Results 21 to 30 of about 188,742 (365)
Microglia phagocytose myelin sheaths to modify developmental myelination
Nature Neuroscience, 2020 During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown.
Alexandria N. Hughes, B. Appel
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The Metabolism of Myelin [PDF]
Proceedings of the Royal Society of Medicine, 1961 G. Payling Wright
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Journal of Cell Science, 2014 ABSTRACTThe myelin sheath is a plasma membrane extension that is laid down in regularly spaced segments along axons of the nervous system. This process involves extensive changes in oligodendrocyte cell shape and membrane architecture. In this Cell Science at a Glance article and accompanying poster, we provide a model of how myelin of the central ...
Snaidero, Nicolas, Simons, Mikael
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Acta Neuropathologica, 2020 Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) triggered by autoimmune mechanisms.
Francesca Cignarella +19 more
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Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
Nature Communications, 2020 Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear.
Najate Benamer +3 more
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Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism
Cells, 2020 Myelin is critical for the proper function of the nervous system and one of the most complex cell–cell interactions of the body. Myelination allows for the rapid conduction of action potentials along axonal fibers and provides physical and trophic ...
Y. Poitelon +2 more
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Orphanet Journal of Rare Diseases, 2019 Background Ribonucleases (RNases) are crucial for degradation of ribosomal RNA (rRNA). RNASET2 as a subtype of RNASEs is a 256 amino acid protein, encoded by RNASET2 gene located on chromosome six.
Reyhaneh Kameli +9 more
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Bilateral horizontal gaze palsy in an 8‐year‐old girl: A rare case with NDUFS4 gene mutation
Clinical Case Reports, 2021 We report a patient with complex clinical presentation including multiple neurological symptoms and eye involvement. Upon genetic investigation, the patient was found to carry a novel homozygous mutation in the NDUFS4 gene, thus adding to the ...
Mohammad Vafaee‐Shahi +6 more
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Myelin in the Central Nervous System: Structure, Function, and Pathology.
Physiological Reviews, 2019 Oligodendrocytes generate multiple layers of myelin membrane around axons of the central nervous system to enable fast and efficient nerve conduction.
C. Stadelmann +3 more
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Polarization and Myelination in Myelinating Glia [PDF]
ISRN Neurology, 2012 Myelinating glia, oligodendrocytes in central nervous system and Schwann cells in peripheral nervous system, form myelin sheath, a multilayered membrane system around axons enabling salutatory nerve impulse conduction and maintaining axonal integrity.
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