Results 11 to 20 of about 108,757 (334)
Prolonged Environmental Enrichment Promotes Developmental Myelination
Frontiers in Cell and Developmental Biology, 2021 Postnatal neurodevelopment is profoundly influenced by environmental experiences. Environmental enrichment is a commonly used experimental paradigm that has uncovered numerous examples of experience-dependent plasticity in health and disease.
Evan Z. Goldstein +4 more
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A Glance at the Molecules That Regulate Oligodendrocyte Myelination
Current Issues in Molecular Biology, 2022 Oligodendrocyte (OL) myelination is a critical process for the neuronal axon function in the central nervous system. After demyelination occurs because of pathophysiology, remyelination makes repairs similar to myelination.
Shunqi Wang, Yingxing Wang, Suqi Zou
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Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination. [PDF]
PLoS ONE, 2013 The timing and progression of axonal myelination are precisely controlled by intercellular interactions between neurons and glia in development. Previous in vitro studies demonstrated that Nectin like 4 (Necl-4, also known as cell adhesion molecule Cadm ...
Ying Zhu +12 more
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Frontiers in Neuroscience, 2022 The development of neuronal circuitry required for cognition, complex motor behaviors, and sensory integration requires myelination. The role of glial cells such as astrocytes and microglia in shaping synapses and circuits have been covered in other ...
Daniela M. S. Moura +4 more
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Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]
, 2017 Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H. +5 more
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Neuron–Oligodendrocyte Communication in Myelination of Cortical GABAergic Cells
Life, 2021 Axonal myelination by oligodendrocytes increases the speed and reliability of action potential propagation, and so plays a pivotal role in cortical information processing.
Elisa Mazuir +2 more
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Myelination: all about Rac n roll. [PDF]
, 2007 During the development of the peripheral nervous system, Schwann cells select individual axons from a nerve bundle and establish a one-to-one relationship through a process termed radial sorting. Recent findings identify the Rho family GTPase Rac1 as the
Chan, Jonah
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Bihemispheric alterations in myelination in children following unilateral perinatal stroke
NeuroImage: Clinical, 2018 Background: Stroke is a leading cause of perinatal brain injury with variable outcomes including cerebral palsy and epilepsy. The biological processes that underlie these heterogeneous outcomes are poorly understood.
Sabrina Yu +7 more
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Overview of myelin, major myelin lipids, and myelin-associated proteins
Frontiers in Chemistry, 2023 Myelin is a modified cell membrane that forms a multilayer sheath around the axon. It retains the main characteristics of biological membranes, such as lipid bilayer, but differs from them in several important respects. In this review, we focus on aspects of myelin composition that are peculiar to this structure and differentiate it from the more ...
Alexander Kister, Ilya Kister
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Complement factor B is essential for the proper function of the peripheral auditory system
Frontiers in Neurology, 2023 Sensorineural hearing loss is associated with dysfunction of cochlear cells. Although immune cells play a critical role in maintaining the inner ear microenvironment, the precise immune-related molecular mechanisms underlying the pathophysiology of ...
LaShardai N. Brown +6 more
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