Results 31 to 40 of about 133,873 (236)
The medial prefrontal cortex (mPFC) is a key brain region for the control of consummatory behavior. Neuronal activity in this area is modulated when rats initiate consummatory licking and reversible inactivations eliminate reward contrast effects and ...
Marc Alexander Parent +4 more
doaj +1 more source
Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of Drug-Receptor Binding [PDF]
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed.
Shizuo Yamada +3 more
doaj +1 more source
Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer +12 more
core +1 more source
The global trend of increasing mushroom consumption, combined with traditional practices in Romania and other Eastern European countries of collecting and consuming “wild mushrooms”, may contribute to the rising incidence of emergency presentations due ...
Bogdan Oprita +4 more
doaj +1 more source
Muscarinic acetylcholine receptors (mAChRs) are a pivotal constituent of the central and peripheral nervous system. Yet, therapeutic and diagnostic applications thereof are hampered by the lack of subtype selective ligands.
Marius Ozenil +8 more
doaj +1 more source
Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]
To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Delgado-Garcia, JM +2 more
core +1 more source
Paying attention to smell: Cholinergic signaling in the olfactory bulb.
The tractable, layered architecture of the olfactory bulb (OB), and its function as a relay between odor input and higher cortical processing, makes it an attractive model to study how sensory information is processed at a synaptic and circuit level. The
Rinaldo David D'Souza +1 more
doaj +1 more source
A short synthesis of (+)-muscarine from L-rhamnose which does not require the use of any protecting group is described.
Mantell, S, Fleet, G, Brown, D
openaire +2 more sources
Acetylcholine release and inhibitory interneuron activity in hippocampal CA1
Acetylcholine release in the central nervous system (CNS) has an important role in attention, recall and memory formation. One region influenced by acetylcholine is the hippocampus, which receives inputs from the medial septum and diagonal band of Broca ...
A. Rory McQuiston
doaj +1 more source
Repurposing Pilocarpine Hydrochloride for Treatment of
Acetylcholine modulates the virulence of Candida albicans and regulates an appropriate immune response to infection in a Galleria mellonella infection model. Indeed, the evidence suggests that C.
Christopher Nile +11 more
doaj +1 more source

