Results 31 to 40 of about 485,078 (155)
The Mimivirus L375 Nudix enzyme hydrolyzes the 5' mRNA cap.
PLoS ONE, 2021 The giant Mimivirus is a member of the nucleocytoplasmic large DNA viruses (NCLDV), a group of diverse viruses that contain double-stranded DNA (dsDNA) genomes that replicate primarily in eukaryotic hosts.
Grace Kago, Susan Parrish
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Interactions between Upf1 and the decapping factors Edc3 and Pat1 in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2011 In Saccharomyces cerevisiae, mRNA transcripts with premature termination codons are targeted for deadenylation independent decapping and 5' to 3' decay in a quality control pathway termed nonsense-mediated decay (NMD).
Kylie D Swisher, Roy Parker
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Regulation of processing body formation in the budding yeast "Saccharomyces cerevisiae" [PDF]
, 2014 The life cycle of mRNA, from transcription to decay, is a tightly regulated biological process. mRNA is an essential molecule that the cell utilizes to alter gene expression. Degradation is one process through which the cell can regulate mRNA levels.
Weidner, Julie
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Biology Open, 2016 The rate and regulation of mRNA decay are major elements in the proper control of gene expression. Edc3 and Lsm4 are two decapping activator proteins that have previously been shown to function in the assembly of RNA granules termed P bodies.
Susanne Huch +5 more
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mRNA Decapping Factors LSM1 and PAT Paralogs Are Involved in Turnip Mosaic Virus Viral Infection
Molecular Plant-Microbe Interactions, 2022 Turnip mosaic virus is a devastating potyvirus infecting many economically important brassica crops. In response to this, the plant host engages its RNA silencing machinery, involving AGO proteins, as a prominent strategy to restrain turnip mosaic virus (
Zhangli Zuo +3 more
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Functional Link between the Mammalian Exosome and mRNA Decapping [PDF]
, 2001 Mechanistic understanding of mammalian mRNA turnover remains incomplete. We demonstrate that the 3′ to 5′ exoribonuclease decay pathway is a major contributor to mRNA decay both in cells and in cell extract.
Kiledjian, Megerditch, Wang, Zuoren
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HPat a decapping activator interacting with the miRNA effector complex.
PLoS ONE, 2013 Animal miRNAs commonly mediate mRNA degradation and/or translational repression by binding to their target mRNAs. Key factors for miRNA-mediated mRNA degradation are the components of the miRNA effector complex (AGO1 and GW182) and the general mRNA ...
Elisabeth Barišić-Jäger +4 more
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The 'scavenger' m(7)GpppX pyrophosphatase activity of Dcs1 modulates nutrient-induced responses in yeast [PDF]
, 2004 Dcs1, the m(7)GpppX pyrophosphatase of Saccharomyces cerevisiae, has been reported to 'scavenge' capped 51 end fragments generated by 3'-->5' mRNA degradation.
Miyan, J +10 more
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Wellcome Open Research, 2021 Background: RNA binding proteins play crucial role in determining if a given mRNA will be translated, stored, or degraded. Sbp1 is an RGG-motif containing protein that is implicated in affecting mRNA decapping and translation.
Nupur Bhatter +3 more
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Xp54 and related (DDX6-like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation [PDF]
, 2006 The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational ...
Weston, A, Sommerville, John
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