Results 31 to 40 of about 490,082 (308)
Calcium and Vascular Smooth Muscle Contraction [PDF]
Radioactive calcium flux in rabbit aorta was studied to evaluate factors regulating the movement of calcium into and out of the cell. Calcium content was estimated both from (1) the amount of 45 Ca present in the tissue and the specific activity of Ca in the bathing medium, and (2) determination of chemical calcium ...
Charles L. Seidel, David F. Bohr
openaire +3 more sources
A quantitative model for refilling of the sarcoplasmic reticulum during vascular smooth muscle asynchronous [Ca2+] oscillations [PDF]
We have developed a quantitative model for the creation of cytoplasmic Ca2+ gradients near the inner surface of the plasma membrane (PM). In particular we simulated the refilling of the sarcoplasmic reticulum (SR) via PM-SR junctions during asynchronous [Ca2+] oscillations in smooth muscle cells of the rabbit inferior vena cava.
arxiv +1 more source
Redox signaling, Nox5 and vascular remodeling in hypertension [PDF]
Purpose of review: Extensive data indicate a role for reactive oxygen species (ROS) and redox signaling in vascular damage in hypertension. However, molecular mechanisms underlying these processes remain unclear, but oxidative post-translational ...
De Lucca Camargo, Livia+5 more
core +1 more source
A model for the generation of localized transient Na+ elevations in vascular smooth muscle [PDF]
We present a stochastic computational model to study the mechanism of signalling between a source and a target ionic transporter, both localized on the plasma membrane (PM) and in intracellular nanometre-scale subplasmalemmal signalling compartments comprising the PM, the sarcoplasmic reticulum (SR), Ca2+ and Na+ transporters, and the intervening ...
arxiv +1 more source
Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth ...
Jintao Wang+8 more
doaj +1 more source
The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer+7 more
doaj +1 more source
Vascular smooth muscle caldesmon.
Caldesmon, a major actin- and calmodulin-binding protein, has been identified in diverse bovine tissues, including smooth and striated muscles and various nonmuscle tissues, by denaturing polyacrylamide gel electrophoresis of tissue homogenates and immunoblotting using rabbit anti-chicken gizzard caldesmon.
T Clark+4 more
openaire +3 more sources
Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]
<p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo+47 more
core +2 more sources
Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]
This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall.
Bolton, TB+5 more
core +3 more sources
Angiomyoma: An Unusual Diagnosis of Preauricular Swelling [PDF]
Angiomyoma is a benign tumour arising from smooth muscle of blood vessel walls. These tumours are usually found in the lower extremities presenting as a painful mass.
Anamika Kashyap+2 more
doaj +1 more source