Results 21 to 30 of about 300,317 (388)

Myelin plasticity: sculpting circuits in learning and memory

Nature Reviews Neuroscience, 2020
Wendy Xin, Jonah R Chan
exaly   +2 more sources

Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory

Nature Neuroscience, 2020
Bo Hu, Lan Xiao, Jonah R Chan
exaly   +2 more sources

The Metabolism of Myelin [PDF]

Proceedings of the Royal Society of Medicine, 1961
G. Payling Wright
openalex   +4 more sources

The Angiotensin II Type 2 Receptor, a Target for Protection and Regeneration of the Peripheral Nervous System?

Pharmaceuticals, 2021
Preclinical evidence, accumulated over the past decade, indicates that the angiotensin II type 2 receptor (AT2R) stimulation exerts significant neuroprotective effects in various animal models of neuronal injury, notably in the central nervous system ...
Aurore Danigo, Amandine Rovini, Flavien Bessaguet, Hichem Bouchenaki, Amandine Bernard, Franck Sturtz, Sylvie Bourthoumieu, Alexis Desmoulière, Laurent Magy, Claire Demiot   +9 more
doaj   +1 more source

Ramipril Alleviates Oxaliplatin-Induced Acute Pain Syndrome in Mice

Frontiers in Pharmacology, 2021
Oxaliplatin is a key drug for colorectal cancer that causes OXP-induced peripheral neuropathy, a dose-limiting effect characterized by cold and tactile hyperesthesia.
Hichem Bouchenaki, Aurore Danigo, Amandine Bernard, Flavien Bessaguet, Laurence Richard, Laurence Richard, Franck Sturtz, David Balayssac, Laurent Magy, Laurent Magy, Claire Demiot   +10 more
doaj   +1 more source

Myelination [PDF]

Current Biology, 2016
Myelin is a key evolutionary acquisition that underlay the development of the large, complex nervous systems of all hinged-jaw vertebrates. By promoting rapid, efficient nerve conduction, myelination also made possible the development of the large body size of these vertebrates.
Salzer, J.L., Zalc, B.
openaire   +3 more sources

Age-related myelin degradation burdens the clearance function of microglia during aging

Nature Neuroscience, 2016
Simone Brioschi, Knut Biber, Simon Yona
exaly   +2 more sources

Ceruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems

Redox Biology, 2021
Ceruloplasmin (Cp) is a ferroxidase enzyme that is essential for cell iron efflux and has been postulated to have a neuroprotective role. During the myelination process, oligodendrocytes (OLs) and Schwann cells (SCs) express high levels of Cp, but the ...
D.A. Santiago González, V.T. Cheli, S.L. Rosenblum, G. Denaroso, P.M. Paez   +4 more
doaj   +1 more source

ACER3-related leukoencephalopathy: expanding the clinical and imaging findings spectrum due to novel variants

Human Genomics, 2021
Background Leukodystrophies are the main subgroup of inherited CNS white matter disorders which cause significant mortality and morbidity in early years of life.
Ali Zare Dehnavi, Erfan Heidari, Maryam Rasulinezhad, Morteza Heidari, Mahmoud Reza Ashrafi, Mohammad Mahdi Hosseini, Fatemeh Sadeghzadeh, Mohammad-Sadegh Fallah, Noushin Rostampour, Amir Bahraini, Masoud Garshasbi, Ali Reza Tavasoli   +11 more
doaj   +1 more source

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

Nature Communications, 2022
Myelin, the electrically insulating sheath on axons, undergoes dynamic changes over time. However, it is composed of proteins with long lifetimes. This raises the question how such a stable structure is renewed. Here, we study the integrity of myelinated
M. Meschkat, A. Steyer, M. Weil, Kathrin Kusch, O. Jahn, Lars Piepkorn, Paola Agüi-Gonzalez, Nhu T. N. Phan, T. Ruhwedel, Boguslawa Sadowski, S. Rizzoli, H. Werner, H. Ehrenreich, K. Nave, W. Möbius   +14 more
semanticscholar   +1 more source