Results 11 to 20 of about 462,631 (250)
Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump. [PDF]
MBio, 2019 Acinetobacter baumannii is a successful human pathogen which has emerged as one of the most problematic and highly antibiotic-resistant Gram-negative bacteria worldwide. Multidrug efflux is a major mechanism that A.
Edward W Yu +2 more
exaly +3 more sources
Multidrug Efflux Pumps in Bacteria and Efflux Pump Inhibitors
Postępy Mikrobiologii, 2022 Antimicrobial resistance is becoming a paramount health concern nowadays. The increasing drug resistance in microbes is due to improper medications or over usage of drugs. Bacteria develop many mechanisms to extrude the antibiotics entering the cell. The
Sreekantan Abhirami P. +3 more
doaj +2 more sources
Antimicrobial and efflux pump inhibitory activity of caffeoylquinic acids from Artemisia absinthium against gram-positive pathogenic bacteria. [PDF]
PLoS ONE, 2011 BACKGROUND:Traditional antibiotics are increasingly suffering from the emergence of multidrug resistance amongst pathogenic bacteria leading to a range of novel approaches to control microbial infections being investigated as potential alternative ...
Yiannis C Fiamegos +8 more
doaj +4 more sources
Identification of a multidrug efflux pump in Flavobacterium johnsoniae [PDF]
Veterinary Research, 2009 In this study, the mechanism conferring multiple drug resistance in several strains of flavobacteria isolated from the ovarian fluids of hatchery reared 3-year old brook trout Salvelinus fontinalis was investigated.
Brooke A. Jude +7 more
core +4 more sources
Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump. [PDF]
PLoS ONE, 2014 Neisseria gonorrhoeae is an obligate human pathogen and the causative agent of the sexually-transmitted disease gonorrhea. The control of this disease has been compromised by the increasing proportion of infections due to antibiotic-resistant strains ...
Jani Reddy Bolla +11 more
doaj +3 more sources
The nature and epidemiology of OqxAB, a multidrug efflux pump. [PDF]
Antimicrob Resist Infect Control, 2019 Background OqxAB efflux pump has been found to mediate multidrug resistance (MDR) in various bacteria over the past decades. The updates on the nature and epidemiology of OqxAB efflux pump need to be fully reviewed to broaden our understanding of this ...
Li J +6 more
europepmc +6 more sources
Microbial Primer: Multidrug efflux pumps [PDF]
Microbiology, 2023 Multidrug efflux pumps are molecular machines that sit in the bacterial cell membrane and pump molecules out from either the periplasm or cytoplasm to outside the cell.
Blair, Jessica M A; id_orcid +3 more
core +3 more sources
UMYU Journal of Microbiology ResearchKlebsiella pneumoniae causes diverse healthcare- and community-associated infections, frequently affecting patients with indwelling medical devices. Its ability to form biofilms and activate efflux pumps enhances antibiotic resistance.
Hadiza Na`iya Misbahu +7 more
doaj +2 more sources
Physiological Functions of Bacterial “Multidrug” Efflux Pumps [PDF]
Chemical Reviews, 2021 Bacterial multidrug efflux pumps have come to prominence in human and veterinary pathogenesis because they help bacteria protect themselves against the antimicrobials used to overcome their infections. However, it is increasingly realized that many, probably most, such pumps have physiological roles that are distinct from protection of bacteria against
Peter J. F. Henderson +5 more
openaire +4 more sources
Interplay between three RND efflux pumps in doxycycline-selected strains of Burkholderia thailandensis. [PDF]
PLoS ONE, 2013 BACKGROUND: Efflux systems are involved in multidrug resistance in most Gram-negative non-fermentative bacteria. We have chosen Burkholderia thailandensis to dissect the development of multidrug resistance phenotypes under antibiotic pressure ...
Fabrice Vincent Biot +9 more
doaj +1 more source