Heliyon, 2023 Long-term consumption of Arctium lappa L. roots can lead to weight loss. To explore the relationship between anti-obesity and anti-inflammation, the effects and mechanism of A. lappa L.
Feng Zeng +6 more
doaj +1 more source
The role of myeloid differentiation factor 88 on mitochondrial dysfunction of peritoneal leukocytes during polymicrobial sepsis. [PDF]
Cent Eur J Immunol, 2016 Objective: To investigate the role of myeloid differentiation factor 88 (MyD88) on mitochondrial dysfunction of peritoneal leukocytes during polymicrobial sepsis. Material and methods Polymicrobial peritonitis, a clinically relevant mouse model of sepsis,
Gong Y, Zou L, Chen D, Chao W.
europepmc +2 more sources
MyD88 Mediates Colitis- and RANKL-Induced Microfold Cell Differentiation
Veterinary Sciences, 2021 Intestinal microfold (M) cells are critical for sampling antigens in the gut and initiating the intestinal mucosal immune response. In this study, we found that the oral administration of dextran sulfate sodium (DSS) and Salmonella infection induced ...
Yang Li +8 more
doaj +1 more source
Proteomic Identification of the MYST Domain Histone Acetyltransferase TIP60 as a Coactivator of the Myeloid Transcription Factor C/EBPα [PDF]
, 2007 The transcription factor C/EBPα is a key player in granulopoiesis and leukemogenesis. In the present study, we sought to identify C/EBPα interacting proteins.
Bararia, Deepak
core +1 more source
Anti-inflammatory activity
Siliao yanjiu, 2021 The purpose of the experiment was to use lipopolysaccharide (LPS) in vitro to induce mouse peritoneal macrophages to establish an inflammation model, and to explore the in vitro anti-inflammatory activity of capsaicin. 150 8-week-old SPF Balb/c mice were
Kang-bo ZHAO +6 more
doaj
Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer's disease-related symptoms and pathology [PDF]
, 2010 Contains fulltext : 98130.pdf (Publisher’s version ) (Open Access)Alzheimer's disease is characterized by extracellular deposits of amyloid beta peptide in the brain.
Marcus O. Grimm +21 more
core +1 more source
Signaling through CD44 affects cell cycle progression and c-Jun expression in acute myeloid leukemia cells [PDF]
, 2004 We present here the first evidence linking CD44 signaling to c-Jun expression and cell cycle progression in myeloid cell line models. CD44 ligation with the anti-CD44 monoclonal antibodies have been shown to induce differentiation and inhibit the ...
Peer Zada, Abdul Ali
core +1 more source
Hexa-acylated LPS-lipid A deploys the appropriate level of fibrin to confer protection through MyD88
International Journal of Infectious Diseases, 2015 Objectives: Fibrin has been demonstrated to function protectively against pathogens in our previous studies, but we observed that a very high level of fibrin played a negative role during infection. We performed this research to address the complication.
Qi Zhao +4 more
doaj +1 more source
Antioxidants, 2022 Acute kidney injury (AKI) is described as the abrupt decrease in kidney function always accompanied by inflammation. The roots of Oxybaphus himalaicus Edgew. have long been used in Tibetan folk medicine for the treatment of nephritis.
Honghong Zhan +8 more
doaj +1 more source
Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells [PDF]
, 2011 Stem cell factor (SCF) is a hematopoietic growth factor that exerts its activity by signalling through the tyrosine kinase receptor known as Kit or CD117.
Bernhard F. Gibbs +11 more
core +2 more sources