Results 11 to 20 of about 162,270 (298)
From COVID-19 to Cancer mRNA Vaccines: Moving From Bench to Clinic in the Vaccine Landscape
Frontiers in Immunology, 2021 Recently, mRNA vaccines have become a significant type of therapeutic and have created new fields in the biopharmaceutical industry. mRNA vaccines are promising next-generation vaccines that have introduced a new age in vaccinology.
Chiranjib Chakraborty +4 more
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Advanced Drug Delivery Reviews, 2021 mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology, and nanotechnology have generated interest in delivering safe and effective mRNA therapeutics. In this review, we discuss design and self-assembly of mRNA vaccines.
Kim, Jeonghwan +3 more
openaire +2 more sources
Journal of Genetics and Genomics, 2021 The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two mRNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive
Huang, Qingrui +2 more
openaire +2 more sources
Nanotechnology-Enabled COVID-19 mRNA Vaccines
Encyclopedia, 2021 COVID-19 mRNA vaccines contain synthetic mRNA sequences encoded for the Spike proteins expressed on the surface of SARS-CoV-2, and utilize the host cells to produce specific antigens that stimulate both humoral and cellular immunities.
Yu Gao +3 more
doaj +1 more source
Production of a subunit vaccine candidate against porcine post-weaning diarrhea in high-biomass transplastomic tobacco [PDF]
, 2012 Post-weaning diarrhea (PWD) in piglets is a major problem in piggeries worldwide and results in severe economic losses. Infection with Enterotoxigenic Escherichia coli (ETEC) is the key culprit for the PWD disease.
Cox, Eric +5 more
core +11 more sources
From mRNA sensing to vaccines [PDF]
Immunity, 2021 The 2005 Immunity paper by Karikó et al. has been hailed as a cornerstone insight that directly led to the design and delivery of the mRNA vaccines against COVID-19. We asked experts in pathogen sensing, vaccine development, and public health to provide their perspective on the study and its implications.
Fauci, Anthony S. +8 more
openaire +2 more sources
Development and Delivery Systems of mRNA Vaccines
Frontiers in Bioengineering and Biotechnology, 2021 Since the outbreak of SARS-CoV-2, mRNA vaccine development has undergone a tremendous drive within the pharmaceutical field. In recent years, great progress has been made into mRNA vaccine development, especially in individualized tumor vaccines.
Yongjun Liang, Liping Huang, Tiancai Liu
doaj +1 more source
Progress and challenges of mRNA vaccines
Interdisciplinary Medicine, 2023 Messenger RNA (mRNA) vaccines are third‐generation nucleic acid vaccines developed after first‐generation inactivated and live‐attenuated vaccines and second‐generation subunit and viral vector vaccines, characterized by a rapid response to pathogen ...
Liangru Lin +3 more
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Developing mRNA-vaccine technologies [PDF]
RNA Biology, 2012 mRNA vaccines combine desirable immunological properties with an outstanding safety profile and the unmet flexibility of genetic vaccines. Based on in situ protein expression, mRNA vaccines are capable of inducing a balanced immune response comprising both cellular and humoral immunity while not subject to MHC haplotype restriction.
Thomas, Schlake +3 more
openaire +2 more sources
mRNA vaccine in cancer therapy: Current advance and future outlook
Clinical and Translational Medicine, 2023 Messenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that have shown great promise in the immunotherapy of a wide variety of infectious diseases and cancer.
Youhuai Li +10 more
doaj +1 more source