Results 21 to 30 of about 294,817 (379)
Glia, 2017 AbstractMyelinating cells surround axons to accelerate the propagation of action potentials, to support axonal health, and to refine neural circuits. Myelination is metabolically demanding and, consistent with this notion, mTORC1—a signaling hub coordinating cell metabolism—has been implicated as a key signal for myelination.
Gianluca Figlia +2 more
openaire +4 more sources
Journal of Cell Science, 2014 ABSTRACTThe myelin sheath is a plasma membrane extension that is laid down in regularly spaced segments along axons of the nervous system. This process involves extensive changes in oligodendrocyte cell shape and membrane architecture. In this Cell Science at a Glance article and accompanying poster, we provide a model of how myelin of the central ...
Snaidero, Nicolas, Simons, Mikael
openaire +4 more sources
Exogenous schwann cells migrate, remyelinate and promote clinical recovery in experimental auto-immune encephalomyelitis [PDF]
, 2012 Schwann cell (SC) transplantation is currently being discussed as a strategy that may promote functional recovery in patients with multiple sclerosis (MS) and other inflammatory demyelinating diseases of the central nervous system (CNS).
Bachelin, Corinne +9 more
core +13 more sources
Acta Neuropathologica, 2020 Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) triggered by autoimmune mechanisms.
Francesca Cignarella +19 more
semanticscholar +1 more source
Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
Nature Communications, 2020 Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear.
Najate Benamer +3 more
doaj +1 more source
An atlas for human brain myelin content throughout the adult life span
Scientific Reports, 2021 Myelin water imaging is a quantitative neuroimaging technique that provides the myelin water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular T 2 (IET2), which is related to water and iron content. We coupled high-
A. Dvorak +15 more
semanticscholar +1 more source
Orphanet Journal of Rare Diseases, 2019 Background Ribonucleases (RNases) are crucial for degradation of ribosomal RNA (rRNA). RNASET2 as a subtype of RNASEs is a 256 amino acid protein, encoded by RNASET2 gene located on chromosome six.
Reyhaneh Kameli +9 more
doaj +1 more source
Confined Multilamellae Prefer Cylindrical Morphology [PDF]
, 2005 By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: The bilayer repeat spacing increases and thus the ...
Huang, Jung-Ren +2 more
core +1 more source
Microglia phagocytose myelin sheaths to modify developmental myelination
Nature Neuroscience, 2020 During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown.
Alexandria N. Hughes, B. Appel
semanticscholar +1 more source
Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
Frontiers in Neuroscience, 2019 In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye +11 more
doaj +1 more source