Results 231 to 240 of about 349,101 (299)

S-SELeCT: a human-evolved serine integrase system for efficient large-cargo genome integration. [PDF]

Nucleic Acids Res
Farruggio AP, Jiang L, Duong K, Nguyen C, Kaddoura R, Tsai R.   +5 more
europepmc   +1 more source

Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo, Nagamani Vunnam, Jonathan N. Sachs, Benjamin J. Hackel   +3 more
wiley   +1 more source

Editing mitochondrial and chloroplast genomes : Genome editing technologies for plant organelles provide new opportunities in functional genomics and breeding. [PDF]

EMBO Rep
Forner J, Bock R.
europepmc   +1 more source

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

Biotechnology and Bioengineering, EarlyView.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn, Hannah K. Windsor, Zachary Schmitz, Nathaniel Cheung, Ebube Agwaramgbo, Benjamin J. Hackel   +5 more
wiley   +1 more source

Green bioconversion of insoluble chitin: chitinase development pathways via multi-strategy synergy. [PDF]

Bioresour Bioprocess
Sai ZP, Yin YR, Yang LQ, Wang JH, Yang XY, Liu FX, Jing X, Zhang Y, Li YD, Sang P, Yang ZF.   +10 more
europepmc   +1 more source

Site-Directed Mutagenesis in Escherichia coli of a Stable R772 [PDF]

Hille, Jacques, Kan, Jan van, Klasen, Ina, Schilperoort, Rob   +3 more
core  

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Mutation of a conserved anthranilate phosphoribosyltransferase active site residue supports tryptophan biosynthesis <i>in vivo</i>. [PDF]

MicroPubl Biol
Klepin S, Michalik B, Pillus L, Chik JK.
europepmc   +1 more source

Development of a transcription factor-based biosensor strain for reporting α-terpineol production <i>via</i> the alcohol-dependent hemiterpene pathway in <i>Escherichia coli</i>. [PDF]

RSC Chem Biol
Odhiambo CA, Ali IA, Williams GJ.
europepmc   +1 more source