Results 51 to 60 of about 5,198 (143)

The Prediction of the Expected Current Selection Coefficient of Single Nucleotide Polymorphism Associated with Holstein Milk Yield, Fat and Protein Contents [PDF]

Asian-Australasian Journal of Animal Sciences, 2016
Milk-related traits (milk yield, fat and protein) have been crucial to selection of Holstein. It is essential to find the current selection trends of Holstein. Despite this, uncovering the current trends of selection have been ignored in previous studies.
Young-Sup Lee, Donghyun Shin, Wonseok Lee, Mengistie Taye, Kwanghyun Cho, Kyoung-Do Park, Heebal Kim   +6 more
doaj   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Reduced expression of mutS homolog 2 and mutL homolog 1 affects overall survival in laryngeal squamous cell carcinoma patients: Investigation into a potential cause

Oncology Reports, 2013
The risk factors affecting the survival rates of laryngeal carcinoma are not well understood. In this study, we investigated the expression status of mutS homolog 2 (MSH2) and mutL homolog 1 (MLH1) and examined the relationship between these two molecules and overall survival rates in laryngeal cancer.
Hong-Li, Gong, Yong, Shi, Yi, Shi, Chun-Ping, Wu, Peng-Yu, Cao, Liang, Zhou, Chen, Xu   +6 more
openaire   +3 more sources

Incidental Colorectal Adenomas in Adolescents: Clinical Management, Genetic Evaluation, and Surveillance

Journal of Gastroenterology and Hepatology, EarlyView.
Adolescents with incidental colorectal adenomas require age‐conscious management balancing referral for genetic counseling with evidence‐based surveillance. This narrative review proposes a pragmatic clinical algorithm integrating adenoma characteristics, hereditary risk assessment, and guideline‐concordant follow‐up to support individualized ...
Brett J. Hoskins, Shlomi Cohen, Colleen B. Flahive, Isabel Rojas, Aparajita Singh, Thomas M. Attard   +5 more
wiley   +1 more source

Spontaneous regression of advanced transverse colon cancer with deficient mismatch repair: a case report

Surgical Case Reports, 2023
Background Spontaneous regression (SR) of cancer occurs in 1 in 60,000–100,000 patients. This phenomenon has been reported in almost all cancer types, most commonly neuroblastoma, renal cell carcinoma, malignant melanoma, and lymphoma/leukemia.
Shinnosuke Harata, Hiroki Takahashi, Nanako Ando, Akira Kato, Kaori Watanabe, Takeshi Yanagita, Takuya Suzuki, Hajime Ushigome, Kazuyoshi Shiga, Ryo Ogawa, Yoichi Matsuo, Akira Mitsui, Masahiro Kimura, Shuji Takiguchi   +13 more
doaj   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang, Qitai Chen, YuJie Yu, Yi Zang, Rujia Zheng, Zhe Zhang, Shuaijun Lu, Li Zhou   +7 more
wiley   +1 more source

Recombination homeostasis of meiosis during spermatogenesis under nicotine treatment [PDF]

Archives of Biological Sciences, 2018
Cigarette smoking can affect male fertility via the quality of semen. To explore the effects of nicotine, a major component of cigarettes, on meiotic recombination during spermatogenesis, C57BL/6J male mice were injected with nicotine at a dosage of 0.2 ...
Zhai Jingli, Yuan Qingqing, Yang Tianqi, Zhao Xianglong, Zhang Meixing, Zhang Dong, Xu Wangjie, Qiao Zhongdong   +7 more
doaj   +1 more source

Effect of Different Extraction Methods and Geographical Origins on the Total Phenolic Yield, Composition, and Antimicrobial Activity of Sugarcane Bagasse Extracts

Frontiers in Nutrition, 2022
Several parameters, including particle size, solvent, temperature, and extraction method, affect phenolic compounds' extraction yield from a plant matrix.
Victor Velázquez-Martínez, Victor Velázquez-Martínez, Victor Velázquez-Martínez, Delia Valles-Rosales, Laura Rodríguez-Uribe, Juan Rodrigo Laguna-Camacho, Hector Daniel López-Calderón, Efren Delgado   +7 more
doaj   +1 more source

Leucine modulates the IPEC-J2 cell proteome associated with cell proliferation, metabolism and phagocytosis

Animal Nutrition, 2018
Leucine can affect intestinal protein expressions, and improve mucosal immune function. However, little study has been conducted to determine the change of protein component by leucine treatment in intestine epithelial cells.
Xiangbing Mao, Man Ren, Daiwen Chen, Bing Yu, Lianqiang Che, Jun He, Junqiu Luo, Yuheng Luo, Jianping Wang, Hui Sun   +9 more
doaj   +1 more source