Results 11 to 20 of about 13,038 (207)
Proteomic analysis of peripheral nerve myelin during murine aging
Frontiers in Cellular Neuroscience, 2023 Aging of the peripheral nervous system (PNS) is associated with structural and functional changes that lead to a reduction in regenerative capacity and the development of age-related peripheral neuropathy.
Dario Lucas Helbing +13 more
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Quantitative and Integrative Proteome Analysis of Peripheral Nerve Myelin Identifies Novel Myelin Proteins and Candidate Neuropathy Loci [PDF]
The Journal of Neuroscience, 2011 Peripheral nerve myelin facilitates rapid impulse conduction and normal motor and sensory functions. Many aspects of myelin biogenesis, glia–axonal interactions, and nerve homeostasis are poorly understood at the molecular level. We therefore hypothesized that only a fraction of all relevant myelin proteins has been identified so far.
Julia Patzig +16 more
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An overview of the human brain myelin proteome and differences associated with schizophrenia
The World Journal of Biological Psychiatry, 2020 Disturbances in the myelin sheath drive disruptions in neural transmission and brain connectivity as seen in schizophrenia. Here, the myelin proteome was characterised in schizophrenia patients and healthy controls to visualise differences in proteomic profiles.A liquid chromatography tandem mass spectrometry-based shotgun proteomic analysis was ...
Daniel Martins‐de‐Souza +5 more
+7 more sources
Author response: Proteome profile of peripheral myelin in healthy mice and in a neuropathy model
, 2019 Sophie B. Siems +13 more
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Decision letter: Proteome profile of peripheral myelin in healthy mice and in a neuropathy model
, 2019 openalex +2 more sources
Mitochondria in Myelinating Oligodendrocytes: Slow and Out of Breath?
Metabolites, 2021 Myelin is a lipid-rich membrane that wraps around axons and facilitates rapid action potential propagation. In the brain, myelin is synthesized and maintained by oligodendrocytes.
Niklas Meyer, Johanne Egge Rinholm
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Myelin Proteomics: Molecular Anatomy of an Insulating Sheath [PDF]
Molecular Neurobiology, 2009 Fast-transmitting vertebrate axons are electrically insulated with multiple layers of nonconductive plasma membrane of glial cell origin, termed myelin. The myelin membrane is dominated by lipids, and its protein composition has historically been viewed to be of very low complexity.
Jahn, O., Tenzer, S., Werner, H.
openaire +4 more sources