Results 11 to 20 of about 11,376 (201)
Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione [PDF]
Metal-responsive transcription factor 1 (MTF-1) regulates expression of its target genes in response to various stress conditions, notably heavy metal load, via binding to metal response elements (MREs) in the respective enhancer/promoter regions. Furthermore, it serves a vital function in embryonic liver development. However, targeted deletion of Mtf1
Walter Schaffner
exaly +4 more sources
The "metal transcription factor" MTF-1: biological facts and medical implications
Metallothioneins (MTs) are a class of small, cysteine-rich proteins that have an important function in heavy metal metabolism and detoxification and in the management of various forms of cell stress. Several lines of evidence suggest a role for metallothioneins in therapy resistance of malignant tumours, regulation of blood pressure and protection ...
P Lichtlen, W Schaffner
doaj +3 more sources
Ameliorative effects of combination therapy with metformin and crocin in experimental colitis in rats [PDF]
Background and purpose: Inflammatory bowel disease (IBD) is characterized by aberrant immune responses in the colon, leading to the inflammatory cascades.
Bahare Koohshekan +3 more
doaj +2 more sources
Objective. To carry out a retrospective analysis of the restoration of the anterior and posterior vertebral body heights and the elimination of deformation of the anterior spinal canal wall caused by thoracic and lumbar spine injury, based on the data of
Vladimir D. Usikov +2 more
doaj +1 more source
Metal-regulatory transcription factor-1 (MTF-1) is of importance in maintaining metal homeostasis. Copper exposure considerably stimulates the proliferation of hepatocellular carcinoma (HCC) cells with enhanced MTF-1 expression.
Zhuozhen Lyu +4 more
doaj +1 more source
Divalent metal‐dependent regulation of hepcidin expression by MTF‐1 [PDF]
Hepcidin is a small acute phase peptide that regulates iron absorption. It is induced by inflammation and infection, but is repressed by anaemia and hypoxia. Here we further reveal that hepcidin transcription also involves interactions between functional metal response elements (MREs) in its promoter, and the MRE‐binding transcription factor‐1 ...
Balesaria, Sara +4 more
openaire +2 more sources
AN IMPROVED HIGH FREQUENCY MODULATING FUSION METHOD BASED ON MODULATION TRANSFER FUNCTION FILTERS [PDF]
GeoEye-1 is the most advanced and highest resolution commercial earth imaging satellite in the world today. It provides multispectral images (MS) and Panchromatic image (PAN) with spatial resolutions of 2.0 m and 0.5 m respectively.
Y. Jia, M. Wu, X. Zhang
doaj +1 more source
Introduction The more accurate is the measurement of the parameters for correcting the deformity of damaged spinal segments the more accurate will be the restoration of the sagittal profile and original anatomy of the spine.
Vladimir D. Usikov +2 more
doaj +1 more source
In this study, we developed a numerical model of the coupled modulation transfer function (coupled-MTF) based on the discrete sampling system from the perspective of optical system imaging quality evaluation for coupled two-dimensional discrete sampling ...
Wenxian Li +4 more
doaj +1 more source
Crystal engineering and, more specifically, the development of multicomponent materials has become an effective technique to rationally modify important physicochemical properties of solids, such as solubility and thermal stability.
Cristóbal Verdugo-Escamilla +4 more
doaj +1 more source

