Results 91 to 100 of about 34,282 (300)

Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in Cardiomyocytes [PDF]

, 2015
Spatio-temporal dynamics of intracellular calcium, [Ca2+]i, regulate the contractile function of cardiac muscle cells. Measuring [Ca2+]i flux is central to the study of mechanisms that underlie both normal cardiac function and calcium-dependent ...
A Baddeley, A Hatano, A Hatano, A Zahradnikova, AM Katz, Amorita Petzer, Anthony Hickey, AT Roe, AW Trafford, B Sportisse, BD Ripley, C Bradley, C Pinali, C Pinali, C Soeller, C Soeller, C Soeller, C Soeller, Cameron G. Walker, Christian Soeller, D Baddeley, D Baddeley, D Eisner, Daniel A Beard, David J. Crossman, DJ Greensmith, DM Bers, DM Bers, DR Laver, E Picht, E Theakston, EA Sobie, Edmund J. Crampin, F Brette, F Brette, F Legros, FR Heinzel, GD Smith, Gregory Bass, GSB Williams, GSB Williams, H Si, ID Jayasinghe, ID Jayasinghe, ID Jayasinghe, II Dorn, Ivo Siekmann, J Hake, J Hake, J Illian, J Moller, J Okada, JR Kremer, K Gusev, L Biesmans, L Boyman, L Zhang, LS Song, LS Song, LT Izu, M Vendelin, Mark H. Ellisman, Masahiko Hoshijima, MB Cannell, MD Stern, MD Stern, MH Ellisman, PC Bressloff, PM Kekenes-Huskey, R Turner, S Svensson, S-Q Wang, T Das, T Hayashi, T Hong, V Piacentino, Vijay Rajagopal, WE Louch, X Lu, Y Cheng, Y Hou   +80 more
core   +6 more sources

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

Alterations in thin filament length during postnatal skeletal muscle development and aging in mice

Frontiers in Physiology, 2014
The lengths of the sarcomeric thin filaments vary in a skeletal muscle-specific manner and help specify the physiological properties of skeletal muscle.
David S Gokhin, Emily A Dubuc, Kendra Q Lian, Luanne L Peters, Velia M Fowler   +4 more
doaj   +1 more source

Gill transcriptome response to changes in environmental calcium in the green spotted puffer fish [PDF]

, 2010
Background Calcium ion is tightly regulated in body fluids and for euryhaline fish, which are exposed to rapid changes in environmental [Ca2+], homeostasis is especially challenging. The gill is the main organ of active calcium uptake and therefore plays
Canario, Adelino V. M., Matsumura, H., Pinto, Patricia IS, Power, Deborah, Reinhardt, Richard, Terauchi, Ryohei, Thorne, Michael A. S.   +6 more
core   +5 more sources

Titin Is Present in the Elastic Tethers That Connect Separating Anaphase Chromosomes in Crane‐Fly Spermatocytes

Cytoskeleton, EarlyView.
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos, Maral Janan, Martina Krüger, Aavo‐Valdur Mikelsaar, Arthur Forer, Rose Sheykhani   +5 more
wiley   +1 more source

Surface plasmon resonance study of the actin-myosin sarcomeric complex and tubulin dimers

, 2003
Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration.
Alexander A. Kolomenskii, Andreas Mershin, Brekhovskikh L. M., Brown J. A., Dimitri V. Nanopoulos, Earp R. L., Hans A. Schuessler, Mershin A., Raether H.   +8 more
core   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Three distinct sarcomeric patterns of skeletal muscle revealed by SHG and TPEF microscopy. [PDF]

, 2009
International audienceWe have extensively characterized the sarcomeric SHG signal as a function of animal species (rat versus xenopus), age (adult versus larval) and tissue preparation (fixed or fresh) and we found that the main feature of this signal is
Bellanger, Jean-Jacques, Recher, Gaëlle, Richard, Patrick, Rouède, Denis, Simon, Antoine, Tiaho, François   +5 more
core   +3 more sources

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Immunological Characterization of the Subunit of the 100 angstrom Filaments from Muscle Cells [PDF]

, 1976
We report the immunological characterization of the subunit of the intermediate sized (100 angstrom) filaments from muscle cells. The protein as isolated from smooth muscle (chicken gizzard) has an apparent molecular weight of 50,000.
Hubbard, Bruce D., Lazarides, Elias
core