Results 41 to 50 of about 88,213 (281)

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Human Mycotoxin Biomonitoring: Conclusive remarks on direct or indirect assessment of urinary deoxynivalenol [PDF]

, 2020
Deoxynivalenol is one of the most ubiquitous mycotoxins in the Western diet through its presence in cereals and cereal products. A vast amount of studies indicate the worrying level of exposure to this toxin, while even high percentages of the population
Bouzaghnane, Nabila, De Boevre, Marthe, De Saeger, Sarah, Vidal Corominas, Arnau   +3 more
core   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Dose and Exposure Time-Dependent Renal and Hepatic Effects of Intraperitoneally Administered Fumonisin B₁ in Rats

Toxins, 2018
Male Wistar rats were treated intraperitoneally (i.p.) with fumonisin B1 (FB1; 0, 20, 50 and 100 mg/kg dietary dose equivalent) for 5 and 10 days (n = 24⁻24 in each setting) to gain dose- and time-dependent effects on antioxidant status and ...
András Szabó, Judit Szabó-Fodor, Mariam Kachlek, Miklós Mézes, Krisztián Balogh, Róbert Glávits, Omeralfaroug Ali, Yarsmin Yunus Zeebone, Melinda Kovács   +8 more
doaj   +1 more source

Mycotoxins and Mycotoxin Producing Fungi in Pollen: Review [PDF]

Toxins, 2019
Due to its divergent chemical composition and good nutritional properties, pollen is not only important as a potential food supplement but also as a good substrate for the development of different microorganisms. Among such microorganisms, toxigenic fungi are extremely dangerous as they can synthesize mycotoxins as a part of their metabolic pathways ...
Aleksandar Ž. Kostić, Danijel D. Milinčić, Tanja S. Petrović, Vesna S. Krnjaja, Sladjana P. Stanojević, Miroljub B. Barać, Živoslav Lj. Tešić, Mirjana B. Pešić   +7 more
openaire   +6 more sources

Review of mycotoxin reduction in food and feed: from prevention in the field to detoxification by adsorption or transformation [PDF]

, 2011
Mycotoxins are secondary metabolites present worldwide in agricultural commodities and produced by filamentous fungi that cause a toxic response (mycotoxicosis) when ingested by animals.
Guyonvarc’h, Alain, Jard, Gwénaëlle, Lebrihi, Ahmed, Liboz, Thierry, Mathieu, Florence   +4 more
core   +4 more sources

CACLENS: A Multitask Deep Learning System for Enzyme Discovery

Advanced Science, EarlyView.
CACLENS, a multimodal and multi‐task deep learning framework integrating cross‐attention, contrastive learning, and customized gate control, enables reaction type classification, EC number prediction, and reaction feasibility assessment. CACLENS accelerates functional enzyme discovery and identifies efficient Zearalenone (ZEN)‐degrading enzymes.
Xilong Yi, Yingzhu Tan, Huikang Lin, Guoqing Zhang, Ye Tian, Aibo Wu   +5 more
wiley   +1 more source

Carcinogenic Mycotoxins*

, 2010
Mycotoxins are metabolites of molds considered to be a major risk factor affecting human and animal health. It is estimated that 25% of the world’s crop production is contaminated with mycotoxins. Mold contamination occurs extensively in fields and is particularly severe in tropical countries.
Peraica, Maja, Domijan, Ana-Marija
openaire   +2 more sources

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Modelling a two-dimensional spatial distribution of mycotoxin concentration in bulk commodities to design effective and efficient sample selection strategies [PDF]

, 2009
Mycotoxins in agricultural commodities are a hazard to human and animal health. Their heterogeneous spatial distribution in bulk storage or transport makes it particularly difficult to design effective and efficient sampling plans.
Magan, Naresh, Origgi, S., Parsons, David J., Rivas Casado, Monica, Weightman, R. M.   +4 more
core   +4 more sources