Results 21 to 30 of about 160,066 (290)
Myeloid Differentiation Factor 88 Is Required for Cross-Priming In Vivo [PDF]
The Journal of Immunology, 2004 Abstract We describe a role for myeloid differentiation factor 88 (MyD88) in the induction of functional CTLs in vivo, in response to exogenously administered Ag, using a heat shock fusion protein, hsp65-P1, as a model Ag. CD8 T cells transferred into MyD88-deficient animals produce normal numbers of CD8 effector cells that have normal ...
Deborah, Palliser +2 more
openaire +2 more sources
Journal of Ovarian Research, 2022 Objective Women with an elevated basal FSH indicate diminished ovarian reserve and reduced oocyte and embryo numbers. DMSCs are likely to be involved in immune tolerance of pregnancy maintenance. We investigate the effect of follicle-stimulating hormones
Yi-bo He +6 more
doaj +1 more source
Possible Involvement of MyD88 in Regulating Stress Response in Mice
Frontiers in Neuroscience, 2021 Myeloid differentiation primary response 88 (MyD88) is an adapter protein of the toll-like receptor (TLR) family that regulates innate immune function. Here, we identified a novel role of MyD88 in regulating stress response.
Toru Hosoi +5 more
doaj +1 more source
Dihydroartemisinin reduces lung injury in rats with hemorrhagic shock [PDF]
Jichu yixue yu linchuang, 2021 Objective To study the protective effect of dihydroartemisinin (DHA) on lung injury in rats with hemorrhagic shock (HS). Methods The rats were divided into sham operation group, model group (the left common carotid artery was treated by blood ...
YANG Ning, WANG Da-wei, ZHAO Ya-bin, CHANG Dong-ge, HE Ying-ying
doaj
The role of myeloid differentiation factor 88 on mitochondrial dysfunction of peritoneal leukocytes during polymicrobial sepsis. [PDF]
Cent Eur J Immunol, 2016 <b>Objective: </b> To investigate the role of myeloid differentiation factor 88 (MyD88) on mitochondrial dysfunction of peritoneal leukocytes during polymicrobial sepsis. <br /> <b>Material and methods: </b>Polymicrobial peritonitis, a clinically relevant mouse model of sepsis, was generated by cecum ligation and puncture (
Gong Y, Zou L, Chen D, Chao W.
europepmc +4 more sources
Myeloid differentiation factor 88 is required for resistance toNeospora caninuminfection [PDF]
Veterinary Research, 2009 Neospora caninum is an intracellular parasite that causes major economic impact on cattle raising farms, and infects a wide range of warm-blooded hosts worldwide. Innate immune mechanisms that lead to protection against this parasite are still unknown. In order to investigate whether myeloid differentiation factor 88 (MyD88) is required for resistance ...
Mineo, Tiago W.P. +3 more
openaire +3 more sources
FEBS Open Bio, 2021 Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory disease of the airway that represents a large global disease burden. Inflammation is a prominent feature of COPD and represents an important target for treatment.
Xiaoli Zeng, Xiaoju Liu, Hairong Bao
doaj +1 more source
Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML [PDF]
, 2002 HTIF1α, a transcription coactivator which is able to mediate RARα activity and functionally interact with PML, is encoded by a gene on chromosome 7q32–34, which is a critical region in acute myeloid leukemias (AML). With the assumption that this gene may
AGUIARI, Gianluca +8 more
core +1 more source
Myeloid Differentiation Factor 88 Promotes Growth and Metastasis of Human Hepatocellular Carcinoma [PDF]
Clinical Cancer Research, 2013 Abstract Purpose: To investigate the expression of myeloid differentiation factor 88 (MyD88) in hepatocellular carcinoma (HCC) and its prognostic value in patients with HCC. Experimental Design: Expression of MyD88 was detected by immunohistochemistry in surgical HCC specimens (n = 110).
Beibei, Liang +11 more
openaire +2 more sources
Beyond the immune suppression: the immunotherapy in prostate cancer [PDF]
, 2015 Prostate cancer (PCa) is the second most common cancer in men.Aswell in many other human cancers, inflammation and immune suppression have an important role in their development.We briefly describe the host components that interact with the tumor to ...
Agliano', Anna Maria +4 more
core +3 more sources