettenberg, A Plaza-Zabala, A Sekino, A Van't Veer, AC Hansson, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AE Higley, AM Chirila, AM Polter, AM Thierry, AN Carey, Anh D Lê, AS Kreibich, AY Deutch, B Boutrel, B Lee, B Ribeiro Do Couto, B Setlow, B Wang, B Wang, B Wang, B Wang, B Wang, BB Land, BH Westerink, BL Lewis, BM Cox, BR Lee, C Cifani, C Li, CD Schmoutz, CJ Sanchez, CJ Sanchez, CK Nielsen, CL Pickens, CP Ford, CP O'Brien, CR Gerfen, D Economidou, D Epstein, D Funk, D Funk, D Highfield, D Highfield, D Highfield, D Liu, D Rodaros, D Rotllant, David A Baker, DC Glass, DEJ Redmond, DH Epstein, DJ Calu, DJ Calu, DM Buffalari, DM Buffalari, DM Buffalari, Douglas Funk, DR Gehlert, DR Staub, DS Zahm, DT George, DW Schulz, DW Self, E Krupitsky, EA Stone, EB Margolis, EJ Khantzian, EN Graf, EN Graf, EP Zorrilla, EP Zorrilla, F Chaouloff, F Cohen, F Georges, F Leri, F Sedki, F Weiss, FC Cruz, FJ White, G Aston-Jones, G de Guglielmo, G Zislis, GF Koob, GP Chrousos, GR Valdez, H Selye, H Yamada, HC Fox, HC Fox, J Jenkins, J Stewart, J Wang, JA Deutch, JA Gray, JA Simms, JC Umhau, JD Bremner, JD Bremner, JD Shepard, JE LeDoux, JE Morley, JJ Anker, JJ Anker, JK Richards, JK Seamans, JL McGaugh, JM Blacktop, JM Bossert, JM Bossert, JM Bossert, JM Fritschy, JN Cleck, John R Mantsch, JP McLaughlin, JP Schroeder, JR Glowa, JR Mantsch, JR Mantsch, JR Mantsch, JR Mantsch, JR McReynolds, JR Schank, JR Schank, JR Schank, JV Aldrich, JV Aldrich, K McFarland, K Van Pett, KJ Jackson, KL Conrad, KL Shelton, L Lu, L Lu, L Lu, L Lu, L Zhou, LA Briand, LE Kwako, LG Kirby, LK Vaughn, M Davis, M Davis, M Heilig, M Sakanaka, MA Ungless, MB Bannon, MD Cassell, ME Bouton, ME Bouton, ME Carroll, MEP Seligman, MF Dallman, MK Greenwald, ML Jobes, ML Price, MM Moran-Santa Maria, MM Moran-Santa Maria, MR Bruchas, MR Bruchas, MT Stefanik, MW Feltenstein, MW Feltenstein, MW Hale, N Capriles, N Omelchenko, N Sidhpura, NA Chen, NM Graziane, O Vranjkovic, O Vranjkovic, P Enrico, PE Sawchenko, PJ Fletcher, PM Beardsley, PM Beardsley, PS Regier, PV Piazza, PW Kalivas, PW Kalivas, PW Kalivas, PW Marinelli, R Ciccocioppo, R Haynes, R Kvetnansky, R Martin-Fardon, R Mongeau, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Takahata, RC Pierce, RC Twining, RD Weiss, RE See, RE See, RJ Smith, RM Gold, RP Vertes, RP Vertes, RP Waters, RY Moore, S Cabib, S Cohen, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Fanous, S Geisler, S Grimwood, S Shiffman, S Stopponi, S Stopponi, S Stopponi, S Tobin, S Tobin, SA Flavin, SE Back, SF Maier, SF Maier, SG Nair, SG Nair, SG Nair, SH Ahmed, SH Ahmed, SL Grella, SM Antelman, SO Eans, SR Bornstein, SR Sesack, SV Mahler, SV Mahler, T Holdstock, T Maric, TL Bale, TR Kosten, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, UE Ghitza, V Deroche, VA Redila, WA Hunt, WB Cannon, WM Meil, X Liu, X Liu, X Wang, Y Buczek, Y Figueroa-Guzman, Y Nawata, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Silberman, Y Zhao, Yavin Shaham, YW Chen, YY Ma, YY Ma, Z Sarnyai, ZJ Brown, ZJ Brown, ZX Xi   +291 more
core   +2 more sources