Results 31 to 40 of about 124,147 (190)

Membrane Protein Identification in Rodent Brain Tissue Samples and Acute Brain Slices

Cells, 2019
Acute brain slices are a sample format for electrophysiology, disease modeling, and organotypic cultures. Proteome analyses based on mass spectrometric measurements are seldom used on acute slices, although they offer high-content protein analyses and ...
Sarah Joost, Stefan Mikkat, Michael Wille, Antje Schümann, Oliver Schmitt   +4 more
doaj   +1 more source

Global profiling of the proteome, phosphoproteome, and N-glycoproteome of protoscoleces and adult worms of Echinococcus granulosus

Frontiers in Veterinary Science, 2023
IntroductionCystic echinococcosis (CE) is a chronic zoonosis caused by infection with the metacestode of the Echinococcus granulosus. A unique characteristic of E.
Zhengrong Wang, Zhengrong Wang, Xinyue Jia, Xinyue Jia, Xinyue Jia, Jing Ma, Jing Ma, Jing Ma, Yanyan Zhang, Yanyan Zhang, Yan Sun, Yan Sun, Xinwen Bo, Xinwen Bo, Xinwen Bo   +14 more
doaj   +1 more source

Proteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease

World Journal of Pediatrics, 2022
Abstract Background Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder of the central nervous system. Methods Extracted proteins from 34 cerebrospinal fluid (CSF) samples [patients with MOGAD (MOG group, n ...
Wang, Yi-Long, Zhu, Meng-Ying, Yuan, Zhe-Feng, Ren, Xiao-Yan, Guo, Xiao-Tong, Hua, Yi, Xu, Lu, Zhao, Cong-Ying, Jiang, Li-Hua, Zhang, Xin, Sheng, Guo-Xia, Jiang, Pei-Fang, Zhao, Zheng-Yan, Gao, Feng   +13 more
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Protein expression profiling in rat hippocampus after focal cerebral ischemia injury [PDF]

Journal of Integrative Neuroscience, 2018
The aim in this study was to explore protein expression profiles in the rat hippocampus after induction of focal ischemia injury. Forty male Sprague Dawley rats were randomly divided into four equal groups after ischemia injury surgery: Control, Day 3 ...
Lichan He, Rui He, Ruihua Liang, Yi Li, Xiaoqiang Li, Chuqiao Li, Suping Zhang
doaj   +1 more source

Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function

Cells, 2023
Thyroid hormone (TH) transporter MCT8 deficiency causes severe locomotor disabilities likely due to insufficient TH transport across brain barriers and, consequently, compromised neural TH action.
Devon Siemes, Pieter Vancamp, Boyka Markova, Philippa Spangenberg, Olga Shevchuk, Bente Siebels, Hartmut Schlüter, Steffen Mayerl, Heike Heuer, Daniel Robert Engel   +9 more
doaj   +1 more source

The evolution of the plant organellar proteome [PDF]

, 2022
A hallmark of eukaryotic cells is the compartmentalisation of intracellular processes into specialised, membrane-bound compartments known as organelles. The function of organelles is dependent on a suite of proteins localised within them (the organellar ...
Costello, Rona Moira Oonagh
core   +1 more source

Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease

Acta Neuropathologica Communications, 2018
Although the genetic causes for several rare, familial forms of Alzheimer’s disease (AD) have been identified, the etiology of the sporadic form of AD remains unclear.
Qi Zhang, Cheng Ma, Marla Gearing, Peng George Wang, Lih-Shen Chin, Lian Li   +5 more
doaj   +1 more source

Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

Frontiers in Immunology, 2020
Background: MiR-146a is an important regulator of innate inflammatory responses and is also implicated in cell death and survival.Methods: By sorting CNS resident cells, microglia were the main cellular source of miR-146a.
Nellie A. Martin, Kirsten H. Hyrlov, Maria L. Elkjaer, Eva K. Thygesen, Agnieszka Wlodarczyk, Agnieszka Wlodarczyk, Kirstine J. Elbaek, Christopher Aboo, Christopher Aboo, Justyna Okarmus, Eirikur Benedikz, Richard Reynolds, Zoltan Hegedus, Zoltan Hegedus, Allan Stensballe, Åsa Fex Svenningsen, Trevor Owens, Trevor Owens, Zsolt Illes, Zsolt Illes, Zsolt Illes   +20 more
doaj   +1 more source

Proteomic analysis of nuclear factors binding to an intronic enhancer in the myelin proteolipid protein gene [PDF]

Journal of Neurochemistry, 2008
AbstractThe myelin proteolipid protein gene (Plp1) encodes the most abundant protein found in CNS myelin, accounting for nearly one‐half of the total protein. Its expression in oligodendrocytes is developmentally regulated – peaking during the active myelination period of CNS development. Previously, we have identified a novel enhancer (designated ASE)
Anna, Dobretsova, Jennifer W, Johnson, Richard C, Jones, Ricky D, Edmondson, Patricia A, Wight   +4 more
openaire   +2 more sources

A Nanoscale Model System for the Human Myelin Sheath [PDF]

, 2021
Here, we for the first time establish nanodiscs with the challenging lipid composition of myelin of the peripheral or central nervous systems, respectively (PNS and CNS, both containing >40% cholesterol, which so far has been thought to be detrimental ...
David, Haselberger, Carla, Schmidt, Tommy, Hofmann, Annette, Meister, Panagiotis L., Kastritis, Lisa, Müller, Kevin, Janson, Carolyn, Vargas, Matthias, Hoffmann, Sandro, Keller, Dariush, Hinderberger, manabendra, das   +11 more
core   +2 more sources