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Regulation of local mRNA translation
Current Opinion in Cell Biology, 2004Regulated local mRNA translation is one mechanism cells employ to concentrate proteins in particular locations. However, cells use many different strategies to accomplish this task; for example, some mRNAs are destroyed in regions where they are not wanted, other mRNAs are repressed in areas where their translation would be deleterious, and yet other ...
Yi-Shuian, Huang, Joel D, Richter
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mRNA translational control of regeneration
Current Opinion in Genetics & DevelopmentmRNA translation is rapidly upregulated after injury to supply proteins required for tissue regeneration. Augmented protein synthesis during regeneration has long been associated with increases in ribosome biogenesis and mTORC1 activity. Emerging evidence highlights the roles of multiple signaling pathways, RNA-binding proteins, and RNA modifications ...
Mehdi, Amiri +2 more
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mTORC1 signalling and mRNA translation
Biochemical Society Transactions, 2009Signalling through mTORC1 (mammalian target of rapamycin complex 1) is important in controlling many cell functions, including protein synthesis, which it activates. mTORC1 signalling is activated by stimuli which promote protein accumulation such as anabolic hormones, growth factors and hypertrophic stimuli.
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mRNA translation in stress granules is not uncommon
Nature Reviews Molecular Cell Biology, 2021Kim Baumann, Baumann Kim
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Tagging insulin mRNA for translation
Nature Structural & Molecular Biology, 2023openaire +2 more sources
Intracellular mRNA transport and localized translation
Nature Reviews Molecular Cell Biology, 2021Sulagna Das +2 more
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De-centralizing the Central Dogma: mRNA translation in space and time
Molecular Cell, 2023André Schwarz
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Initiation of mRNA translation in prokaryotes
Biochemistry, 1990C O, Gualerzi, C L, Pon
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The plasticity of mRNA translation during cancer progression and therapy resistance
Nature Reviews Cancer, 2021Lucilla Fabbri +2 more
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