Results 31 to 40 of about 132,321 (210)

Global profiling of the proteome, phosphoproteome, and N-glycoproteome of protoscoleces and adult worms of Echinococcus granulosus

Frontiers in Veterinary Science, 2023
IntroductionCystic echinococcosis (CE) is a chronic zoonosis caused by infection with the metacestode of the Echinococcus granulosus. A unique characteristic of E.
Zhengrong Wang, Zhengrong Wang, Xinyue Jia, Xinyue Jia, Xinyue Jia, Jing Ma, Jing Ma, Jing Ma, Yanyan Zhang, Yanyan Zhang, Yan Sun, Yan Sun, Xinwen Bo, Xinwen Bo, Xinwen Bo   +14 more
doaj   +1 more source

Functional role of the overexpression of the myelin and lymphocyte protein MAL in Schwann cells [PDF]

, 2013
For fast propagation of action potentials in the nervous system, higher vertebrates have developed a specialized plasma membrane structure, the myelin, ensheathing nerve fibers. Myelin sheaths are formed by Schwann cells in the peripheral nervous system (
Schmid, Daniela
core   +1 more source

Proteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease

World Journal of Pediatrics, 2022
Abstract Background Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder of the central nervous system. Methods Extracted proteins from 34 cerebrospinal fluid (CSF) samples [patients with MOGAD (MOG group, n ...
Wang, Yi-Long, Zhu, Meng-Ying, Yuan, Zhe-Feng, Ren, Xiao-Yan, Guo, Xiao-Tong, Hua, Yi, Xu, Lu, Zhao, Cong-Ying, Jiang, Li-Hua, Zhang, Xin, Sheng, Guo-Xia, Jiang, Pei-Fang, Zhao, Zheng-Yan, Gao, Feng   +13 more
openaire   +2 more sources

Protein expression profiling in rat hippocampus after focal cerebral ischemia injury [PDF]

Journal of Integrative Neuroscience, 2018
The aim in this study was to explore protein expression profiles in the rat hippocampus after induction of focal ischemia injury. Forty male Sprague Dawley rats were randomly divided into four equal groups after ischemia injury surgery: Control, Day 3 ...
Lichan He, Rui He, Ruihua Liang, Yi Li, Xiaoqiang Li, Chuqiao Li, Suping Zhang
doaj   +1 more source

Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function

Cells, 2023
Thyroid hormone (TH) transporter MCT8 deficiency causes severe locomotor disabilities likely due to insufficient TH transport across brain barriers and, consequently, compromised neural TH action.
Devon Siemes, Pieter Vancamp, Boyka Markova, Philippa Spangenberg, Olga Shevchuk, Bente Siebels, Hartmut Schlüter, Steffen Mayerl, Heike Heuer, Daniel Robert Engel   +9 more
doaj   +1 more source

The transcriptome of mouse central nervous system myelin [PDF]

, 2016
Rapid nerve conduction in the CNS is facilitated by insulation of axons with myelin, a specialized oligodendroglial compartment distant from the cell body.
Garding, Angela, Garding, A., Jung, Ramona B., Goebbels, S., White, Robin, Goebbels, Sandra, Werner, H., Tiwari, Vijay K., Jung, R., Thakurela, S., Müller, C., Müller, Christina, Tiwari, V., Thakurela, Sudhir, Werner, Hauke B., White, R.   +15 more
core   +1 more source

Synthesis of antagonists of Myelin-associated glycoprotein (MAG) for conformational and SAR studies [PDF]

, 2004
Damage to the central nervous system (CNS) of higher vertebrates, including humans, often results in devastating and persistent functional deficits.
Gao, Gan-Pan
core   +1 more source

Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease

Acta Neuropathologica Communications, 2018
Although the genetic causes for several rare, familial forms of Alzheimer’s disease (AD) have been identified, the etiology of the sporadic form of AD remains unclear.
Qi Zhang, Cheng Ma, Marla Gearing, Peng George Wang, Lih-Shen Chin, Lian Li   +5 more
doaj   +1 more source

Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

Frontiers in Immunology, 2020
Background: MiR-146a is an important regulator of innate inflammatory responses and is also implicated in cell death and survival.Methods: By sorting CNS resident cells, microglia were the main cellular source of miR-146a.
Nellie A. Martin, Kirsten H. Hyrlov, Maria L. Elkjaer, Eva K. Thygesen, Agnieszka Wlodarczyk, Agnieszka Wlodarczyk, Kirstine J. Elbaek, Christopher Aboo, Christopher Aboo, Justyna Okarmus, Eirikur Benedikz, Richard Reynolds, Zoltan Hegedus, Zoltan Hegedus, Allan Stensballe, Åsa Fex Svenningsen, Trevor Owens, Trevor Owens, Zsolt Illes, Zsolt Illes, Zsolt Illes   +20 more
doaj   +1 more source

Flexible Integration of Structurally Diverse Spatial Multi‐Omics With AgaeSMO [PDF]

Advanced science
AgaeSMO is a versatile and robust deep learning framework for flexible cross‐integration of spatial multi‐omics data. Leveraging a GATs network with a graph attention module, it learns joint embedding across diverse modalities, enabling integration of both structurally paired (e.g., spatial transcriptome‐epigenome, transcriptome‐proteome, transcriptome‐
Liu K, Su J, Zhou H, Shen Y, Qin M, Luo Y, Wang T, Chen Z, Wang Y, Ma X.   +9 more
europepmc   +2 more sources