Results 11 to 20 of about 160,066 (290)

Expression of myeloid differentiation factor 88 in neurons is not requisite for the induction of sickness behavior by interleukin-1β [PDF]

Journal of Neuroinflammation, 2012
Background Animals respond to inflammation by suppressing normal high-energy activities, including feeding and locomotion, in favor of diverting resources to the immune response.
Braun Theodore P, Grossberg Aaron J, Veleva-Rotse Biliana O, Maxson Julia E, Szumowski Marek, Barnes Anthony P, Marks Daniel L   +6 more
doaj   +5 more sources

Identification and characterization of the myeloid differentiation factor 88 gene in yellow catfish. [PDF]

3 Biotech, 2018
Myeloid differentiation factor 88 (MyD88) is an important adapter protein of the innate immune system, but it has never before been reported in yellow catfish (Pelteobagrus fulvidraco). In this study, we cloned and characterized the yellow catfish MyD88 gene.
Yu L, Zhang L, Yang H, Gui G, Liu Y, Xiao Y.   +5 more
europepmc   +4 more sources

Circular RNA_0001187 participates in the regulation of ulcerative colitis development via upregulating myeloid differentiation factor 88. [PDF]

Bioengineered, 2022
Circular RNA (circRNA) had been confirmed to participate in ulcerative colitis (UC) development. Circular RNA_0001187 (Circ_0001187) had been found to be overexpressed in patients with Crohn disease. Therefore, circ_0001187 might be an important circRNA regulating intestinal inflammatory diseases.
Ouyang W, Wu M, Wu A, Xiao H.
europepmc   +3 more sources

An analysis of the expression and function of myeloid differentiation factor 88 in human osteosarcoma. [PDF]

Oncol Lett, 2018
The aim of the present study was to investigate the expression and function of myeloid differentiation factor 88 (MyD88) in osteosarcoma. Immunohistochemical staining was used to detect MyD88 protein in osteosarcoma tissues and matched normal bone tissues.
Chen J, He J, Yang Y, Jiang J.
europepmc   +4 more sources

Role of myeloid differentiation factor 88 in Rhesus rotavirus-induced biliary atresia. [PDF]

J Surg Res, 2013
Biliary atresia (BA) is a unique neonatal disease resulting from inflammatory and fibrosing obstruction of the extrahepatic biliary tree. Previous studies have demonstrated the critical role of innate immunity and the Th1 response to activated inflammatory cells and overexpressed cytokines in the pathogenesis of BA.
Walther AE, Mohanty SK, Donnelly B, Coots A, McNeal M, Tiao GM.   +5 more
europepmc   +4 more sources

Effects of the co-administration of morphine and lipopolysaccharide on toll-like receptor-4/nuclear factor kappa β signaling pathway of MDA-MB-231 breast cancer cells

Advanced Biomedical Research, 2023
Background: The Toll-like receptor 4 (TLR4) gene promotes migration in adenocarcinoma cells. Morphine is an agonist for TLR4 that has a dual role in cancer development.
Marzieh Kafami, Golnaz Vaseghi, Shaghayegh Haghjooy Javanmard, Manijeh Mahdavi, Nasim Dana, Nazgol Esmalian-Afyouni, Ali Gohari   +6 more
doaj   +1 more source

Myeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis. [PDF]

Infect Immun, 2018
ABSTRACTRodents are a natural host for the dimorphic pathogenic fungiCoccidioides immitisandCoccidioides posadasii, and mice are a good model for human infection. Humans and rodents both express Dectin-1 and Toll-like receptor 2 (TLR2) on myeloid cells, and those receptors collaborate to maximize the cytokine/chemokine responses to spherules (the ...
Viriyakosol S, Walls L, Okamoto S, Raz E, Williams DL, Fierer J.   +5 more
europepmc   +5 more sources

Inhibition of Mogroside IIIE on isoproterenol-induced myocardial fibrosis through the TLR4/MyD88/NF-κB signaling pathway [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): To investigate the effect of mogroside IIIE (MGIIIE) on isoproterenol (ISO)-induced myocardial fibrosis and explore its possible mechanisms.Materials and Methods: Forty C57BL/6 male mice (6-8 weeks) were randomly divided into a control ...
Yanan Shi, Bohan Li, Shuaifeng Sun, Tian Wendan, Zizhe Ma, Wei Liu   +5 more
doaj   +1 more source

Fisetin Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Targeting Myeloid Differentiation Factor 88. [PDF]

Inflammation
Acute lung injury (ALI), a severe respiratory syndrome driven by dysregulated inflammatory cascades, urgently requires novel therapeutic strategies. The activation of the MyD88 (Myeloid differentiation factor 88)-mediated TLR (Toll-like receptor) inflammatory signaling pathway plays a crucial role in the pathophysiology of ALI, while minimally ...
Jin Z, Liu X, Xie Z, Xie Y, Xu K, Zhao S, Zhou Z, Qian C, Jiang Y, Lin F, Liu Y, Chen R, Chen G, Wang Y.   +13 more
europepmc   +4 more sources

Critical role of myeloid differentiation factor 88 in necrotizing enterocolitis [PDF]

Pediatric Research, 2014
The importance of toll-like receptor 4 in necrotizing enterocolitis (NEC) has been intensively studied, but its downstream signaling and the potential regulatory mechanisms remain unidentified. Our study focused on the role of myeloid differentiation factor 88 (MyD88), the first downstream adaptor of toll-like receptor 4 inflammatory and apoptotic ...
Guozhu, Yang, Pingqian, Bao, Lie, Zhang, Zhaoying, Lyu, Bin, Zhou, Keling, Chen, Su, Peng, Yi, Wang, Longpei, Yao, Yin, Zhou, Yuan, Li   +10 more
openaire   +2 more sources