Results 31 to 40 of about 133,873 (236)

Cholinergic and ghrelinergic receptors and KCNQ channels in the medial PFC regulate the expression of palatability

open access: yesFrontiers in Behavioral Neuroscience, 2015
The medial prefrontal cortex (mPFC) is a key brain region for the control of consummatory behavior. Neuronal activity in this area is modulated when rats initiate consummatory licking and reversible inactivations eliminate reward contrast effects and ...
Marc Alexander Parent   +4 more
doaj   +1 more source

Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of Drug-Receptor Binding [PDF]

open access: yesInternational Neurourology Journal, 2012
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed.
Shizuo Yamada   +3 more
doaj   +1 more source

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]

open access: yes, 2013
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer   +12 more
core   +1 more source

Wild/Woodland Mushroom Poisoning: The Experience of Bucharest Emergency Hospital-Retrospective Study of ER 2023–2024 Presentations

open access: yesJournal of Fungi
The global trend of increasing mushroom consumption, combined with traditional practices in Romania and other Eastern European countries of collecting and consuming “wild mushrooms”, may contribute to the rising incidence of emergency presentations due ...
Bogdan Oprita   +4 more
doaj   +1 more source

Synthesis, Biological, and Computational Evaluation of Antagonistic, Chiral Hydrobenzoin Esters of Arecaidine Targeting mAChR M1

open access: yesPharmaceuticals, 2020
Muscarinic acetylcholine receptors (mAChRs) are a pivotal constituent of the central and peripheral nervous system. Yet, therapeutic and diagnostic applications thereof are hampered by the lack of subtype selective ligands.
Marius Ozenil   +8 more
doaj   +1 more source

Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]

open access: yes, 2005
To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Delgado-Garcia, JM   +2 more
core   +1 more source

Paying attention to smell: Cholinergic signaling in the olfactory bulb.

open access: yesFrontiers in Synaptic Neuroscience, 2014
The tractable, layered architecture of the olfactory bulb (OB), and its function as a relay between odor input and higher cortical processing, makes it an attractive model to study how sensory information is processed at a synaptic and circuit level. The
Rinaldo David D'Souza   +1 more
doaj   +1 more source

(+)-Muscarine from L-rhamnose

open access: yesJournal of the Chemical Society, Chemical Communications, 1991
A short synthesis of (+)-muscarine from L-rhamnose which does not require the use of any protecting group is described.
Mantell, S, Fleet, G, Brown, D
openaire   +2 more sources

Acetylcholine release and inhibitory interneuron activity in hippocampal CA1

open access: yesFrontiers in Synaptic Neuroscience, 2014
Acetylcholine release in the central nervous system (CNS) has an important role in attention, recall and memory formation. One region influenced by acetylcholine is the hippocampus, which receives inputs from the medial septum and diagonal band of Broca ...
A. Rory McQuiston
doaj   +1 more source

Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections

open access: yesmSphere, 2019
Acetylcholine modulates the virulence of Candida albicans and regulates an appropriate immune response to infection in a Galleria mellonella infection model. Indeed, the evidence suggests that C.
Christopher Nile   +11 more
doaj   +1 more source

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