Results 221 to 230 of about 347,517 (297)

Clock-Turning Control of P450 TxtE Regioselectivity Enables Precise Site Functionalization of Aromatic Compounds. [PDF]

JACS Au
Yang X, Pan Y, Miao T, Yuan Z, Cong Y, Fang B, Yan X, Zhang J, Chen R, Feng Y, Zhang Z, Gao B, Zhang L.   +12 more
europepmc   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Serine Mutation on Amicyanin Reveals Functional and Structural Roles of Asn47 and Asn54 in the Cu-Binding Ligand Containing Loop. [PDF]

J Microbiol Biotechnol
Kim E, Jeong H, Nam H, Jeoung S, Shin J, Choi M, Shin S.   +6 more
europepmc   +1 more source

Evaluation of gene editing in CHO cells using the Cas‐CLOVER system

Biotechnology Progress, EarlyView.
Abstract Recent advances in gene editing technologies have transformed the genetic engineering of Chinese hamster ovary (CHO) hosts, enabling the development of cell lines with improved stability and productivity. In this study, we employed the programmable nuclease (PN) Cas‐CLOVER to precisely target the Glutamine synthetase (GS) locus in CHO cells. A
Tiffany McLamarrah, Efecan Aral, Michael Hoffman, Jennifer Tedstone, Thomas King, Jason Vitko, Maria João Sebastião, Jose M. Escandell, Mafalda M. Dias, Iona McCall, Daniel Machado, Victor Cairns, Christine DeMaria, John J. Scarcelli   +13 more
wiley   +1 more source

Creation of an Engineered Oxygen-Insensitive L-Glutamate Oxidase for the Application of Electrochemical L-Glutamate Sensors. [PDF]

Int J Mol Sci
Hatada M, Takamatsu S, Asano R, Ikebukuro K, Tsugawa W, Sode K.   +5 more
europepmc   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Engineering a broad-spectrum glucose oxidase via substrate channel and linker design for enhanced lignocellulose bioconversion. [PDF]

Synth Syst Biotechnol
Feng Y, Chen X, Li Z, Ni Z, Wu Z, Guo Z, Sun F, Chen H, Chen H.   +8 more
europepmc   +1 more source

Artificial intelligence in enzyme catalysis: Emerging trends and applications in biocatalyst engineering

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales, Francisco Izaias da Silva Aires, Paulo Gonçalves de Sousa Junior, Calebe Da Rocha Silva, Emanuel Lino Rodrigues, Maria Cristiane Martins de Souza, José C. S. dos Santos   +6 more
wiley   +1 more source

Reprogramming Imine Reductases for Enantioselective Reduction of Electron-Rich Enamides. [PDF]

JACS Au
Liu XQ, Li R, Chen JL, Li Y, Wei L, Wu H, Li L, Chen BH, Wu Y, Liu SJ, Lin GX, Zhang JF, Zheng Y, Zhang C, Yang YF, Wang X, Chen P, Jia ZJ.   +17 more
europepmc   +1 more source

Primary charge separation in the reaction centers of Rhodobacter sphaeroides [PDF]

, 1990
Baltschewsky, M., Finkele, Ulrich, Holzapfel, Wolfgang, Kaiser, Wolfgang, Oesterhelt, Dieter, Scheer, Hugo, Stilz, Hans Ulrich, Zinth, Wolfgang   +7 more
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