Results 41 to 50 of about 25,416 (201)

Addiction‐related problems in Japan: A regional perspective

Addiction, EarlyView.
Abstract Japan's addiction landscape appears paradoxical. The lifetime use of illicit drugs is among the lowest in Organisation for Economic Cooperation and Development countries, but harm from alcohol, tobacco, and gambling ranks among the world's highest.
Soichiro Ide, Yoko Nishitani, Masahiko Sumitani, Masabumi Minami, Tadashi Isa, Masako Iseki, Michiko Ohkura, Hitoshi Okamoto, Tetsuro Kikuchi, Yuko Sekino, Hidehiko Takahashi, Kenji Takeuchi, Atsumi Nitta, Takeshi Honjo, Hiroshi Matsumoto, Tsuyoshi Miyakawa, Toshiya Murai, Toshihiko Matsumoto, Kazuyuki Nakagome, Kazutaka Ikeda   +19 more
wiley   +1 more source

Protective Effect of Exercise on Liver Oxidative Stress, Inflammation and Histopathological Changes after Morphine Withdrawal in ‎Rats

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: The harmful effects of morphine on the liver after withdrawal syndrome are unclear. In this experiment, we investigated the effects of exercise on oxidative stress, liver inflammation, liver enzymes, and liver histology after ...
Ebrahim Abbasi, iraj salehi, Ebrahim Zarin Kalam, Kamal Ranjbar, Fatemeh Mirzaei, Alireza Komaki, Sara Soleimani Asl   +6 more
doaj  

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, EarlyView.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source

Navigating pregnancy and addiction recovery: Patient perspectives on perinatal care interventions for women with opioid use disorder in Kentucky, USA

Addiction, EarlyView.
Abstract Background and aims The state of Kentucky has been heavily impacted by the ongoing opioid crisis in the United States, with high overdose mortality, high prevalence of opioid use disorder (OUD), elevated maternal mortality and incidence of Neonatal Abstinence Syndrome.
Hilary L. Surratt, Olivia A. Davis, Elizabeth O. Nelson, Hayley Durr, Karen Fawcett, Jason Joy, Brandon L. Schanbacher, Marie Vice, John A. Bauer, Wendy F. Hansen   +9 more
wiley   +1 more source

Role of calcium in morphine dependence and naloxone-precipitated withdrawal in mice

Journal of Experimental Pharmacology, 2011
Vikas Seth, Prerna Upadhyaya, Vijay Moghe, Mushtaq AhmadDepartment of Pharmacology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, IndiaPurpose: To explore the role of calcium in morphine withdrawal syndrome using various agents affecting calcium ...
Vikas Seth, Prerna Upadhyaya, Vijay Moghe, et al   +3 more
doaj  

Rare but relevant: Ibogaine and cardiovascular complications—prolonged QT interval and ventricular arrhythmias

Addiction, EarlyView.
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley   +1 more source

Effect of Morphine Withdrawal Syndrome on Cerebral Ischemia [PDF]

Iranian Journal of Basic Medical Sciences, 2011
Objective(s)Opioid abuse is still remained a major mental health problem, a criminal legal issue and may cause ischemic brain changes including stroke and brain edema.
Mohammad Allahtavakoli, Ruhollah Moloudi, Mohammad Ebrahim Rezvani, , Ali Shamsizadeh   +3 more
doaj  

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, EarlyView.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Impact of antibiotic-induced gut microbiota modulation on morphine analgesia, tolerance, withdrawal, and neurophysiological changes in mice

Scientific Reports
Morphine, a potent opioid analgesic, is limited in clinical use due to tolerance, dependence, and withdrawal. Recent research highlights the gut microbiota as a crucial regulator of opioid effects through the microbiota-gut-brain axis.
Zahra Jokar, Somayeh Shahidani, Parham Reisi, Hojjatallah Alaei, Mohammad Sadegh Damavandi, Hossein Khanahmad   +5 more
doaj   +1 more source

Ascorbic acid effect on morphine withdrawal symptoms in rats

Journal of Craniomaxillofacial Research, 2021
Introduction: Today, drug addiction is an important healthcare issue. Any helps to drug withdrawal may decrease its prevalence in the society. Ascorbic acid is a component, which can affect neurotransmitter systems as a regulator along with its ...
Abdollah Farhadi Nasab, Safoura Raoufi, Naghmeh Bahrami   +2 more
doaj