Results 31 to 40 of about 7,352,857 (294)
History of myeloid-derived suppressor cells [PDF]
Nature Reviews Cancer, 2013 Tumour-induced granulocytic hyperplasia is associated with tumour vasculogenesis and escape from immunity via T cell suppression. Initially, these myeloid cells were identified as granulocytes or monocytes; however, recent studies have revealed that this hyperplasia is associated with populations of multipotent progenitor cells that have been ...
James E, Talmadge, Dmitry I, Gabrilovich
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Journal of Cancer Research and Therapeutics, 2021 Context: Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immune cells of myeloid lineage. Recent reports have suggested that human MDSC are divided into three subsets: monocytic MDSC (M-MDSC), granulocytic MDSC (G-MDSC), and immature MDSC (I-MDSC). However, the characteristics of each human MDSC subset
Yoshiaki, Nagatani +7 more
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Characteristics of “Tip-DCs and MDSCs” and their potential role in leishmaniasis [PDF]
, 2012 Since the first description of dendritic cells (DCs) by Steinman and Cohn (1973), the myeloid lineage of leukocytes was investigated intensively. Nowadays it is obvious that myeloid cells, especially DCs, are crucial for the adaptive and innate immune ...
Schmid, Maximilian +8 more
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Regulatory immune cells in transplantation. [PDF]
, 2012 Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew +5 more
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Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function [PDF]
, 2010 Acute-phase proteins (APPs) are an evolutionarily conserved family of proteins produced mainly in the liver in response to infection and inflammation.
Beraza, N. +32 more
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Myeloid derived suppressor cells and autoimmunity [PDF]
Human Immunology, 2016 Myeloid-derived suppressor cells are a heterogeneous group of immature myeloid cells with immunoregulatory function. When activated and expanded, these cells can suppress T cell functions via cell-to cell interactions as well as soluble mediators. Recent studies investigated the involvement of MDSC in autoimmune diseases.
Peter, Boros +2 more
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Myeloid-derived suppressor cells and their role in gynecological malignancies
Tumor Biology, 2018 Myeloid-derived suppressor cells are a heterogeneous population of immature myeloid cells that exhibit immunosuppressive activity (they block the proliferation and activity of both T cells and natural killer cells).
Seiji Mabuchi +3 more
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Myeloid-derived suppressor cells and pulmonary hypertension
Frontiers in Immunology, 2023 Pulmonary hypertension (PH) is a chronic pulmonary vascular disorder characterized by an increase in pulmonary vascular resistance and pulmonary arterial pressure. The detailed molecular mechanisms remain unclear.
Hui Zhang +26 more
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Landscape of Myeloid-derived Suppressor Cell in Tumor Immunotherapy
Biomarker Research, 2021 Myeloid-derived suppressor cells (MDSC) are a group of immature cells that produced by emergency myelopoiesis. Emerging evidences have identified the vital role of MDSC in cancer microenvironment, in which MDSC exerts both immunological and non ...
Zhaonian Hao +5 more
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In Brief: Myeloid‐derived suppressor cells in cancer [PDF]
The Journal of Pathology, 2017 AbstractThe role of myeloid‐derived suppressor cells (MDSCs) in cancer development has become clear over recent years, and MDSC targeting is an emerging opportunity for enhancing the effectiveness of current anticancer therapies. As MDSCs are not only able to limit anti‐tumour T‐cell responses, but also to promote tumour angiogenesis and invasion ...
SOLITO, SAMANTHA +2 more
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