Results 11 to 20 of about 485,078 (155)
The EDC4‐XRN1 interaction controls P‐body dynamics to link mRNA decapping with decay [PDF]
EMBO Journal, 2023 William R Brothers +2 more
exaly +2 more sources
Eukaryotic mRNA decapping factors: molecular mechanisms and activity [PDF]
FEBS Journal, 2023 Allan Jacobson
exaly +2 more sources
mRNA-Decapping Associated DcpS Enzyme Controls Critical Steps of Neuronal Development. [PDF]
Cerebral Cortex, 2022 Megerditch Kiledjian +2 more
exaly +2 more sources
mRNA decapping: finding the right structures [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2018 Marc Graille, Clement Charenton
exaly +2 more sources
eLife, 2022 A single Dcp1–Dcp2 decapping enzyme targets diverse classes of yeast mRNAs for decapping-dependent 5′ to 3′ decay, but the molecular mechanisms controlling mRNA selectivity by the enzyme remain elusive.
Feng He, Chan Wu, Allan Jacobson
doaj +1 more source
The DEAD-box protein Dhh1 promotes decapping by slowing ribosome movement. [PDF]
PLoS Biology, 2012 Translational control and messenger RNA (mRNA) decay represent important control points in the regulation of gene expression. In yeast, the major pathway for mRNA decay is initiated by deadenylation followed by decapping and 5'-3' exonucleolytic ...
Thomas Sweet +2 more
doaj +1 more source
Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation. [PDF]
Nat Chem Biol, 2021 Cells organize biochemical processes into biological condensates. P-bodies are cytoplasmic condensates that are enriched in enzymes important for mRNA degradation and have been identified as sites of both storage and decay.
Tibble RW +4 more
europepmc +2 more sources
mRNA decapping in Saccharomyces cerevisiae
, 2000 The major pathway of mRNA degradation in yeast occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body. The products of the DCP1 and DCP2 genes are required for mRNA decapping.
Dunckley, Travis Lee
core +4 more sources
mBio, 2022 Decapping enzymes remove the 5′ cap of eukaryotic mRNA, leading to accelerated RNA decay. They are critical in regulating RNA homeostasis and play essential roles in many cellular and life processes.
Shuai Cao +4 more
doaj +1 more source
Zdorovʹe Rebenka, 2022 This scientific review deals with the mechanisms of action of cytoplasmic microRNAs, namely post-transcriptional silencing: recruitment of the DCP1-DCP2 decapping complex and disruption of the interaction of mRNA with ribosomes.
A.E. Abaturov, V.L. Babуch
doaj +1 more source