Results 151 to 160 of about 8,186 (190)

Evolutionary Perspective of Nonclassical MHC Class I and Innate-like T Cells Relevance in Immune Surveillance. [PDF]

Cells
Robert J, Najafi-Majd E.
europepmc   +1 more source

Antibiotic use in early life impairs MAIT cell-mediated immunity in adulthood. [PDF]

J Exp Med
LeBlanc GR, Sobel AL, Melamed J, Haas D, Ansaldo E, Cirone AM, Murguia E, Constantinides MG.   +7 more
europepmc   +1 more source

Caregiver and healthcare professional perspectives on drivers of routine immunisation uptake in East New Britain, Papua New Guinea: a qualitative study. [PDF]

BMJ Public Health
Dalton M, Pomat W, Sanderson B, Melepia P, James HA, Burangat D, Duwaba L, Willie D, Paivu B, Kiromat P, Stanley E, Waramin E, Laman M, Walker S, Homer C, Robinson LJ, Scoullar MJL, Vaccher S, Danchin M.   +18 more
europepmc   +1 more source

Mucosal-Associated Invariant T (MAIT) Cells in Skin Immunity: Metabolic Regulation, Tissue Adaptation, and Roles in Skin Inflammation and Disease. [PDF]

JID Innov
Nanda N, Kim C, Jain I, Cai C, Alphonse MP.   +4 more
europepmc   +1 more source

A Complex Neurodevelopmental Phenotype Resembling a Chromatinopathy With Concurrent 7p Duplication and 10p Deletion Involving ZMYND11: A Case Report and Literature Review. [PDF]

Mol Genet Genomic Med
Minale EMP, Martone S, Criscuolo C, Marra R, Lasorsa VA, Ruggiero R, Suero T, Capasso M, Andolfo I, Iolascon A, Russo R, Pinelli M.   +11 more
europepmc   +1 more source

MR1 antigen presentation to MAIT cells and other MR1-restricted T cells

Nature Reviews Immunology, 2023
MHC antigen presentation plays a fundamental role in adaptive and semi-invariant T cell immunity. Distinct MHC molecules bind antigens that differ in chemical structure, origin and location and present them to specialized T cells. MHC class I-related protein 1 (MR1) presents a range of small molecule antigens to MR1-restricted T (MR1T) lymphocytes. The
Hamish E G Mcwilliam, JOSÉ A Villadangos, Villadangos JOSÉ A   +2 more
exaly   +5 more sources

Establishment of an MR1 Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands

Journal of Medicinal Chemistry, 2023
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are modulated by ligands presented on MHC class I-related proteins (MR1). These cells have attracted attention as potential drug targets because of their involvement in the initial response to infection and various disorders.
Takuro Matsuoka, Akira Hattori, Shinya Oishi, Mitsugu Araki, Biao Ma, Toshiki Fujii, Norihito Arichi, Yasushi Okuno, Hideaki Kakeya, Sho Yamasaki, Hiroaki Ohno, Shinsuke Inuki   +11 more
core   +8 more sources