ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves +3 more
wiley +1 more source
Identification of Ellagic Acid as a Natural GPR35 Agonist for Ulcerative Colitis Therapy. [PDF]
Liu H +7 more
europepmc +1 more source
The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains
ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell +4 more
wiley +1 more source
Multiple directed mutagenesis reduces enzymatic activity and antibody recognition of the African Swine Fever Virus E2 ubiquitin-conjugating protein (ASFV-pI215L). [PDF]
Jordão N +4 more
europepmc +1 more source
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
CRISPR-Cas Technology Turns Chlamydomonas reinhardtii into a Flagship for Algal Biotechnology. [PDF]
Antonacci A +6 more
europepmc +1 more source
Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz +2 more
wiley +1 more source
Cholesterol inhibits capsaicin activation of the TRPV1 channel. [PDF]
Brandwine-Shemmer T +3 more
europepmc +1 more source
Engineering an AlkS-PalkB Transcription Factor-Based Biosensor With Improved Sensitivity to Isobutanol and Other Short-Chain Alcohols. [PDF]
Chen J +5 more
europepmc +1 more source
Defining the role of <i>Pseudomonas aeruginosa</i> PilY1 in signaling and virulence. [PDF]
Pritchett CL, Damron FH, Barbier M.
europepmc +1 more source

