Results 31 to 40 of about 188,742 (365)
Oligodendrocytes in Development, Myelin Generation and Beyond
Cells, 2019 Oligodendrocytes are the myelinating cells of the central nervous system (CNS) that are generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the CNS and represent a pool of migratory and proliferative adult progenitor ...
S. Kuhn +3 more
semanticscholar +1 more source
EMBO Molecular Medicine, 2019 Current treatments in multiple sclerosis (MS) are modulating the inflammatory component of the disease, but no drugs are currently available to repair lesions.
Fabien Binamé +12 more
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Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
Frontiers in Neuroscience, 2019 In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye +11 more
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White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes
Acta Neuropathologica Communications, 2018 Alzheimer’s disease (AD) is conceptualized as a progressive consequence of two hallmark pathological changes in grey matter: extracellular amyloid plaques and neurofibrillary tangles.
S. E. Nasrabady +3 more
semanticscholar +1 more source
Myelin activates FAK/Akt/NF-kappaB pathways and provokes CR3-dependent inflammatory response in murine system. [PDF]
PLoS ONE, 2010 Inflammatory response following central nervous system (CNS) injury contributes to progressive neuropathology and reduction in functional recovery. Axons are sensitive to mechanical injury and toxic inflammatory mediators, which may lead to demyelination.
Xin Sun +11 more
doaj +1 more source
Myelin figures: the buckling and flow of wet soap [PDF]
Phys. Rev. E 79, 061502 (2009), 2009 Myelin figures are interfacial structures formed when certain surfactants swell in excess water. Here, I present data and model calculations suggesting myelin formation and growth is due to the fluid flow of surfactant, driven by the hydration gradient at the dry surfactant/water interface; a simple model based on this idea qualitatively reproduces the
arxiv +1 more source
Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex
Nature Neuroscience, 2018 Oligodendrocyte generation in the adult CNS provides a means to adapt the properties of circuits to changes in life experience. However, little is known about the dynamics of oligodendrocytes and the extent of myelin remodeling in the mature brain. Using
Ethan G. Hughes +3 more
semanticscholar +1 more source
Effect of swimming on oligodendrocytic cells and myelin tissue in corpus callosum of rat model of MS induced by Cuprizone [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2021 Background: Multiple Sclerosis is a myelin destroyer disease, which physical activity can be effective in improving it. Therefore, in the present study, the effect of swimming on oligodendrocytic cells and myelin tissue in rat brain of the Cuprizone ...
Ebrahim Bagheri +3 more
doaj +1 more source
Theranostics, 2020 Rationale: Autophagy in Schwann cells (SCs) is crucial for myelin debris degradation and clearance following peripheral nerve injury (PNI). Nerve growth factor (NGF) plays an important role in reconstructing peripheral nerve fibers and promoting axonal ...
Rui Li +14 more
semanticscholar +1 more source
eLife, 2022 Human myelin disorders are commonly studied in mouse models. Since both clades evolutionarily diverged approximately 85 million years ago, it is critical to know to what extent the myelin protein composition has remained similar.
Vasiliki-Ilya Gargareta +12 more
doaj +1 more source