Results 11 to 20 of about 21,341,984 (280)
Natural history and 12-month progression of multiple system atrophy in a Chinese cohort. [PDF]
BMC NeurolBackground Understanding disease natural history is important for the development of potential treatments for people with MSA. We describe the natural progression of early MSA in a Chinese population.
Feng T +15 more
europepmc +2 more sources
Tremor in Multiple System Atrophy - a review
Tremor and Other Hyperkinetic Movements, 2013 Background: Multiple system atrophy (MSA) is a rare neurodegenerative movement disorder characterized by a rapidly progressive course. The clinical presentation can include autonomic failure, parkinsonism, and cerebellar signs.
Christine Kaindlstorfer +2 more
doaj +5 more sources
Posterior fossa arachnoid cysts in multiple system atrophy. [PDF]
IBRO Neurosci RepBackground: Multiple system atrophy (MSA) is an α-synucleinopathy characterized by prominent cerebellar or parkinsonian features. This is pathologically due to the deposition of α-synuclein in glial cells, the mechanism by which s not entirely clear.
Blazek Ramsay AM +3 more
europepmc +2 more sources
Medical Clinics of North America, 1999 MSA is a complex disorder, with regard to its pathology and cause as well as its clinical diagnosis and treatment. Although a number of clinical treatments may improve quality of life for these patients, given the widespread pathology present, symptomatic treatment, particularly that involving neurotransmitter replacement, is likely to remain difficult.
L, Swan, J, Dupont
+7 more sources
Seminars in Neurology, 2001 Multiple system atrophy (MSA) is an adult-onset sporadic progressive neurodegenerative disorder of unknown etiology. It is clinically characterized by the variable combination of autonomic failure, parkinsonism, cerebellar ataxia, and pyramidal signs. The present review summarizes up-to-date knowledge on the clinical diagnosis and molecular pathology ...
G K, Wenning +4 more
+7 more sources
S.S. Korsakov Journal of Neurology and Psychiatry, 2023 The article presents a progressive neurodegenerative disease — multisystem atrophy, characterized by a combination of autonomic failure and various motor disorders, including parkinsonism and/or cerebellar ataxia; etiopathogenetic factors and variants of the clinical picture are described.
M.P. Topuzova +8 more
openaire +5 more sources
Development of Therapies for Spinal Muscular Atrophy Using Gene Therapy and Nanotechnology [PDF]
, 2013 Spinal muscular atrophy (SMA) is a genetic disease which is characterized by muscle weakness and atrophy. The disease arises from mutations in the survival motor neuron 1 (SMN1) gene causing degeneration of spinal cord motor neurons.
Little, Daniel
core +6 more sources
Frontiers in Neurology, 2022 Multiple system atrophy (MSA) is a rare and progressive neurodegenerative disorder. Autonomic failure (AF) is one main clinical feature which has a significant impact on health-related quality of life.
Marc Kermorgant +13 more
doaj +1 more source
Cognitive Impairments in Multiple System Atrophy of the Cerebellar Type [PDF]
Journal of Movement Disorders, 2011 Background and Purpose We investigated the cognitive profiles in a large sample of patients with multiple system atrophy-cerebellar ataxia (MSA-C) and compared directly them in patients with clinical diagnosis of probable MSA-C without dementia and ...
Hyun J. Hong +4 more
doaj +1 more source
A Case of Multiple System Atrophy (MSA) – First Presentation in a Psychiatry Service [PDF]
, 2021 A 67 years old female developed cognitive deficits, depression and anxiety as first symptoms of multiple system atrophy (MSA). In the course of an year autonomic failure, parkinsonism and cerebellar ataxia also developed.
Andra Livia BRONESCU +2 more
core +2 more sources