Results 11 to 20 of about 8,003 (176)
Mycotoxins in Basidiomycete Mycelium and Fruiting Bodies: Implications for Eu Novel Food Assessment and Selected International Regulatory Frameworks. [PDF]
ABSTRACT Advances in technology have enabled the efficient and sustainable production of basidiomycete vegetative mycelium, particularly from Pleurotus species, as a novel food source. However, mycelium has yet to receive regulatory approval in many global markets, requiring a better understanding of factors affecting its safety.
Berglund NEW, Lankinen PV, Mikkonen KS.
europepmc +2 more sources
GABA receptor modulation of arcuate kisspeptin neuron bursting and synchronization activity in female mice. [PDF]
Abstract The arcuate nucleus kisspeptin (ARNKISS) neurons intermittently synchronize their activity to operate as the GnRH pulse generator and drive pulsatile reproductive hormone secretion in mammals. Although ARNKISS neurons are known to receive various GABAergic inputs, the effects of GABAA and GABAB receptor modulation on their ability to ...
Eddleston T, Morris PG, Herbison AE.
europepmc +2 more sources
GABAergic Neuron Activation in the RMTg-VTA Pathway Modulates Dopaminergic Neuron Excitability and Social Stress Susceptibility in Male Mice. [PDF]
In susceptible mice, dopamine neurons in the VTA exhibit increased excitability along with upregulation of GABAA receptors. Administration of the GABAA receptor agonist muscimol reduces this neuronal hyperexcitability and reverses social avoidance behavior.
Ma GY +11 more
europepmc +2 more sources
Experience-Dependent Effects of Muscimol-Induced Hippocampal Excitation on Mnemonic Discrimination
Memory requires similar episodes with overlapping features to be represented distinctly, a process that is disrupted in many clinical conditions as well as normal aging. Data from humans have linked this ability to activity in hippocampal CA3 and dentate
Sarah A. Johnson +9 more
doaj +1 more source
Effect of Histamine on Muscimol-Induced Working Memory Deficits in Radial Maze Performance
We investigated the participation of γ-aminobutyric acid (GABA) neurons of the medial septal area in eight-arm radial maze performance in rats. The intra-septal injection of muscimol, a GABAA agonist, caused an increase in total error and working memory ...
Yasuko Yamamoto +3 more
doaj +1 more source
Amanita muscaria: Ecology, Chemistry, Myths
Amanita muscaria is the most emblematic mushroom in the popular representation. It is an ectomycorrhizal fungus endemic to the cold ecosystems of the northern hemisphere.
Quentin Carboué, Michel Lopez
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Introduction:Â Neuropathic pain can be very difficult to treat and it is one of the important medical challenging about pain treatments. Muscimol as a new agonist of gamma-Aminobutyric acid receptor type A (GABAA) have been introduced for pain management.
Marjan Hosseini +6 more
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Exposure to acute intermittent hypoxia (AIH) induces prolonged increases (long term facilitation, LTF) in phrenic and sympathetic nerve activity (PhrNA, SNA) under basal conditions, and enhanced respiratory and sympathetic responses to hypoxia.
Daniela Ostrowski +10 more
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A simple RP-HPLC method was designed for the quantification of muscimol (5-(aminomethyl)-isoxazol-3-ol) present in five aqueous extracts of Amanita muscaria each from a different developmental stage.
Emersón León Ávila +1 more
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The neural mechanisms underlying alcohol dependence are not well-understood. GABAergic neurons in the ventral tegmental area (VTA) are a relevant target for ethanol.
Ashley C. Nelson +9 more
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