Results 91 to 100 of about 124,147 (190)

Myelin-associated proteins are potential diagnostic markers in patients with primary brain tumour

, 2021
Taking into account the possibility of myelin-associated proteins having a role in brain tumour development, the study aimed to evaluate the diagnostic usefulness of myelin-associated proteins (Nogo-A, MAG, OMgp) released into extracellular space in ...
Ewa Matuszczak (4821702), Olga M. Koper-Lenkiewicz (11602751), Mariusz W. Mucha (11602769), Karol Sawicki (11602757), Joanna Matowicka-Karna (9344574), Violetta Dymicka-Piekarska (9344568), Robert Pawlak (400743), Joanna Reszeć (9344565), Marzena Tylicka (4821696), Anna J. Milewska (11602754), Joanna Kamińska (8886032), Justyna Zińczuk (11602763), Robert Chrzanowski (11602760), Zenon Mariak (11602766)   +13 more
core   +1 more source

Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment

MedComm, Volume 7, Issue 9, September 2026.
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu, Yuan Zhang, Chen Shi, Yu Tao, Shaoxin Li, Yufang Sun, Fuhai Ji, Dongsheng Jiang, Terrance P. Snutch, Jin Tao   +9 more
wiley   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao, Jinxiu Qian, Qiqiong Liu, Wanting Ye, Ying Xing, Xiuyun Bai, Rongjun Deng, Jue Yang, Cheng Lu, Cheng Xiao, Yuanyan Liu   +10 more
wiley   +1 more source

The Host Defense Proteome of Human and Bovine Milk [PDF]

, 2011
Milk is the single source of nutrients for the newborn mammal. The composition of milk of different mammals has been adapted during evolution of the species to fulfill the needs of the offspring.
Hooijdonk, A.C.M., van, Jacques Vervoort, Boeren, S., Hein van Valenberg, van Hooijdonk, A.C.M., Vervoort Jacques, van Valenberg Hein, Sacco de Vries, de Vries Sacco, Boeren Sjef, Hettinga Kasper, Vries, S.C., de, Valenberg, H.J.F., van, Hettinga, K.A., van Hooijdonk Toon, Kasper Hettinga, Sjef Boeren, de Vries, S.C., Arendonk, J.A.M., van, Toon van Hooijdonk, Johan van Arendonk, van Arendonk, J.A.M., van Arendonk Johan, Vervoort, J.J.M., van Valenberg, H.J.F.   +24 more
core   +2 more sources

A Review of the Therapeutic Potential of Stem Cell‐Derived Nanocarriers to Treat Neurological Disorders

ChemistryOpen, Volume 15, Issue 9, September 2026.
Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor, Ahmed Abdelgader, Magdi Abobaker, Yahya E. Choonara   +3 more
wiley   +1 more source

The septin cytoskeleton is associated with distinct myelin structures of the central and peripheral nervous system [PDF]

, 2008
Rapid conduction of nerve impulses in the nervous system of higher vertebrates is made possible by ensheathment of nerve fibers by the specialized plasma membrane structure myelin. Consequently, failure of myelination or damage to the myelin sheath leads
Buser, Andres
core   +1 more source

Proteomic prediction of myelin water fraction using the SomaScan 7k platform

Alzheimer's & Dementia
AbstractBackgroundMyelin loss occurs as part of neurodegenerative and neuroinflammatory conditions. Myelin water fraction (MWF), a surrogate of myelin content, can be estimated using multicomponent relaxometry MRI. In this study we investigate the relationship between 7289 plasma proteins and MWF to derive a protein‐based indicator of myelin content ...
Joynes, Cassandra M, Resnick, Susan M., Bouhrara, Mustapha, Walker, Keenan A.   +3 more
openaire   +1 more source

Target Proteins in the Dorsal Hippocampal Formation Sustain the Memory-Enhancing and Neuroprotective Effects of Ginkgo biloba

Frontiers in Pharmacology, 2019
We have previously shown that standardized extracts of Ginkgo biloba (EGb) modulate fear memory formation, which is associated with CREB-1 (mRNA and protein) upregulation in the dorsal hippocampal formation (dHF), in a dose-dependent manner.
Renan Barretta Gaiardo, Thiago Ferreira Abreu, Alexandre Keiji Tashima, Monica Marques Telles, Suzete Maria Cerutti   +4 more
doaj   +1 more source

Hypothalamic protein profiling from mice subjected to social defeat stress

Molecular Brain
The Hypothalmic-Pituitary-Adrenal axis also known as the HPA axis is central to stress response. It also acts as the relay center between the body and the brain.
Shiladitya Mitra, Ghantasala S. Sameer Kumar, Anumita Samanta, Mathias V. Schmidt, Suman S. Thakur   +4 more
doaj   +1 more source

Combined transcriptomic and proteomic analyses reveal relevant myelin features in mice with ischemic stroke

Functional & Integrative Genomics
Ischemic stroke (IS), a leading cause of global disability and mortality, is characterized by white matter damage and demyelination. Despite advances, the molecular mechanisms driving post-IS myelin pathology remain poorly understood, limiting therapeutic development. This study investigates key myelin-related genes (MRGs) and their regulatory networks
Qiuyang Qian, Hao Lyu, Wei Wang, Qiwen Wang, Desheng Li, Xiaojia Liu, Yi He, Mei Shen   +7 more
openaire   +2 more sources