Results 181 to 190 of about 262,601 (237)

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju, HeeJae Choi, Shilpa Madari, Annie Carlisle, Ashish Sharma, Christina Kunz, Fenglei Huang   +6 more
wiley   +1 more source

Contribution of RND superfamily multidrug efflux pumps AdeABC, AdeFGH, and AdeIJK to antimicrobial resistance and virulence factors in multidrug-resistant <i>Acinetobacter baumannii</i> AYE. [PDF]

Antimicrob Agents Chemother
Xie L, Li J, Peng Q, Liu X, Lin F, Dai X, Ling B.   +6 more
europepmc   +1 more source

Limonene‐Rich Citrus sinensis Essential Oil Modulates Antimicrobial Resistance and Virulence Traits of Foodborne Pseudomonas aeruginosa: Mechanistic Evidence and Validation in Fresh‐Produce System

Journal of Food Safety, Volume 46, Issue 5, October 2026.
Limonene‐rich Citrus sinensis essential oil (CS‐EO) exhibited antibacterial and antivirulence activity against Pseudomonas aeruginosa, affecting membrane integrity, antimicrobial susceptibility, motility, biofilm formation, and pyocyanin production.
Luana de Carvalho, Mariana Lima Braga Pereira, Matheus Henrique Nogueira, André Ricardo Peron dos Santos, Mikaella Nascimento da Silva, Kamilly Santana Cazotto, Márcia Cristina Furlaneto, Luciana Furlaneto Maia   +7 more
wiley   +1 more source

Phylogenetic and Structural Analysis of Miconazole Susceptibility in Malassezia pachydermatis Isolates From Dogs With Otitis Externa

Veterinary Dermatology, Volume 37, Issue 5, Page 620-629, October 2026.
Background: An increased number of dogs with unresolved yeast otitis externa (OE) after miconazole treatment was observed at a tertiary practice. Hypothesis/Objectives: To evaluate miconazole susceptibility in Malassezia pachydermatis isolates from canine OE.
Cole M. Belcher, Clarissa P. Souza, Elyas McGuire, Chien‐Che Hung, Joel D. A. Tyndall, Lois L. Hoyer   +5 more
wiley   +1 more source

Fitness trade-offs of multidrug efflux pumps in Escherichia coli K-12 in acid or base, and with aromatic phytochemicals. [PDF]

Appl Environ Microbiol
Liu Y, Van Horn AM, Pham MTN, Dinh BNN, Chen R, Raphael SDR, Paulino A, Thaker K, Somadder A, Frost DJ, Menke CC, Slimak ZC, Slonczewski JL.   +12 more
europepmc   +1 more source

A New Sustainable Approach to Antibiotic Resistance: Development of bis‐Quaternary Ammonium Salts From 2,4,6‐Trichloro‐1,3,5‐Triazine

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Antibiotics improved human life, but bacterial resistance makes surfaces and packaging disinfection critical. Quaternary ammonium salts (QAS) represent a possible alternative. In this work, new bis‐cationic QAS from 2,4,6‐trichloro‐1,3,5‐triazine (bis‐TQAS) were synthesized, showing excellent inhibition against Klebsiella pneumoniae, Escherichia coli ...
Rachele Rampazzo, Arianna De Luca, Manuela Facchin, Patrizio Raffa, Andrea Gattolin, Valentina Beghetto   +5 more
wiley   +1 more source

Novel Inducers of the Expression of Multidrug Efflux Pumps That Trigger Pseudomonas aeruginosa Transient Antibiotic Resistance. [PDF]

Antimicrob Agents Chemother, 2019
Laborda P, Alcalde-Rico M, Blanco P, Martínez JL, Hernando-Amado S.   +4 more
europepmc   +1 more source

Kinetic Control of Quorum Sensing in Pseudomonas aeruginosa by Multidrug Efflux Pumps. [PDF]

ACS Infect Dis, 2018
Wolloscheck D, Krishnamoorthy G, Nguyen J, Zgurskaya HI.   +3 more
europepmc   +1 more source

Inverted Regulation of Multidrug Efflux Pumps, Acid Resistance, and Porins in Benzoate-Evolved Escherichia coli K-12. [PDF]

Appl Environ Microbiol, 2019
Moore JP, Li H, Engmann ML, Bischof KM, Kunka KS, Harris ME, Tancredi AC, Ditmars FS, Basting PJ, George NS, Bhagwat AA, Slonczewski JL.   +11 more
europepmc   +1 more source

Magnitude of Voriconazole Resistance in Clinical and Environmental Isolates of Aspergillus flavus and Investigation into the Role of Multidrug Efflux Pumps. [PDF]

Antimicrob Agents Chemother, 2018
Paul RA, Rudramurthy SM, Dhaliwal M, Singh P, Ghosh AK, Kaur H, Varma S, Agarwal R, Chakrabarti A.   +8 more
europepmc   +1 more source