Results 31 to 40 of about 436,421 (289)

Smooth muscle cells largely develop independently of functional hemogenic endothelium

open access: yesStem Cell Research, 2014
Vascular smooth muscle cells represent a major component of the cardiovascular system. In vitro studies have shown that FLK1+ cells derived from embryonic stem (ES) cells can differentiate into both endothelial and smooth muscle cells.
Monika Stefanska   +4 more
doaj   +1 more source

Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice.

open access: yesPLoS ONE, 2014
Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth ...
Jintao Wang   +8 more
doaj   +1 more source

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

open access: yes, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Angelo Guglielmotti   +12 more
core   +3 more sources

Vascular smooth muscle caldesmon.

open access: yesJournal of Biological Chemistry, 1986
Caldesmon, a major actin- and calmodulin-binding protein, has been identified in diverse bovine tissues, including smooth and striated muscles and various nonmuscle tissues, by denaturing polyacrylamide gel electrophoresis of tissue homogenates and immunoblotting using rabbit anti-chicken gizzard caldesmon.
T Clark   +4 more
openaire   +3 more sources

Lack of α8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells

open access: yesBMC Cell Biology, 2010
Background Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The α8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells.
Hilgers Karl F   +9 more
doaj   +1 more source

Angiomyoma: An Unusual Diagnosis of Preauricular Swelling [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Angiomyoma is a benign tumour arising from smooth muscle of blood vessel walls. These tumours are usually found in the lower extremities presenting as a painful mass.
Anamika Kashyap   +2 more
doaj   +1 more source

Role of noncoding RNA in vascular remodelling [PDF]

open access: yes, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H.   +2 more
core   +1 more source

Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]

open access: yes, 2007
This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall.
Bolton, TB   +5 more
core   +3 more sources

Verapamil inhibits calcification and matrix vesicle activity of bovine vascular smooth muscle cells [PDF]

open access: yes, 2010
Calcium channel activity in vascular smooth muscle cells is a critical component during vascular calcification and formation of matrix vesicles. Here, we examined whether the blockade of L-type calcium channels inhibits these functions.
Chen, Neal X.   +4 more
core   +1 more source

CADASIL: A monogenic condition causing stroke and subcortical vascular dementia [PDF]

open access: yes, 2002
Mutations in Notch3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an inherited small vessel disease leading to subcortical strokes and vascular dementia. The phenotypic presentation
Dichgans, Martin
core   +1 more source

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